JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 67: 1031-1056, 1992;
0022-3077/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Recanzone, G. H.
Right arrow Articles by Dinse, H. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Recanzone, G. H.
Right arrow Articles by Dinse, H. R.

Journal of Neurophysiology, Vol 67, Issue 5 1031-1056, Copyright © 1992 by APS

ARTICLES

Topographic reorganization of the hand representation in cortical area 3b owl monkeys trained in a frequency-discrimination task

G. H. Recanzone, M. M. Merzenich, W. M. Jenkins, K. A. Grajski and H. R. Dinse
Coleman Laboratory, Department of Physiology, University of California, San Francisco 94143-0732.

1. Adult owl monkeys were trained to detect differences in the frequency of a tactile flutter-vibration stimulus above a 20-Hz standard. All stimuli were delivered to a constant skin site restricted to a small part of a segment of one finger. The frequency-difference discrimination performance of all but one of these monkeys improved progressively with training. 2. The distributed responses of cortical neurons ("maps") of the hand surfaces were defined in detail in somatosensory cortical area 3b. Representations of trained hands were compared with those of the opposite, untrained hand, and to the area 3b representations of hands in a second set of monkeys that were stimulated tactually in the same manner while these monkeys were attending to auditory stimuli (passive stimulation controls). 3. The cortical representations of the trained hands were substantially more complex in topographic detail than the representations of unstimulated hands or of passively stimulated control hands. 4. In all well-trained monkeys the representations of the restricted skin location trained in the behavioral task were significantly (1.5 to greater than 3 times) greater in area than were the representations of equivalent skin locations on control digits. However, the overall extents of the representations of behaviorally stimulated fingers were not larger than those of control fingers in the same hemisphere, or in opposite hemisphere controls. 5. The receptive fields representing the trained skin were significantly larger than receptive fields representing control digits in all but one trained monkey. The largest receptive fields were centered in the zone of representation of the behaviorally engaged skin, but they were not limited to it. Large receptive fields were recorded in a 1- to 2-mm-wide zone in the area 3b maps of trained hands. 6. Receptive-field sizes were also statistically significantly larger on at least one adjacent, untrained digit when compared with the receptive fields recorded on the homologous digit of the opposite hand. 7. There was an increase in the percent overlaps of receptive fields in the cortical zone of representation of the trained skin. A significant number of receptive fields were centered on the behaviorally trained skin site. 8. The effects of increased topographic complexity, increased representation of the trained skin location, increased receptive-field size, and increased receptive-field overlap were not observed in the representations of the untrained hands in these same monkeys. Only modest increases in topographic complexity were recorded in the representations of passively stimulated hands, and no effects on receptive-field size or overlap were noted.(ABSTRACT TRUNCATED AT 400 WORDS)


This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
R. D. Lane, C. P. Pluto, C. L. Kenmuir, N. L. Chiaia, and R. D. Mooney
Does Reorganization in the Cuneate Nucleus Following Neonatal Forelimb Amputation Influence Development of Anomalous Circuits Within the Somatosensory Cortex?
J Neurophysiol, February 1, 2008; 99(2): 866 - 875.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
R. O. Duncan and G. M. Boynton
Tactile Hyperacuity Thresholds Correlate with Finger Maps in Primary Somatosensory Cortex (S1)
Cereb Cortex, December 1, 2007; 17(12): 2878 - 2891.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
O. Hoffken, M. Veit, F. Knossalla, S. Lissek, B. Bliem, P. Ragert, H. R. Dinse, and M. Tegenthoff
Sustained increase of somatosensory cortex excitability by tactile coactivation studied by paired median nerve stimulation in humans correlates with perceptual gain
J. Physiol., October 15, 2007; 584(2): 463 - 471.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. C. Puckett, P. K. Pandya, R. Moucha, W. Dai, and M. P. Kilgard
Plasticity in the Rat Posterior Auditory Field Following Nucleus Basalis Stimulation
J Neurophysiol, July 1, 2007; 98(1): 253 - 265.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Leingartner, S. Thuret, T. T. Kroll, S.-J. Chou, J. L. Leasure, F. H. Gage, and D. D. M. O'Leary
Cortical area size dictates performance at modality-specific behaviors
PNAS, March 6, 2007; 104(10): 4153 - 4158.
[Abstract] [Full Text] [PDF]

Home page
 Neurorehabil Neural RepairHome page
K. M. Friel, S. Barbay, S. B. Frost, E. J. Plautz, A. M. Stowe, N. Dancause, E. V. Zoubina, and R. J. Nudo
Effects of a Rostral Motor Cortex Lesion on Primary Motor Cortex Hand Representation Topography in Primates
Neurorehabil Neural Repair, January 1, 2007; 21(1): 51 - 61.
[Abstract] [PDF]

