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J Neurophysiol 102: 9-11, 2009. First published May 6, 2009; doi:10.1152/jn.00290.2009
0022-3077/09 $8.00
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Neuro Forum

Identifying the Functional Role of Martinotti Cells in Cortical Sensory Processing

James C. H. Cottam

Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

ABSTRACT

Inhibitory interneurons are highly diverse, although the functional significance of their diversity is not yet well understood. This presents a barrier to understanding neural computation at the local circuit level. This review focuses on a recent study by Murayama et al. who used a novel in vivo technique in neocortex to demonstrate a specific sensory processing function of dendritic-targeting Martinotti interneurons. The function of Martinotti cells arises from their interaction with layer 5 pyramidal cell dendrites.

Address for reprint requests and other correspondence: J. Cottam, Wolfson Institute for Biomedical Research, The Cruciform Building, Gower Street, University College London, London, WC1E 6BT, UK (E-mail: j.cottam{at}ucl.ac.uk)






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