Journal of Neurophysiology, Vol 67, Issue 6 1691-1694, Copyright © 1992 by APS

ARTICLES

Artificial electrical synapses in oscillatory networks

A. A. Sharp, L. F. Abbott and E. Marder
Physics Department, Brandeis University, Waltham, Massachusetts 02254.

1. We use an electronic circuit to artificially electrically couple neurons. 2. Strengthening the coupling between an oscillating neuron and a hyperpolarized, passive neuron can either increase or decrease the frequency of the oscillator depending on the properties of the oscillator. 3. The result of electrically coupling two neuronal oscillators depends on the membrane potentials, intrinsic properties of the neurons, and the coupling strength. 4. The interplay between chemical inhibitory synapses and electrical synapses can be studied by creating both chemical and electrical synapses between two cultured neurons and by artificially strengthening the electrical synapse between the ventricular dilator and one pyloric dilator neuron of the stomatogastric ganglion.

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