JN Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
 QUICK SEARCH:   [advanced]


     


J Neurophysiol (December 26, 2007). doi:10.1152/jn.00772.2007
This Article
Right arrow Full Text (PDF)
Right arrow Corrected Acknowledgments
Right arrow All Versions of this Article:
99/3/1333    most recent
00772.2007v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Muresan, R. C.
Right arrow Articles by Nikolic, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Muresan, R. C.
Right arrow Articles by Nikolic, D.
Submitted on July 9, 2007
Accepted on December 22, 2007

The Oscillation Score: An Efficient Method for Estimating Oscillation Strength in Neuronal Activity

Raul Cristian Muresan1*, Ovidiu Florin Jurjut1, Vasile Vlad Moca1, Wolf Singer2, and Danko Nikolic2

1 Neuroscience, Frankfurt Institute for Advanced Studies, Frankfurt am Main, Hessen, Germany; Neuroscience, Center for Cognitive and Neural Studies, Cluj-Napoca, Cluj, Romania; Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Hessen, Germany
2 Neuroscience, Frankfurt Institute for Advanced Studies, Frankfurt am Main, Hessen, Germany; Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Hessen, Germany

* To whom correspondence should be addressed. E-mail: contact{at}raulmuresan.ro.

We present a method that estimates the strength of neuronal oscillations at the cellular level, relying on auto-correlation histograms computed on spike trains. The method delivers a number, termed oscillation score, that estimates the degree to which a neuron is oscillating in a given frequency band. Moreover, it can also reliably identify the oscillation frequency and strength in the given band, independently of the oscillation in other frequency bands, and thus it can handle superimposed oscillations on multiple scales (theta, alpha, beta, gamma etc). The method is relatively simple and fast. It can cope with a low number of spikes, converging exponentially-fast with the number of spikes, to a stable estimation of the oscillation strength. Hence, it lends itself to the analysis of spike-sorted single unit activity from electrophysiological recordings. We show that the method performs well on experimental data recorded from cat visual cortex and also compares favorably to other methods. In addition, we provide a measure, named confidence score, that determines the stability of the oscillation score estimate over trials.







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 2007 by the The American Physiological Society.