JN Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 69: 1797-1809, 1993;
0022-3077/93 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wallace, M. T.
Right arrow Articles by Stein, B. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wallace, M. T.
Right arrow Articles by Stein, B. E.

Journal of Neurophysiology, Vol 69, Issue 6 1797-1809, Copyright © 1993 by APS

ARTICLES

Converging influences from visual, auditory, and somatosensory cortices onto output neurons of the superior colliculus

M. T. Wallace, M. A. Meredith and B. E. Stein
Department of Physiology, Medical College of Virginia, Richmond 23298.

1. Physiological methods were used to examine the pattern of inputs from different sensory cortices onto individual superior colliculus neurons. 2. Visual, auditory, and somatosensory influences from anterior ectosylvian sulcus (AES) and visual influences from lateral suprasylvian (LS) cortex were found to converge onto individual multisensory neurons in the cat superior colliculus. An excellent topographic relationship was found between the different sensory cortices and their target neurons in the superior colliculus. 3. Corticotectal inputs were derived solely from unimodal neurons. Multisensory neurons in AES and LS were not antidromically activated from the superior colliculus. 4. Orthodromic and antidromic latencies were consistent with monosynaptic corticotectal inputs arising from LS and the three subdivisions of AES (SIV, Field AES, and AEV). 5. Superior colliculus neurons that received convergent cortical inputs formed a principal component of the tecto-reticulospinal tract. Thus there appears to be extensive cortical control over the output neurons through which the superior colliculus mediates attentive and orientation behaviors. 6. Two other multisensory circuits were identified. A population of multisensory superior colliculus neurons was found, which neither received convergent cortical input nor projected into the tecto-reticulo-spinal tract. In addition, multisensory neurons in AES and LS proved to be independent of the superior colliculus (i.e., they were not corticotectal). While it is likely that these three distinct multisensory neural circuits have different functional roles, their constituent neurons appear to integrate their various sensory inputs in much the same way.


This article has been cited by other articles:


