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J Neurophysiol 102: 645-647, 2009. First published June 10, 2009; doi:10.1152/jn.00406.2009
0022-3077/09 $8.00
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NEURO FORUM

Risky Business: Disambiguating Ambiguity-Related Responses in the Brain

Martin O'Neill and Shunsuke Kobayashi

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

ABSTRACT

Previous functional MRI studies reported neural correlates of risk and ambiguity based on behavioral economic theories. A recent study controlled for uncertainty by adding noise to information of an impending aversive event and demonstrated brain areas that did not track the degree of uncertainty: the activation peaked when the degraded information could be restored by cognitive efforts. In this review, we discuss how the variables defined in economics and cognitive psychology frameworks can be dissociated.

Address for reprint requests and other correspondence: M. O'Neill or S. Kobayashi, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge, CB2 3DY, UK (E-mail: mo293{at}cam.ac.uk) or (E-mail: skoba-tky{at}umin.ac.jp).






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