JN Journal of Neurophysiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 64: 1055-1066, 1990;
0022-3077/90 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rolls, E. T.
Right arrow Articles by Sienkiewicz, Z. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rolls, E. T.
Right arrow Articles by Sienkiewicz, Z. J.

Journal of Neurophysiology, Vol 64, Issue 4 1055-1066, Copyright © 1990 by APS

ARTICLES

Gustatory responses of single neurons in the caudolateral orbitofrontal cortex of the macaque monkey

E. T. Rolls, S. Yaxley and Z. J. Sienkiewicz
Department of Experimental Psychology, University of Oxford, United Kingdom.

1. In recordings made from 3,120 single neurons, a secondary cortical taste area was found in the caudolateral part of the orbitofrontal cortex of the cynomolgus macaque monkey, Macaca fascicularis. The area is part of the dysgranular field of the orbitofrontal cortex and is situated anterior to the primary cortical taste areas in the frontal opercular and adjoining insular cortices. 2. The responses of 49 single neurons with gustatory responses in the caudolateral orbitofrontal taste cortex were analyzed using the taste stimuli glucose, NaCl, HCl, quinine HCl, water, and blackcurrant juice. 3. A breadth-of-tuning coefficient was calculated for each neuron. This is a metric that can range from 0.0 for a neuron that responds specifically to only one of the four basic taste stimuli to 1.0 for one that responds equally to all four stimuli. The mean coefficient for 49 cells in the caudolateral orbitofrontal cortex was 0.39. This tuning is much sharper than that of neurons in the nucleus of the solitary tract of the monkey, and sharper than that of neurons in the primary frontal opercular and insular taste cortices. 4. A cluster analysis showed that at least seven different groups of neurons were present. For each of the taste stimuli glucose, blackcurrant juice, NaCl, and water, there was one group of neurons that responded much more to that tastant than to the other tastants. The other groups of neurons responded to two or more of these tastants, such as glucose and blackcurrant juice. In this particular region neurons were not found with large responses to HCl or quinine HCl, although such neurons could be present in other parts of the orbitofrontal cortex. 5. On the basis of this and other evidence it is concluded that in the caudolateral orbitofrontal cortex there is a secondary cortical taste area in which the tuning of neurons has become finer than in early areas of taste processing, in which foods, water, and NaCl are strongly represented and where motivation dependence first becomes manifest in the taste system.


This article has been cited by other articles:


Home page
 Cereb CortexHome page
F. Grabenhorst, E. T. Rolls, and A. Bilderbeck
How Cognition Modulates Affective Responses to Taste and Flavor: Top-down Influences on the Orbitofrontal and Pregenual Cingulate Cortices
Cereb Cortex, July 1, 2008; 18(7): 1549 - 1559.
[Abstract] [Full Text] [PDF]

Home page
 Soc Cogn Affect NeurosciHome page
M. Koenigs and D. Tranel
Prefrontal cortex damage abolishes brand-cued changes in cola preference
Soc Cogn Affect Neurosci, March 1, 2008; 3(1): 1 - 6.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. M. Simmons and B. J. Richmond
Dynamic Changes in Representations of Preceding and Upcoming Reward in Monkey Orbitofrontal Cortex
Cereb Cortex, January 1, 2008; 18(1): 93 - 103.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. D. Woolley, M. -L. Gorno-Tempini, W. W. Seeley, K. Rankin, S. S. Lee, B. R. Matthews, and B. L. Miller
Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia
Neurology, October 2, 2007; 69(14): 1424 - 1433.
[Abstract] [Full Text] [PDF]

Home page
 Behav Cogn Neurosci RevHome page
A. C. Spector and S. P. Travers
The representation of taste quality in the Mammalian nervous system.
Behav Cogn Neurosci Rev, September 1, 2005; 4(3): 143 - 191.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
T. C. Pritchard, E. M. Edwards, C. A. Smith, K. G. Hilgert, A. M. Gavlick, T. D. Maryniak, G. J. Schwartz, and T. R. Scott
Gustatory Neural Responses in the Medial Orbitofrontal Cortex of the Old World Monkey
J. Neurosci., June 29, 2005; 25(26): 6047 - 6056.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
M. Kadohisa, E. T. Rolls, and J. V. Verhagen
Neuronal Representations of Stimuli in the Mouth: The Primate Insular Taste Cortex, Orbitofrontal Cortex and Amygdala
Chem Senses, June 1, 2005; 30(5): 401 - 419.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
G. Deco and E. T. Rolls
Synaptic and Spiking Dynamics underlying Reward Reversal in the Orbitofrontal Cortex
Cereb Cortex, January 1, 2005; 15(1): 15 - 30.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
E. T. Rolls
Taste and Related Systems in Primates Including Humans
Chem Senses, January 1, 2005; 30(suppl_1): i76 - i77.
[Full Text] [PDF]

