| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Neurophysiology, Vol 65, Issue 6 1452-1463, Copyright © 1991 by APS
ARTICLES |
M. E. Frank
Department of BioStructure and Function, School of Dental Medicine, University of Connecticut Health Center, Farmington 06030.
1. Taste sensibilities of neurons in mammalian glossopharyngeal nerves have been inadequately studied, although they innervate the majority of taste buds and may provide unique taste information. 2. Extracellular responses of glossopharyngeal neural units to taste stimuli infused into foliate or vallate papillae were recorded in anesthetized rats. A 0.3-ml/min infusion of stimuli into papillae resulted in short-latency, 5-s nerve-impulse rates that approached 10 times the response rates observed using less invasive means of stimulation. 3. Sucrose, Na saccharin, NaCl, NH4Cl, KCl, HCl, citric acid, acetic acid, MgSO4, and quinine.HCl were effective stimuli for glossopharyngeal neurons at concentrations that have behavioral significance. 4. Response spectra for individual neural units with either foliate or vallate receptive fields fell into three clusters. Forty-six percent were A units that responded most strongly to acids and chloride salts, NH4Cl being the most effective; neither quinine nor sucrose was effective. Twenty-three percent were S units that responded to sugars and saccharin; quinine, salts, and acids were not effective. Thirty-one percent were Q units that responded to quinine; neither NaCl, HCl, nor sucrose was effective stimulus for these fragile units. 5. Glossopharyngeal A neural units were more sensitive to 1 mM HCl than were electrolyte-sensitive H units of the chorda tympani, although both respond generally to salts and acids. Units relatively specific for sodium salts (N units), which are common in the chorda tympani nerve, were not found in the glossopharyngeal nerve, which explains losses in sodium-specific behavior after cutting only the chorda tympani nerve. 6. Q units were the only glossopharyngeal neural units that responded significantly to quinine, and units with similar response spectra do not occur in the chorda tympani nerve. Q units probably mediate aversive reflexes to quinine that are eliminated by cutting only the glossopharyngeal nerve. Glossopharyngeal S neural units were more sensitive to sucrose and are more common than their counterparts in the chorda tympani, although it is not known how they might compare with sugar-sensitive units in the greater superficial petrosal nerve. 7. These data strongly suggest that posterior taste bud fields innervated by the glossopharyngeal nerve are specialized for functions different from those of anterior taste bud fields innervated by the facial nerve.
This article has been cited by other articles:
|
|
 |
|
  J.-Y. Chen and P. M. Di Lorenzo Responses to Binary Taste Mixtures in the Nucleus of the Solitary Tract: Neural Coding With Firing Rate J Neurophysiol, May 1, 2008; 99(5): 2144 - 2157. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Grover and M. E. Frank Regional Specificity of Chlorhexidine Effects on Taste Perception Chem Senses, April 1, 2008; 33(4): 311 - 318. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Merigo, D. Benati, M. Galie, C. Crescimanno, F. Osculati, and A. Sbarbati Immunohistochemical Localization of Cystic Fibrosis Transmembrane Regulator and Clara Cell Secretory Protein in Taste Receptor Cells of Rat Circumvallate Papillae Chem Senses, March 1, 2008; 33(3): 231 - 241. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Breza, K. S. Curtis, and R. J. Contreras Monosodium Glutamate but not Linoleic Acid Differentially Activates Gustatory Neurons in the Rat Geniculate Ganglion Chem Senses, November 1, 2007; 32(9): 833 - 846. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Accolla, B. Bathellier, C. C. H. Petersen, and A. Carleton Differential Spatial Representation of Taste Modalities in the Rat Gustatory Cortex J. Neurosci., February 7, 2007; 27(6): 1396 - 1404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. C. Geran and S. P. Travers Single Neurons in the Nucleus of the Solitary Tract Respond Selectively to Bitter Taste Stimuli J Neurophysiol, November 1, 2006; 96(5): 2513 - 2527. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. Lemon and D. V. Smith Neural Representation of Bitter Taste in the Nucleus of the Solitary Tract J Neurophysiol, December 1, 2005; 94(6): 3719 - 3729. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. C. Spector and S. P. Travers The representation of taste quality in the Mammalian nervous system. Behav Cogn Neurosci Rev, September 1, 2005; 4(3): 143 - 191. [Abstract] [PDF]
|
|
|
|
 |
|
 S. I. Sollars and D. L. Hill In vivo recordings from rat geniculate ganglia: taste response properties of individual greater superficial petrosal and chorda tympani neurones J. Physiol., May 1, 2005; 564(3): 877 - 893. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. St. John and J. D. Boughter Jr The Contribution of Taste Bud Populations to Bitter Avoidance in Mouse Strains Differentially Sensitive to Sucrose Octa-acetate and Quinine Chem Senses, November 1, 2004; 29(9): 775 - 795. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. Lemon, S. M. Brasser, and D. V. Smith Alcohol Activates a Sucrose-Responsive Gustatory Neural Pathway J Neurophysiol, July 1, 2004; 92(1): 536 - 544. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. M. Di Lorenzo, C. H. Lemon, and C. G. Reich Dynamic Coding of Taste Stimuli in the Brainstem: Effects of Brief Pulses of Taste Stimuli on Subsequent Taste Responses J. Neurosci., October 1, 2003; 23(26): 8893 - 8902. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. H. Lemon and P. M. Di Lorenzo Effects of Electrical Stimulation of the Chorda Tympani Nerve on Taste Responses in the Nucleus of the Solitary Tract J Neurophysiol, November 1, 2002; 88(5): 2477 - 2489. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. C. Geran, M. Garcea, and A. C. Spector Transecting the gustatory branches of the facial nerve impairs NH4Cl vs. KCl discrimination in rats Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2002; 283(3): R739 - R747. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Danilova, Y. Danilov, T. Roberts, J.-M. Tinti, C. Nofre, and G. Hellekant Sense of Taste in a New World Monkey, the Common Marmoset: Recordings From the Chorda Tympani and Glossopharyngeal Nerves J Neurophysiol, August 1, 2002; 88(2): 579 - 594. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Lin, T. Ogura, and S. C. Kinnamon Acid-Activated Cation Currents in Rat Vallate Taste Receptor Cells J Neurophysiol, July 1, 2002; 88(1): 133 - 141. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Spector and S. L. Kopka Rats Fail to Discriminate Quinine from Denatonium: Implications for the Neural Coding of Bitter-Tasting Compounds J. Neurosci., March 1, 2002; 22(5): 1937 - 1941. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Goto, M. Komai, H. Suzuki, and Y. Furukawa Long-Term Zinc Deficiency Decreases Taste Sensitivity in Rats J. Nutr., February 1, 2001; 131(2): 305 - 310. [Abstract] [Full Text]
|
|
|
|
|
|
T. Koga and R. M. Bradley Biophysical Properties and Responses to Neurotransmitters of Petrosal and Geniculate Ganglion Neurons Innervating the Tongue J Neurophysiol, September 1, 2000; 84(3): 1404 - 1413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Eylam, M. Garcea, and A. C. Spector Glossopharyngeal Nerve Transection Does Not Alter Taste Reactivity to Sucrose Conditioned to be Aversive Chem Senses, August 1, 2000; 25(4): 423 - 428. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Ninomiya, K. Nakashima, A. Fukuda, H. Nishino, T. Sugimura, A. Hino, V. Danilova, and G. Hellekant Responses to Umami Substances in Taste Bud Cells Innervated by the Chorda Tympani and Glossopharyngeal Nerves J. Nutr., April 1, 2000; 130(4): 950 - 950. [Abstract] [Full Text]
|
|
|
|
|
|
S. L. Kopka, L. C. Geran, and A. C. Spector Functional status of the regenerated chorda tympani nerve as assessed in a salt taste discrimination task Am J Physiol Regulatory Integrative Comp Physiol, March 1, 2000; 278(3): R720 - R731. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Lundy Jr. and R. J. Contreras Gustatory Neuron Types in Rat Geniculate Ganglion J Neurophysiol, December 1, 1999; 82(6): 2970 - 2988. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. E. Dinkins and S. P. Travers Altered Taste Responses in Adult NST After Neonatal Chorda Tympani Denervation J Neurophysiol, November 1, 1999; 82(5): 2565 - 2578. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Daikoku, I. Morisaki, Y. Ogawa, T. Maeda, K. Kurisu, and S. Wakisaka Immunohistochemical Localization of Carbonic Anhydrase Isozyme II in the Gustatory Epithelium of the Adult Rat Chem Senses, June 1, 1999; 24(3): 255 - 261. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Danilova, T. Roberts, and G. Hellekant Responses of Single Taste Fibers and Whole Chorda Tympani and Glossopharyngeal Nerve in the Domestic Pig, Sus scrofa Chem Senses, June 1, 1999; 24(3): 301 - 316. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. T. King, S. P. Travers, N. E. Rowland, M. Garcea, and A. C. Spector Glossopharyngeal Nerve Transection Eliminates Quinine-Stimulated Fos-Like Immunoreactivity in the Nucleus of the Solitary Tract: Implications for a Functional Topography of Gustatory Nerve Input in Rats J. Neurosci., April 15, 1999; 19(8): 3107 - 3121. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. E. Stewart, V. Lyall, G. M. Feldman, G. L. Heck, and J. A. DeSimone Acid-induced responses in hamster chorda tympani and intracellular pH tracking by taste receptor cells Am J Physiol Cell Physiol, July 1, 1998; 275(1): C227 - C238. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. St. John and A. C. Spector Behavioral Discrimination between Quinine and KCl Is Dependent on Input from the Seventh Cranial Nerve: Implications for the Functional Roles of the Gustatory Nerves in Rats J. Neurosci., June 1, 1998; 18(11): 4353 - 4362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Spector and S. J. St. John Role of taste in the microstructure of quinine ingestion by rats Am J Physiol Regulatory Integrative Comp Physiol, June 1, 1998; 274(6): R1687 - R1703. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Hanamori, T. Kunitake, K. Kato, and H. Kannan Responses of Neurons in the Insular Cortex to Gustatory, Visceral, and Nociceptive Stimuli in Rats J Neurophysiol, May 1, 1998; 79(5): 2535 - 2545. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nishijo, T. Uwano, R. Tamura, and T. Ono Gustatory and Multimodal Neuronal Responses in the Amygdala During Licking and Discrimination of Sensory Stimuli in Awake Rats J Neurophysiol, January 1, 1998; 79(1): 21 - 36. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Nishijo and R. Norgren Parabrachial Neural Coding of Taste Stimuli in Awake Rats J Neurophysiol, November 1, 1997; 78(5): 2254 - 2268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. B. Halsell and S. P. Travers Anterior and Posterior Oral Cavity Responsive Neurons Are Differentially Distributed Among Parabrachial Subnuclei in Rat J Neurophysiol, August 1, 1997; 78(2): 920 - 938. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Boughter Jr., D. W. Pumplin, C. Yu, R. C. Christy, and D. V. Smith Differential Expression of alpha -Gustducin in Taste Bud Populations of the Rat and Hamster J. Neurosci., April 15, 1997; 17(8): 2852 - 2858. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Hellekant, V. Danilova, and Y. Ninomiya Primate Sense of Taste: Behavioral and Single Chorda Tympani and Glossopharyngeal Nerve Fiber Recordings in the Rhesus Monkey, Macaca mulatta J Neurophysiol, February 1, 1997; 77(2): 978 - 993. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