Home page
 Learn. Mem.Home page
R. Galvez, A. P. Weible, and J. F. Disterhoft
Cortical barrel lesions impair whisker-CS trace eyeblink conditioning
Learn. Mem., January 1, 2007; 14(1-2): 94 - 100.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. Pleger, C. C. Ruff, F. Blankenburg, S. Bestmann, K. Wiech, K. E. Stephan, A. Capilla, K. J. Friston, and R. J. Dolan
Neural Coding of Tactile Decisions in the Human Prefrontal Cortex
J. Neurosci., November 29, 2006; 26(48): 12596 - 12601.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. B. Moldakarimov, J. L. McClelland, and G. B. Ermentrout
A homeostatic rule for inhibitory synapses promotes temporal sharpening and cortical reorganization
PNAS, October 31, 2006; 103(44): 16526 - 16531.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
A. A. Karim, A. Schuler, Y. L. Hegner, E. Friedel, and B. Godde
Facilitating effect of 15-Hz repetitive transcranial magnetic stimulation on tactile perceptual learning.
J. Cogn. Neurosci., September 1, 2006; 18(9): 1577 - 1585.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. W. Mahncke, B. B. Connor, J. Appelman, O. N. Ahsanuddin, J. L. Hardy, R. A. Wood, N. M. Joyce, T. Boniske, S. M. Atkins, and M. M. Merzenich
Memory enhancement in healthy older adults using a brain plasticity-based training program: A randomized, controlled study
PNAS, August 15, 2006; 103(33): 12523 - 12528.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. Ramanathan, J. M. Conner, and M. H. Tuszynski
A form of motor cortical plasticity that correlates with recovery of function after brain injury
PNAS, July 25, 2006; 103(30): 11370 - 11375.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. Galvez, C. Weiss, A. P. Weible, and J. F. Disterhoft
Vibrissa-signaled eyeblink conditioning induces somatosensory cortical plasticity.
J. Neurosci., May 31, 2006; 26(22): 6062 - 6068.
[Abstract] [Full Text] [PDF]

Home page
 Chem SensesHome page
C. Kobayashi, L. M. Kennedy, and B. P. Halpern
Experience-Induced Changes in Taste Identification of Monosodium Glutamate (MSG) Are Reversible
Chem Senses, May 1, 2006; 31(4): 301 - 306.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. Pleger, F. Blankenburg, S. Bestmann, C. C. Ruff, K. Wiech, K. E. Stephan, K. J. Friston, and R. J. Dolan
Repetitive Transcranial Magnetic Stimulation-Induced Changes in Sensorimotor Coupling Parallel Improvements of Somatosensation in Humans
J. Neurosci., February 15, 2006; 26(7): 1945 - 1952.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. Fernandez-Ruiz, R. Diaz, P. Moreno-Briseno, A. Campos-Romo, and R. Ojeda
Rapid Topographical Plasticity of the Visuomotor Spatial Transformation
J. Neurosci., February 15, 2006; 26(7): 1986 - 1990.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. T. Blake, F. Strata, R. Kempter, and M. M. Merzenich
Experience-Dependent Plasticity in S1 Caused by Noncoincident Inputs
J Neurophysiol, September 1, 2005; 94(3): 2239 - 2250.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
L. M. Chen, R. M. Friedman, and A. W. Roe
Optical Imaging of SI Topography in Anesthetized and Awake Squirrel Monkeys
J. Neurosci., August 17, 2005; 25(33): 7648 - 7659.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. W. Hickmott
Changes in Intrinsic Properties of Pyramidal Neurons in Adult Rat S1 During Cortical Reorganization
J Neurophysiol, July 1, 2005; 94(1): 501 - 511.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. Brechmann and H. Scheich
Hemispheric shifts of sound representation in auditory cortex with conceptual listening
Cereb Cortex, May 1, 2005; 15(5): 578 - 587.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
J. P. Hunter, J. Katz, and K. D. Davis
Dissociation of phantom limb phenomena from stump tactile spatial acuity and sensory thresholds
Brain, February 1, 2005; 128(2): 308 - 320.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
K. Rosenkranz and J. C Rothwell
The effect of sensory input and attention on the sensorimotor organization of the hand area of the human motor cortex
J. Physiol., November 15, 2004; 561(1): 307 - 320.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M. Brown, D. R.F. Irvine, and V. N. Park
Perceptual Learning on an Auditory Frequency Discrimination Task by Cats: Association with Changes in Primary Auditory Cortex
Cereb Cortex, September 1, 2004; 14(9): 952 - 965.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
J. M. Zacks, P. Michelon, J. M. Vettel, and J. G. Ojemann
Functional reorganization of spatial transformations after a parietal lesion
Neurology, July 27, 2004; 63(2): 287 - 292.
[Abstract] [Full Text] [PDF]

