Journal of Neurophysiology, Vol 68, Issue 5 1913-1916, Copyright © 1992 by APS

ARTICLES

Saccade initiation and latency deficits after combined lesions of the frontal and posterior eye fields in monkeys

J. C. Lynch
Department of Anatomy, University of Mississippi Medical Center, Jackson 39216.

1. Monkeys were trained to perform horizontal visually guided saccades. Latency was measured before and after bilateral lesions of the frontal eye field (FEF) and after combined lesions of both the FEF and the posterior eye field. Destruction of either of these regions alone causes only modest deficits of eye movement, but destruction of both together produces profound oculomotor impairment. The results support the proposal that purposeful eye movements are controlled by a distributed corticocortical network that includes nodes in frontal and parieto-occipital regions.

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