Home page
 Chem SensesHome page
T. R. Scott, E. M. Edwards, C. A. Smith, K. G. Hilgert, G. J. Schwartz, and T. C. Pritchard
Medial Orbitofrontal Cortex: Its Role in Mediating Satiety in the Macaque
Chem Senses, January 1, 2005; 30(suppl_1): i190 - i190.
[Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. V. Verhagen, M. Kadohisa, and E. T. Rolls
Primate Insular/Opercular Taste Cortex: Neuronal Representations of the Viscosity, Fat Texture, Grittiness, Temperature, and Taste of Foods
J Neurophysiol, September 1, 2004; 92(3): 1685 - 1699.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M. Inoue, A. Mikami, I. Ando, and H. Tsukada
Functional Brain Mapping of the Macaque Related to Spatial Working Memory as Revealed by PET
Cereb Cortex, January 1, 2004; 14(1): 106 - 119.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. T. Rolls, J. V. Verhagen, and M. Kadohisa
Representations of the Texture of Food in the Primate Orbitofrontal Cortex: Neurons Responding to Viscosity, Grittiness, and Capsaicin
J Neurophysiol, December 1, 2003; 90(6): 3711 - 3724.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M.L. Kringelbach, J. O'Doherty, E.T. Rolls, and C. Andrews
Activation of the Human Orbitofrontal Cortex to a Liquid Food Stimulus is Correlated with its Subjective Pleasantness
Cereb Cortex, October 1, 2003; 13(10): 1064 - 1071.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. V. Verhagen, E. T. Rolls, and M. Kadohisa
Neurons in the Primate Orbitofrontal Cortex Respond to Fat Texture Independently of Viscosity
J Neurophysiol, September 1, 2003; 90(3): 1514 - 1525.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I. E.T. de Araujo, M. L. Kringelbach, E. T. Rolls, and F. McGlone
Human Cortical Responses to Water in the Mouth, and the Effects of Thirst
J Neurophysiol, September 1, 2003; 90(3): 1865 - 1876.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. T. Rolls, K. Inoue, and A. Browning
Activity of Primate Subgenual Cingulate Cortex Neurons Is Related to Sleep
J Neurophysiol, July 1, 2003; 90(1): 134 - 142.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I.E.T. de Araujo, M. L. Kringelbach, E. T. Rolls, and P. Hobden
Representation of Umami Taste in the Human Brain
J Neurophysiol, July 1, 2003; 90(1): 313 - 319.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
E.T. Rolls, J. O'Doherty, M.L. Kringelbach, S. Francis, R. Bowtell, and F. McGlone
Representations of Pleasant and Painful Touch in the Human Orbitofrontal and Cingulate Cortices
Cereb Cortex, March 1, 2003; 13(3): 308 - 317.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. T. Rolls, N. C. Aggelopoulos, and F. Zheng
The Receptive Fields of Inferior Temporal Cortex Neurons in Natural Scenes
J. Neurosci., January 1, 2003; 23(1): 339 - 348.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. H. Zald, M. C. Hagen, and J. V. Pardo
Neural Correlates of Tasting Concentrated Quinine and Sugar Solutions
J Neurophysiol, February 1, 2002; 87(2): 1068 - 1075.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
D. M. Small, R. J. Zatorre, A. Dagher, A. C. Evans, and M. Jones-Gotman
Changes in brain activity related to eating chocolate: From pleasure to aversion
Brain, September 1, 2001; 124(9): 1720 - 1733.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. S. Morris and R. J. Dolan
Involvement of Human Amygdala and Orbitofrontal Cortex in Hunger-Enhanced Memory for Food Stimuli
J. Neurosci., July 15, 2001; 21(14): 5304 - 5310.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
E. T. Rolls
The Rules of Formation of the Olfactory Representations Found in the Orbitofrontal Cortex Olfactory Areas in Primates
Chem Senses, June 1, 2001; 26(5): 595 - 604.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
D. M. Small, R. J. Zatorre, and M. Jones-Gotman
Changes in Taste Intensity Perception Following Anterior Temporal Lobe Removal in Humans
Chem Senses, May 1, 2001; 26(4): 425 - 432.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. O'Doherty, E. T. Rolls, S. Francis, R. Bowtell, and F. McGlone
Representation of Pleasant and Aversive Taste in the Human Brain
J Neurophysiol, March 1, 2001; 85(3): 1315 - 1321.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Tremblay and W. Schultz
Reward-Related Neuronal Activity During Go-Nogo Task Performance in Primate Orbitofrontal Cortex
J Neurophysiol, April 1, 2000; 83(4): 1864 - 1876.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
E. T. Rolls
The Representation of Umami Taste in the Taste Cortex
J. Nutr., April 1, 2000; 130(4): 960 - 960.
[Abstract] [Full Text]

Home page
 Cereb CortexHome page
W. Schultz, L. Tremblay, and J. R. Hollerman
Reward Processing in Primate Orbitofrontal Cortex and Basal Ganglia
Cereb Cortex, March 1, 2000; 10(3): 272 - 283.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
E. T. Rolls
The Orbitofrontal Cortex and Reward
Cereb Cortex, March 1, 2000; 10(3): 284 - 294.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. T. Rolls, H. D. Critchley, A. S. Browning, I. Hernadi, and L. Lenard
Responses to the Sensory Properties of Fat of Neurons in the Primate Orbitofrontal Cortex
J. Neurosci., February 15, 1999; 19(4): 1532 - 1540.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. M. Small, M. Jones-Gotman, R. J. Zatorre, M. Petrides, and A. C. Evans
A Role for the Right Anterior Temporal Lobe in Taste Quality Recognition
J. Neurosci., July 1, 1997; 17(13): 5136 - 5142.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online