JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 54: 40-60, 1985;
0022-3077/85 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gellman, R.
Right arrow Articles by Houk, J. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gellman, R.
Right arrow Articles by Houk, J. C.

Journal of Neurophysiology, Vol 54, Issue 1 40-60, Copyright © 1985 by APS

ARTICLES

Inferior olivary neurons in the awake cat: detection of contact and passive body displacement

R. Gellman, A. R. Gibson and J. C. Houk

We have recorded from 306 neurons in the inferior olive of six alert cats. Most of the cats were trained to perform a simple task with the forelimb. We observed the neural responses to a wide variety of cutaneous and proprioceptive stimuli, as well as responses during spontaneous and learned active movements. Neurons responsive to somatosensory stimulation were found in all parts of the inferior olive, and they were roughly evenly divided between those responsive to cutaneous stimulation and those responsive to proprioceptive stimulation. In the dorsal accessory olive all neurons were responsive to somatosensory stimulation. In the medial accessory nucleus 88% and in the principal olive 74% of cells were responsive to somatosensory stimulation. Cells responsive to cutaneous stimulation usually had small receptive fields, commonly on the paw. These cells had low-threshold responses to one or more forms of cutaneous stimulation and typically fired one spike at the onset of the stimulus on 80% or more of stimulus applications. Cells responsive to proprioceptive stimulation most commonly responded to passive displacements of a limb. These cells were often very sensitive, responding to linear displacements of less than 1 cm in one specific direction. No cells in our sample responded reliably during active movement by the animal. Only 21% of cells responding to passive proprioceptive stimulation showed any modulation during active movement, and the modulation was weak. Likewise, cells responsive to cutaneous stimulation generally failed to respond when a similar stimulus was produced by an active movement by the animal. Exceptions to this were stimuli produced during exploratory movements or when the receptive field unexpectedly made contact with an object during active movement. Electrical stimulation applied in the inferior olive failed to evoke movements or to modify ongoing movement. Our results are consistent with the hypothesis that inferior olivary neurons function as somatic event detectors responding particularly reliably to unexpected stimuli.


This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
N. C. Rowland and D. Jaeger
Responses to Tactile Stimulation in Deep Cerebellar Nucleus Neurons Result From Recurrent Activation in Multiple Pathways
J Neurophysiol, February 1, 2008; 99(2): 704 - 717.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. Khosrovani, R. S. Van Der Giessen, C. I. De Zeeuw, and M. T. G. De Jeu
In vivo mouse inferior olive neurons exhibit heterogeneous subthreshold oscillations and spiking patterns
PNAS, October 2, 2007; 104(40): 15911 - 15916.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
P. M. Bays and D. M. Wolpert
Computational principles of sensorimotor control that minimize uncertainty and variability
J. Physiol., January 15, 2007; 578(2): 387 - 396.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. Xu, T. Liu, J. Ashe, and K. O. Bushara
Role of the olivo-cerebellar system in timing.
J. Neurosci., May 31, 2006; 26(22): 5990 - 5995.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Y. Dhaher, A. D. Tsoumanis, T. T. Houle, and W. Z. Rymer
Neuromuscular Reflexes Contribute to Knee Stiffness During Valgus Loading
J Neurophysiol, May 1, 2005; 93(5): 2698 - 2709.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. Pardoe, S. A. Edgley, T. Drew, and R. Apps
Changes in Excitability of Ascending and Descending Inputs to Cerebellar Climbing Fibers during Locomotion
J. Neurosci., March 17, 2004; 24(11): 2656 - 2666.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. A. Nicholson and J. H. Freeman Jr.
Developmental Changes in Evoked Purkinje Cell Complex Spike Responses
J Neurophysiol, October 1, 2003; 90(4): 2349 - 2357.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
T. J. EBNER, M. T. V. JOHNSON, A. ROITMAN, and Q. FU
What Do Complex Spikes Signal about Limb Movements?
Ann. N.Y. Acad. Sci., December 1, 2002; 978(1): 205 - 218.
[Abstract] [Full Text] [PDF]

Home page
 Ann. N. Y. Acad. Sci.Home page
A. R. GIBSON, K. M. HORN, and M. PONG
Inhibitory Control of Olivary Discharge
Ann. N.Y. Acad. Sci., December 1, 2002; 978(1): 219 - 231.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
I. E. Brown and J. M. Bower
The Influence of Somatosensory Cortex on Climbing Fiber Responses in the Lateral Hemispheres of the Rat Cerebellum after Peripheral Tactile Stimulation
J. Neurosci., August 1, 2002; 22(15): 6819 - 6829.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
M. Ito
Cerebellar Long-Term Depression: Characterization, Signal Transduction, and Functional Roles
Physiol Rev, July 1, 2001; 81(3): 1143 - 1195.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. J. Hartmann and J. M. Bower
Tactile Responses in the Granule Cell Layer of Cerebellar Folium Crus IIa of Freely Behaving Rats
J. Neurosci., May 15, 2001; 21(10): 3549 - 3563.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. A. Nicholson and J. H. Freeman Jr
Developmental Changes in Eye-Blink Conditioning and Neuronal Activity in the Inferior Olive
J. Neurosci., November 1, 2000; 20(21): 8218 - 8226.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
O. Hidaka, T. Morimoto, T. Kato, Y. Masuda, T. Inoue, and K. Takada
Behavior of Jaw Muscle Spindle Afferents During Cortically Induced Rhythmic Jaw Movements in the Anesthetized Rabbit
J Neurophysiol, November 1, 1999; 82(5): 2633 - 2640.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. M. Horn, T. M. Hamm, and A. R. Gibson
Red Nucleus Stimulation Inhibits Within the Inferior Olive
J Neurophysiol, December 1, 1998; 80(6): 3127 - 3136.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. A. Doeringer and N. Hogan
Intermittency in Preplanned Elbow Movements Persists in the Absence of Visual Feedback
J Neurophysiol, October 1, 1998; 80(4): 1787 - 1799.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Kobayashi, K. Kawano, A. Takemura, Y. Inoue, T. Kitama, H. Gomi, and M. Kawato
Temporal Firing Patterns of Purkinje Cells in the Cerebellar Ventral Paraflocculus During Ocular Following Responses in Monkeys II. Complex Spikes
J Neurophysiol, August 1, 1998; 80(2): 832 - 848.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. R. Mason, L. E. Miller, J. F. Baker, and J. C. Houk
Organization of Reaching and Grasping Movements in the Primate Cerebellar Nuclei as Revealed by Focal Muscimol Inactivations
J Neurophysiol, February 1, 1998; 79(2): 537 - 554.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J. Bloedel
The cerebellum and memory storage
Science, December 18, 1987; 238(4834): 1728 - 1730.
[PDF]

Home page
 ScienceHome page
R. F. THOMPSON
Response: The Cerebellum and Memory Storage
Science, December 18, 1987; 238(4834): 1729 - 1730.
[PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online