Home page
 Cereb CortexHome page
B. L. Allman, R. E. Bittencourt-Navarrete, L. P. Keniston, A. E. Medina, M. Y. Wang, and M. A. Meredith
Do Cross-Modal Projections Always Result in Multisensory Integration?
Cereb Cortex, September 1, 2008; 18(9): 2066 - 2076.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
V. Fuentes-Santamaria, J. C. Alvarado, B. E. Stein, and J. G. McHaffie
Cortex Contacts both Output Neurons and Nitrergic Interneurons in the Superior Colliculus: Direct and Indirect Routes for Multisensory Integration
Cereb Cortex, July 1, 2008; 18(7): 1640 - 1652.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. C. Alvarado, T. R. Stanford, J. W. Vaughan, and B. E. Stein
Cortex Mediates Multisensory But Not Unisensory Integration in Superior Colliculus
J. Neurosci., November 21, 2007; 27(47): 12775 - 12786.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. N. Carriere, D. W. Royal, T. J. Perrault, S. P. Morrison, J. W. Vaughan, B. E. Stein, and M. T. Wallace
Visual Deprivation Alters the Development of Cortical Multisensory Integration
J Neurophysiol, November 1, 2007; 98(5): 2858 - 2867.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. Noesselt, J. W. Rieger, M. A. Schoenfeld, M. Kanowski, H. Hinrichs, H.-J. Heinze, and J. Driver
Audiovisual Temporal Correspondence Modulates Human Multisensory Superior Temporal Sulcus Plus Primary Sensory Cortices
J. Neurosci., October 17, 2007; 27(42): 11431 - 11441.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. K. Bizley, F. R. Nodal, V. M. Bajo, I. Nelken, and A. J. King
Physiological and Anatomical Evidence for Multisensory Interactions in Auditory Cortex
Cereb Cortex, September 1, 2007; 17(9): 2172 - 2189.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. C. Alvarado, J. W. Vaughan, T. R. Stanford, and B. E. Stein
Multisensory Versus Unisensory Integration: Contrasting Modes in the Superior Colliculus
J Neurophysiol, May 1, 2007; 97(5): 3193 - 3205.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. G. Lomber, S. Malhotra, and J. M. Sprague
Restoration of Acoustic Orienting Into a Cortically Deaf Hemifield by Reversible Deactivation of the Contralesional Superior Colliculus: The Acoustic "Sprague Effect"
J Neurophysiol, February 1, 2007; 97(2): 979 - 993.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. T. Wallace, B. N. Carriere, T. J. Perrault Jr, J. W. Vaughan, and B. E. Stein
The Development of Cortical Multisensory Integration.
J. Neurosci., November 15, 2006; 26(46): 11844 - 11849.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M. F. S. Rushworth, T. E. J. Behrens, and H. Johansen-Berg
Connection Patterns Distinguish 3 Regions of Human Parietal Cortex
Cereb Cortex, October 1, 2006; 16(10): 1418 - 1430.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Molholm, P. Sehatpour, A. D. Mehta, M. Shpaner, M. Gomez-Ramirez, S. Ortigue, J. P. Dyke, T. H. Schwartz, and J. J. Foxe
Audio-Visual Multisensory Integration in Superior Parietal Lobule Revealed by Human Intracranial Recordings
J Neurophysiol, August 1, 2006; 96(2): 721 - 729.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
W. Jiang, H. Jiang, and B. E. Stein
Neonatal Cortical Ablation Disrupts Multisensory Development in Superior Colliculus
J Neurophysiol, March 1, 2006; 95(3): 1380 - 1396.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. R. Stanford, S. Quessy, and B. E. Stein
Evaluating the Operations Underlying Multisensory Integration in the Cat Superior Colliculus
J. Neurosci., July 13, 2005; 25(28): 6499 - 6508.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
T. J. Perrault Jr., J. W. Vaughan, B. E. Stein, and M. T. Wallace
Superior Colliculus Neurons Use Distinct Operational Modes in the Integration of Multisensory Stimuli
J Neurophysiol, May 1, 2005; 93(5): 2575 - 2586.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. T. Wallace, T. J. Perrault Jr, W. D. Hairston, and B. E. Stein
Visual Experience Is Necessary for the Development of Multisensory Integration
J. Neurosci., October 27, 2004; 24(43): 9580 - 9584.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Malhotra, A. J. Hall, and S. G. Lomber
Cortical Control of Sound Localization in the Cat: Unilateral Cooling Deactivation of 19 Cerebral Areas
J Neurophysiol, September 1, 2004; 92(3): 1625 - 1643.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. P. Zwiers, H. Versnel, and A. J. Van Opstal
Involvement of Monkey Inferior Colliculus in Spatial Hearing
J. Neurosci., April 28, 2004; 24(17): 4145 - 4156.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
L. R. Dehner, L. P. Keniston, H. R. Clemo, and M. A. Meredith
Cross-modal Circuitry Between Auditory and Somatosensory Areas of the Cat Anterior Ectosylvian Sulcal Cortex: A 'New' Inhibitory Form of Multisensory Convergence
Cereb Cortex, April 1, 2004; 14(4): 387 - 403.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
T. J. Perrault Jr., J. W. Vaughan, B. E. Stein, and M. T. Wallace
Neuron-Specific Response Characteristics Predict the Magnitude of Multisensory Integration
J Neurophysiol, December 1, 2003; 90(6): 4022 - 4026.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. J. Anastasio and P. E. Patton
A Two-Stage Unsupervised Learning Algorithm Reproduces Multisensory Enhancement in a Neural Network Model of the Corticotectal System
J. Neurosci., July 30, 2003; 23(17): 6713 - 6727.
[Abstract] [Full Text] [PDF]

Home page
 Neural Comput.Home page
P. E. Patton and T. J. