| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Neurophysiology, Vol 63, Issue 5 1213-1225, Copyright © 1990 by APS
ARTICLES |
G. H. Recanzone, T. T. Allard, W. M. Jenkins and M. M. Merzenich
Department of Physiology, University of California, San Francisco 94143-0732.
1. Receptive fields (RFs) of neurons in the primary somatosensory (SI) cortex were defined before, during, and after electrical stimulation of myelinated fibers in the dorsal cutaneous branch of the ulnar nerve in adult pentobarbital sodium-anesthetized cats. 2. This stimulation resulted in an approximately threefold increase of SI multiunit RF sizes. Substantial changes were first recorded within 1-2 h of stimulation. RFs typically enlarged continuously over a several-hour stimulation period, then stabilized. 3. RF-area increases were observed within both the forepaw and hindpaw representational zones in the SI cortex contralateral to the stimulated forepaw nerve. RF sizes did not increase in the ipsilateral SI body surface representation or in sham-stimulation control animals. 4. Preliminary studies indicate that stimulation-induced changes can be halted and often reversed by the intravenous administration of the opiate antagonist naloxone. 5. These observations suggest a global naloxone-sensitive modulatory system that operates on large-diameter afferent inputs in the cat somatosensory system. The increases in RF size occur under nerve-stimulation conditions similar to those that result in the generation of widespread analgesia (Chung et al. 1984a,b; Gamble and Milne 1986; Toda and Ichioka 1978).
This article has been cited by other articles:
|
|
 |
|
  M. L. Stavrinou, S. Della Penna, V. Pizzella, K. Torquati, F. Cianflone, R. Franciotti, A. Bezerianos, G. L. Romani, and P. M. Rossini Temporal Dynamics of Plastic Changes in Human Primary Somatosensory Cortex after Finger Webbing Cereb Cortex, September 1, 2007; 17(9): 2134 - 2142. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. J. Uhlrich, K. A. Manning, M. L. O'Laughlin, and W. W. Lytton Photic-Induced Sensitization: Acquisition of an Augmenting Spike-Wave Response in the Adult Rat Through Repeated Strobe Exposure J Neurophysiol, December 1, 2005; 94(6): 3925 - 3937. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Bao, E. F. Chang, J. D. Davis, K. T. Gobeske, and M. M. Merzenich Progressive Degradation and Subsequent Refinement of Acoustic Representations in the Adult Auditory Cortex J. Neurosci., November 26, 2003; 23(34): 10765 - 10775. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. SCHLAUG The Brain of Musicians: A Model for Functional and Structural Adaptation Ann. N.Y. Acad. Sci., June 1, 2001; 930(1): 281 - 299. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. L. Small and A. Solodkin Review : The Neurobiology of Stroke Rehabilitation Neuroscientist, November 1, 1998; 4(6): 426 - 434. [Abstract] [PDF]
|
|
|
|
|
|
A. Sterr, M. M. Muller, T. Elbert, B. Rockstroh, C. Pantev, and E. Taub Perceptual Correlates of Changes in Cortical Representation of Fingers in Blind Multifinger Braille Readers J. Neurosci., June 1, 1998; 18(11): 4417 - 4423. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Harsanyi and M. J. Friedlander Transient Synaptic Potentiation in the Visual Cortex. I. Cellular Mechanisms J Neurophysiol, March 1, 1997; 77(3): 1269 - 1283. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