Home page
 Clin RehabilHome page
A. J Turton and S. R Butler
A multiple case design experiment to investigate the performance and neural effects of a programme for training hand function after stroke
Clinical Rehabilitation, July 1, 2004; 18(7): 754 - 763.
[Abstract] [PDF]

Home page
 J. Neurophysiol.Home page
C. M. Butefisch, V. Khurana, L. Kopylev, and L. G. Cohen
Enhancing Encoding of a Motor Memory in the Primary Motor Cortex By Cortical Stimulation
J Neurophysiol, May 1, 2004; 91(5): 2110 - 2116.
[Abstract] [Full Text] [PDF]

Home page
 NeuroscientistHome page
T. Elbert and B. Rockstroh
Reorganization of Human Cerebral Cortex: The Range of Changes Following Use and Injury
Neuroscientist, April 1, 2004; 10(2): 129 - 141.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
T. Yang and J. H. R. Maunsell
The Effect of Perceptual Learning on Neuronal Responses in Monkey Visual Area V4
J. Neurosci., February 18, 2004; 24(7): 1617 - 1626.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. F. Salazar, C. Kayser, and P. Konig
Effects of Training on Neuronal Activity and Interactions in Primary and Higher Visual Cortices in the Alert Cat
J. Neurosci., February 18, 2004; 24(7): 1627 - 1636.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. Hodzic, R. Veit, A. A. Karim, M. Erb, and B. Godde
Improvement and Decline in Tactile Discrimination Behavior after Cortical Plasticity Induced by Passive Tactile Coactivation
J. Neurosci., January 14, 2004; 24(2): 442 - 446.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
M. Atienza, J. L. Cantero, and R. Stickgold
Posttraining Sleep Enhances Automaticity in Perceptual Discrimination
J. Cogn. Neurosci., January 1, 2004; 16(1): 53 - 64.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
K. R. Huxlin and T. Pasternak
Training-induced Recovery of Visual Motion Perception after Extrastriate Cortical Damage in the Adult Cat
Cereb Cortex, January 1, 2004; 14(1): 81 - 90.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Bao, E. F. Chang, J. D. Davis, K. T. Gobeske, and M. M. Merzenich
Progressive Degradation and Subsequent Refinement of Acoustic Representations in the Adult Auditory Cortex
J. Neurosci., November 26, 2003; 23(34): 10765 - 10775.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
H. Thai-Van, C. Micheyl, B. C. J. Moore, and L. Collet
Enhanced frequency discrimination near the hearing loss cut-off: a consequence of central auditory plasticity induced by cochlear damage?
Brain, October 1, 2003; 126(10): 2235 - 2245.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
V. Rema, M. Armstrong-James, and F. F. Ebner
Experience-Dependent Plasticity Is Impaired in Adult Rat Barrel Cortex after Whiskers Are Unused in Early Postnatal Life
J. Neurosci., January 1, 2003; 23(1): 358 - 366.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. Schwartz, P. Maquet, and C. Frith
Neural correlates of perceptual learning: A functional MRI study of visual texture discrimination
PNAS, December 24, 2002; 99(26): 17137 - 17142.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. A. Harris, C. Miniussi, I. M. Harris, and M. E. Diamond
Transient Storage of a Tactile Memory Trace in Primary Somatosensory Cortex
J. Neurosci., October 1, 2002; 22(19): 8720 - 8725.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. T. Blake, F. Strata, A. K. Churchland, and M. M. Merzenich
Neural correlates of instrumental learning in primary auditory cortex
PNAS, July 23, 2002; 99(15): 10114 - 10119.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
F. Vega-Bermudez and K. O. Johnson
Spatial acuity after digit amputation
Brain, June 1, 2002; 125(6): 1256 - 1264.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
M. Atienza, J. L. Cantero, and E. Dominguez-Marin
The Time Course of Neural Changes Underlying Auditory Perceptual Learning
Learn. Mem., May 1, 2002; 9(3): 138 - 150.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. C. Catania and M. S. Remple
Somatosensory cortex dominated by the representation of teeth in the naked mole-rat brain
PNAS, April 16, 2002; 99(8): 5692 - 5697.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
G. M. Ghose, T. Yang, and J. H. R. Maunsell
Physiological Correlates of Perceptual Learning in Monkey V1 and V2
J Neurophysiol, April 1, 2002; 87(4): 1867 - 1888.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
H. Thai-Van, C. Micheyl, A. Norena, and L. Collet
Local improvement in auditory frequency discrimination is associated with hearing-loss slope in subjects with cochlear damage
Brain, February 1, 2002; 125(3): 524 - 537.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. M. Chen, R. M. Friedman, B. M. Ramsden, R. H. LaMotte, and A. W. Roe
Fine-Scale Organization of SI (Area 3b) in the Squirrel Monkey Revealed With Intrinsic Optical Imaging
J Neurophysiol, December 1, 2001; 86(6): 3011 - 3029.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Ahissar
Perceptual training: A tool for both modifying the brain and exploring it
PNAS, October 9, 2001; 98(21): 11842 - 11843.
[Full Text] [PDF]

