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This Article Full Text Full Text (PDF) Supplemental Video All Versions of this Article: 102/1/12    most recent 00351.2009v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Beraneck, M. Articles by Lambert, F. M. PubMed PubMed Citation Articles by Beraneck, M. Articles by Lambert, F. M.

Neuro Forum

Impaired Perception of Gravity Leads to Altered Head Direction Signals: What Can We Learn From Vestibular-Deficient Mice?

Laboratoire de Neurobiologie des Réseaux Sensorimoteurs, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7060, Université Paris Descartes, Unité de Formation et de Recherche Biomédicale des Saints-Pères, Paris, France

ABSTRACT

Many mutant mouse strains display pathological behaviors, such as head tilts, head bobbing, or circling and waltzing, strongly suggesting that their vestibular system is impaired. Recently, Yoder and Taube studied head direction signals in tilted mutant mice, which have an impaired gravitation sensitivity in the vestibular periphery. Here we summarize their findings and discuss a caveat related to the general use of mutant mouse strains in systems physiology.