JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 54: 513-519, 1985;
0022-3077/85 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shea, V. K.
Right arrow Articles by Perl, E. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shea, V. K.
Right arrow Articles by Perl, E. R.

Journal of Neurophysiology, Vol 54, Issue 3 513-519, Copyright © 1985 by APS

ARTICLES

Failure of sympathetic stimulation to affect responsiveness of rabbit polymodal nociceptors

V. K. Shea and E. R. Perl

The responses of polymodal nociceptors with unmyelinated (C) fibers of the rabbit's great auricular nerve were examined with and without intermittent stimulation of the ipsilateral cervical sympathetic trunk. The receptive field of each polymodal nociceptor was heated twice in a stepwise manner from 30 to 50 or 55 degrees C in 5 degree C steps. For each unit, one heating trial was a control trial and the other was accompanied by sympathetic stimulation. The order of the control and sympathetic stimulation trials and the maximum testing temperature were varied systematically among the units examined. The initial responses of polymodal nociceptors in the first heating trial in the presence of sympathetic stimulation were similar to the responses of units whose first heating was a control trial. Units whose receptive fields were tested to a maximum temperature of 50 degrees C in the first trial displayed enhanced responses to heat in their second trial (sensitization), while units tested initially to 55 degrees C responded less briskly during their second heating trial (depression). However, the occurrence of sympathetic stimulation in the second heating trials had no apparent effect on the responses to heat of sensitized or depressed elements. Alterations in the numbers of impulses, instantaneous frequency, or pattern of impulse activity of individual units could not be attributed to sympathetic stimulation.(ABSTRACT TRUNCATED AT 250 WORDS)


This article has been cited by other articles:


Home page
 BrainHome page
M. Elam, B. Olausson, J. O. Skarphedinsson1, and B. G. Wallin
Does sympathetic nerve discharge affect the firing of polymodal C-fibre afferents in humans?
Brain, December 1, 1999; 122(12): 2237 - 2244.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Z. Ali, M. Ringkamp, T. V. Hartke, H. F. Chien, N. A. Flavahan, J. N. Campbell, and R. A. Meyer
Uninjured C-Fiber Nociceptors Develop Spontaneous Activity and alpha -Adrenergic Sensitivity Following L6 Spinal Nerve Ligation in Monkey
J Neurophysiol, February 1, 1999; 81(2): 455 - 466.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J Sato and E. Perl
Adrenergic excitation of cutaneous pain receptors induced by peripheral nerve injury
Science, March 29, 1991; 251(5001): 1608 - 1610.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online