Home page
 Cereb CortexHome page
K. J. Huffman and L. Krubitzer
Area 3a: Topographic Organization and Cortical Connections in Marmoset Monkeys
Cereb Cortex, September 1, 2001; 11(9): 849 - 867.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
M. Tervaniemi, M. Rytkonen, E. Schroger, R. J. Ilmoniemi, and R. Naatanen
Superior Formation of Cortical Memory Traces for Melodic Patterns in Musicians
Learn. Mem., September 1, 2001; 8(5): 295 - 300.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. P. Kilgard, P. K. Pandya, J. Vazquez, A. Gehi, C. E. Schreiner, and M. M. Merzenich
Sensory Input Directs Spatial and Temporal Plasticity in Primary Auditory Cortex
J Neurophysiol, July 1, 2001; 86(1): 326 - 338.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
E. Diesch and T. Luce
Topographic and Temporal Indices of Vowel Spectral Envelope Extraction in the Human Auditory Cortex
J. Cogn. Neurosci., September 1, 2000; 12(5): 878 - 893.
[Abstract] [Full Text]

Home page
 NeurologyHome page
R. W. V. Boven, R. H. Hamilton, T. Kauffman, J. P. Keenan, and A. Pascual-Leone
Tactile spatial resolution in blind Braille readers
Neurology, June 27, 2000; 54(12): 2230 - 2236.
[Abstract] [Full Text] [PDF]

Home page
 J Hand Surg Eur VolHome page
G. LUNDBORG
Brain Plasticity and Hand Surgery: an Overview
J Hand Surg Eur Vol., June 1, 2000; 25(3): 242 - 252.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
B. Godde, B. Stauffenberg, F. Spengler, and H. R. Dinse
Tactile Coactivation-Induced Changes in Spatial Discrimination Performance
J. Neurosci., February 15, 2000; 20(4): 1597 - 1604.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. A. Wilson
Odor Specificity of Habituation in the Rat Anterior Piriform Cortex
J Neurophysiol, January 1, 2000; 83(1): 139 - 145.
[Abstract] [Full Text] [PDF]

Home page
 Neurorehabil Neural RepairHome page
K. Sathian, A. I. Greenspan, and S. L. Wolf
Doing It with Mirrors: A Case Study of a Novel Approach to Neurorehabilitation
Neurorehabil Neural Repair, January 1, 2000; 14(1): 73 - 76.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
C. Braun, R. Schweizer, T. Elbert, N. Birbaumer, and E. Taub
Differential Activation in Somatosensory Cortex for Different Discrimination Tasks
J. Neurosci., January 1, 2000; 20(1): 446 - 450.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. Naito, H. H. Ehrsson, S. Geyer, K. Zilles, and P. E. Roland
Illusory Arm Movements Activate Cortical Motor Areas: A Positron Emission Tomography Study
J. Neurosci., July 15, 1999; 19(14): 6134 - 6144.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
C. Xerri, M. M. Merzenich, W. Jenkins, and S. Santucci
Representational Plasticity in Cortical Area 3b Paralleling Tactual-motor Skill Acquisition in Adult Monkeys
Cereb Cortex, April 1, 1999; 9(3): 264 - 276.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I. Salimi, T. Brochier, and A. M. Smith
Neuronal Activity in Somatosensory Cortex of Monkeys Using a Precision Grip. I. Receptive Fields and Discharge Patterns
J Neurophysiol, February 1, 1999; 81(2): 825 - 834.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
W. Huang, M. Armstrong-James, V. Rema, M. E. Diamond, and F. F. Ebner
Contribution of Supragranular Layers to Sensory Processing and Plasticity in Adult Rat Barrel Cortex
J Neurophysiol, December 1, 1998; 80(6): 3261 - 3271.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
B. A. Dosher and Z.-L. Lu
Perceptual learning reflects external noise filtering and internal noise reduction through channel reweighting
PNAS, November 10, 1998; 95(23): 13988 - 13993.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
L. M. Vaina, J. W. Belliveau, E. B. d. Roziers, and T. A. Zeffiro
Neural systems underlying learning and representation of global motion
PNAS, October 13, 1998; 95(21): 12657 - 12662.
[Abstract] [Full Text] [PDF]

Home page