JN AJP: Endocrinology and Metabolism
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 54: 615-635, 1985;
0022-3077/85 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Simons, D. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Simons, D. J.

Journal of Neurophysiology, Vol 54, Issue 3 615-635, Copyright © 1985 by APS

ARTICLES

Temporal and spatial integration in the rat SI vibrissa cortex

D. J. Simons

Glass micropipettes were used to record the activity of 124 single units in the somatosensory vibrissa cortex (SI) of 16 rats in response to combined deflections of contralateral vibrissae. Compact multiangular electromechanical stimulators were used to stimulate individual vibrissal hairs alone or in combinations of two or three adjacent whiskers. Each whisker was stimulated independently to produce controlled temporal and spatial patterns of mechanical stimuli. Following displacement of a vibrissa, unit discharges to subsequent deflections of adjacent whiskers are reduced in a time-dependent fashion. Response suppression is strongest at short interdeflection intervals, i.e., 10-20 ms and decreases progressively during the 50-100 ms following the first deflection. In many cases this period also corresponds with a reduction in ongoing unit discharges. Response suppression was not observed for first-order neurons recorded in the trigeminal ganglion of barbiturate-anesthetized rats. In the cortex, the presence and/or degree of response suppression depends on a number of spatial factors. These include 1) the angular direction(s) in which the individual hairs are moved, 2) the sequence in which two whiskers are deflected, that is, which one is deflected first, 3) the particular combination of whiskers stimulated, and 4) the number (2 or 3) of vibrissae comprising the multiwhisker stimulus. Within a vertical electrode penetration, one particular whisker typically elicits the strongest excitatory and inhibitory effects; other, nearby vibrissae elicit variable (or no) excitation or inhibition. Excitatory and inhibitory subregions of a receptive field could thus be distributed asymmetrically around the maximally effective whisker. In these cases, the receptive fields displayed spatial orientations. Quantitative criteria were used to classify 30 cortical units on the basis of the distribution of inhibitory subregions on either side of the maximally effective whisker. Twenty-one of these cells had receptive fields (RFs) with symmetrical inhibitory side regions. Responses of the other nine units were strongly suppressed by a preceding deflection of a vibrissa on one side but relatively unaffected, or even slightly facilitated, by preceding deflection of the whisker on the other side.(ABSTRACT TRUNCATED AT 400 WORDS)


This article has been cited by other articles:


Home page
 Cereb CortexHome page
K. D. Alloway
Information Processing Streams in Rodent Barrel Cortex: The Differential Functions of Barrel and Septal Circuits
Cereb Cortex, May 1, 2008; 18(5): 979 - 989.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. Lak, E. Arabzadeh, and M. E. Diamond
Enhanced Response of Neurons in Rat Somatosensory Cortex to Stimuli Containing Temporal Noise
Cereb Cortex, May 1, 2008; 18(5): 1085 - 1093.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. Scholl, X. Gao, and M. Wehr
Level Dependence of Contextual Modulation in Auditory Cortex
J Neurophysiol, April 1, 2008; 99(4): 1616 - 1627.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. J. Drew and D. E. Feldman
Representation of Moving Wavefronts of Whisker Deflection in Rat Somatosensory Cortex
J Neurophysiol, September 1, 2007; 98(3): 1566 - 1580.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
T. Celikel and B. Sakmann
Sensory integration across space and in time for decision making in the somatosensory system of rodents
PNAS, January 23, 2007; 104(4): 1395 - 1400.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Katz, J. E. Heiss, and I. Lampl
Cross-Whisker Adaptation of Neurons in the Rat Barrel Cortex
J. Neurosci., December 20, 2006; 26(51): 13363 - 13372.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. Shlosberg, Y. Amitai, and R. Azouz
Time-Dependent, Layer-Specific Modulation of Sensory Responses Mediated by Neocortical Layer 1
J Neurophysiol, December 1, 2006; 96(6): 3170 - 3182.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
P. Melzer, R. N. S. Sachdev, N. Jenkinson, and F. F. Ebner
Stimulus Frequency Processing in Awake Rat Barrel Cortex.
J. Neurosci., November 22, 2006; 26(47): 12198 - 12205.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. M. Rodgers, A. M. Benison, and D. S. Barth
Two-Dimensional Coincidence Detection in the Vibrissa/Barrel Field
J Neurophysiol, October 1, 2006; 96(4): 1981 - 1990.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. F. Civillico and D. Contreras
Integration of Evoked Responses in Supragranular Cortex Studied With Optical Recordings In Vivo
J Neurophysiol, July 1, 2006; 96(1): 336 - 351.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
B. Tutunculer, G. Foffani, B. T. Himes, and K. A. Moxon
Structure of the Excitatory Receptive Fields of Infragranular Forelimb Neurons in the Rat Primary Somatosensory Cortex Responding To Touch
Cereb Cortex, June 1, 2006; 16(6): 791 - 810.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. M. Webber and G. B. Stanley
Transient and Steady-State Dynamics of Cortical Adaptation
J Neurophysiol, May 1, 2006; 95(5): 2923 - 2932.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A.-R. Boloori and G. B. Stanley
The dynamics of spatiotemporal response integration in the somatosensory cortex of the vibrissa system.
J. Neurosci., April 5, 2006; 26(14): 3767 - 3782.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. M. Benison, T. D. Ard, A. M. Crosby, and D. S. Barth
Temporal Patterns of Field Potentials in Vibrissa/Barrel Cortex Reveal Stimulus Orientation and Shape
J Neurophysiol, April 1, 2006; 95(4): 2242 - 2251.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. J. Higley and D. Contreras
Balanced Excitation and Inhibition Determine Spike Timing during Frequency Adaptation
J. Neurosci., January 11, 2006; 26(2): 448 - 457.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. R. Aguilar and M. A. Castro-Alamancos
Spatiotemporal Gating of Sensory Inputs in Thalamus during Quiescent and Activated States
J. Neurosci., November 23, 2005; 25(47): 10990 - 11002.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
H. Kida, S. Shimegi, and H. Sato
Similarity of Direction Tuning Among Responses to Stimulation of Different Whiskers in Neurons of Rat Barrel Cortex
J Neurophysiol, September 1, 2005; 94(3): 2004 - 2018.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
M. A. L Nicolelis
Computing with thalamocortical ensembles during different behavioural states
J. Physiol., July 1, 2005; 566(1): 37 - 47.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. E. Kwegyir-Afful, R. M. Bruno, D. J. Simons, and A. Keller
The Role of Thalamic Inputs in Surround Receptive Fields of Barrel Neurons
J. Neurosci., June 22, 2005; 25(25): 5926 - 5934.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. J. Staba, T. D. Ard, A. M. Benison, and D. S. Barth
Intracortical Pathways Mediate Nonlinear Fast Oscillation (>200 Hz) Interactions Within Rat Barrel Cortex
J Neurophysiol, May 1, 2005; 93(5): 2934 - 2939.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. C. Wiest, N. Bentley, and M. A. L. Nicolelis
Heterogeneous Integration of Bilateral Whisker Signals by Neurons in Primary Somatosensory Cortex of Awake Rats
J Neurophysiol, May 1, 2005; 93(5): 2966 - 2973.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. J. Higley and D. Contreras
Integration of Synaptic Responses to Neighboring Whiskers in Rat Barrel Cortex In Vivo
J Neurophysiol, April 1, 2005; 93(4): 1920 - 1934.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
V. Ego-Stengel, T. Mello E Souza, V. Jacob, and D. E. Shulz
Spatiotemporal Characteristics of Neuronal Sensory Integration in the Barrel Cortex of the Rat
J Neurophysiol, March 1, 2005; 93(3): 1450 - 1467.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
V. Khatri, J. A. Hartings, and D. J. Simons
Adaptation in Thalamic Barreloid and Cortical Barrel Neurons to Periodic Whisker Deflections Varying in Frequency and Velocity
J Neurophysiol, December 1, 2004; 92(6): 3244 - 3254.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. N. S. Sachdev, F. F. Ebner, and C. J. Wilson
Effect of Subthreshold Up and Down States on the Whisker-Evoked Response in Somatosensory Cortex
J Neurophysiol, December 1, 2004; 92(6): 3511 - 3521.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. T. Porter and D. Nieves
Presynaptic GABAB Receptors Modulate Thalamic Excitation of Inhibitory and Excitatory Neurons in the Mouse Barrel Cortex
J Neurophysiol, November 1, 2004; 92(5): 2762 - 2770.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Zhang and K. D. Alloway
Stimulus-Induced Intercolumnar Synchronization of Neuronal Activity in Rat Barrel Cortex: A Laminar Analysis
J Neurophysiol, September 1, 2004; 92(3): 1464 - 1478.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. M. Webber and G. B. Stanley
Nonlinear Encoding of Tactile Patterns in the Barrel Cortex
J Neurophysiol, May 1, 2004; 91(5): 2010 - 2022.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. J. Higley and D. Contreras
Nonlinear Integration of Sensory Responses in the Rat Barrel Cortex: An Intracellular Study In Vivo
J. Neurosci., November 12, 2003; 23(32): 10190 - 10200.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. Fox, N. Wright, H. Wallace, and S. Glazewski
The Origin of Cortical Surround Receptive Fields Studied in the Barrel Cortex
J. Neurosci., September 10, 2003; 23(23): 8380 - 8391.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. E. Garabedian, S. R. Jones, M. M. Merzenich, A. Dale, and C. I. Moore
Band-Pass Response Properties of Rat SI Neurons
J Neurophysiol, September 1, 2003; 90(3): 1379 - 1391.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. J. Hartmann, N. J. Johnson, R. B. Towal, and C. Assad
Mechanical Characteristics of Rat Vibrissae: Resonant Frequencies and Damping in Isolated Whiskers and in the Awake Behaving Animal
J. Neurosci., July 23, 2003; 23(16): 6510 - 6519.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. S. Barth
Submillisecond Synchronization of Fast Electrical Oscillations in Neocortex
J. Neurosci., March 15, 2003; 23(6): 2502 - 2510.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. S. Minnery and D. J. Simons
Response Properties of Whisker-Associated Trigeminothalamic Neurons in Rat Nucleus Principalis
J Neurophysiol, January 1, 2003; 89(1): 40 - 56.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
D. J. Pinto, J. A. Hartings, J. C. Brumberg, and D. J. Simons
Cortical Damping: Analysis of Thalamocortical Response Transformations in Rodent Barrel Cortex
Cereb Cortex, January 1, 2003; 13(1): 33 - 44.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. A. Castro-Alamancos
Role of Thalamocortical Sensory Suppression during Arousal: Focusing Sensory Inputs in Neocortex
J. Neurosci., November 15, 2002; 22(22): 9651 - 9655.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. N. S. Sachdev and K. C. Catania
Receptive Fields and Response Properties of Neurons in the Star-Nosed Mole's Somatosensory Fovea
J Neurophysiol, May 1, 2002; 87(5): 2602 - 2611.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. M. O'Connor, R. W. Berg, and D. Kleinfeld
Coherent Electrical Activity Between Vibrissa Sensory Areas of Cerebellum and Neocortex Is Enhanced During Free Whisking
J Neurophysiol, April 1, 2002; 87(4): 2137 - 2148.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Castro-Alamancos
Properties of Primary Sensory (Lemniscal) Synapses in the Ventrobasal Thalamus and the Relay of High-Frequency Sensory Inputs
J Neurophysiol, February 1, 2002; 87(2): 946 - 953.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C. C. H. Petersen and B. Sakmann
Functionally Independent Columns of Rat Somatosensory Barrel Cortex Revealed with Voltage-Sensitive Dye Imaging
J. Neurosci., November 1, 2001; 21(21): 8435 - 8446.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. J. Krupa, M. S. Matell, A. J. Brisben, L. M. Oliveira, and M. A. L. Nicolelis
Behavioral Properties of the Trigeminal Somatosensory System in Rats Performing Whisker-Dependent Tactile Discriminations
J. Neurosci., August 1, 2001; 21(15): 5752 - 5763.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. G. Shuler, D. J. Krupa, and M. A. L. Nicolelis
Bilateral Integration of Whisker Information in the Primary Somatosensory Cortex of Rats
J. Neurosci., July 15, 2001; 21(14): 5251 - 5261.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. Ahissar, R. Sosnik, K. Bagdasarian, and S. Haidarliu
Temporal Frequency of Whisker Movement. II. Laminar Organization of Cortical Representations
J Neurophysiol, July 1, 2001; 86(1): 354 - 367.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
V. Ego-Stengel, D. E. Shulz, S. Haidarliu, R. Sosnik, and E. Ahissar
Acetylcholine-Dependent Induction and Expression of Functional Plasticity in the Barrel Cortex of the Adult Rat
J Neurophysiol, July 1, 2001; 86(1): 422 - 437.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. Schubert, J. F. Staiger, N. Cho, R. Kotter, K. Zilles, and H. J. Luhmann
Layer-Specific Intracolumnar and Transcolumnar Functional Connectivity of Layer V Pyramidal Cells in Rat Barrel Cortex
J. Neurosci., May 15, 2001; 21(10): 3580 - 3592.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. A. Ghazanfar and M. A. L. Nicolelis
Feature Article: The Structure and Function of Dynamic Cortical and Thalamic Receptive Fields
Cereb Cortex, March 1, 2001; 11(3): 183 - 193.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. N. S. Sachdev, H. Sellien, and F. F. Ebner
Direct Inhibition Evoked by Whisker Stimulation in Somatic Sensory (SI) Barrel Field Cortex of the Awake Rat
J Neurophysiol, September 1, 2000; 84(3): 1497 - 1504.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Shimegi, T. Akasaki, T. Ichikawa, and H. Sato
Physiological and Anatomical Organization of Multiwhisker Response Interactions in the Barrel Cortex of Rats
J. Neurosci., August 15, 2000; 20(16): 6241 - 6248.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. L. Barth, M. McKenna, S. Glazewski, P. Hill, S. Impey, D. Storm, and K. Fox
Upregulation of cAMP Response Element-Mediated Gene Expression during Experience-Dependent Plasticity in Adult Neocortex
J. Neurosci., June 1, 2000; 20(11): 4206 - 4216.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
V. Rema and F. F. Ebner
Effect of Enriched Environment Rearing on Impairments in Cortical Excitability and Plasticity after Prenatal Alcohol Exposure
J. Neurosci., December 15, 1999; 19(24): 10993 - 11006.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Shimegi, T. Ichikawa, T. Akasaki, and H. Sato
Temporal Characteristics of Response Integration Evoked by Multiple Whisker Stimulations in the Barrel Cortex of Rats
J. Neurosci., November 15, 1999; 19(22): 10164 - 10175.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. C. Brumberg, D. J Pinto, and D. J. Simons
Cortical Columnar Processing in the Rat Whisker-to-Barrel System
J Neurophysiol, October 1, 1999; 82(4): 1808 - 1817.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. Goldreich, H. T. Kyriazi, and D. J. Simons
Functional Independence of Layer IV Barrels in Rodent Somatosensory Cortex
J Neurophysiol, September 1, 1999; 82(3): 1311 - 1316.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. S. Jones and D. S. Barth
Spatiotemporal Organization of Fast (>200 Hz) Electrical Oscillations in Rat Vibrissa/Barrel Cortex
J Neurophysiol, September 1, 1999; 82(3): 1599 - 1609.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. E. Fanselow and M. A. L. Nicolelis
Behavioral Modulation of Tactile Responses in the Rat Somatosensory System
J. Neurosci., September 1, 1999; 19(17): 7603 - 7616.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. A. Ghazanfar and M. A.L. Nicolelis
Spatiotemporal Properties of Layer V Neurons of the Rat Primary Somatosensory Cortex
Cereb Cortex, June 1, 1999; 9(4): 348 - 361.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. J. Zhu and B. W. Connors
Intrinsic Firing Patterns and Whisker-Evoked Synaptic Responses of Neurons in the Rat Barrel Cortex
J Neurophysiol, March 1, 1999; 81(3): 1171 - 1183.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. L. Kwan, J. A. Demaro, J. W. Hu, M. F. Jacquin, and B. J. Sessle
C-Fiber Depletion Alters Response Properties of Neurons in Trigeminal Nucleus Principalis
J Neurophysiol, February 1, 1999; 81(2): 435 - 446.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. I. Moore and S. B. Nelson
Spatio-Temporal Subthreshold Receptive Fields in the Vibrissa Representation of Rat Primary Somatosensory Cortex
J Neurophysiol, December 1, 1998; 80(6): 2882 - 2892.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. F. Cannestra, N. Pouratian, M. H. Shomer, and A. W. Toga
Refractory Periods Observed by Intrinsic Signal and Fluorescent Dye Imaging
J Neurophysiol, September 1, 1998; 80(3): 1522 - 1532.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Maalouf, A. A. Miasnikov, and R. W. Dykes
Blockade of Cholinergic Receptors in Rat Barrel Cortex Prevents Long-Term Changes in the Evoked Potential During Sensory Preconditioning
J Neurophysiol, August 1, 1998; 80(2): 529 - 545.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. R. Sheth, C. I. Moore, and M. Sur
Temporal Modulation of Spatial Borders in Rat Barrel Cortex
J Neurophysiol, January 1, 1998; 79(1): 464 - 470.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
N. Rocamora, E. Welker, M. Pascual, and E. Soriano
Upregulation of BDN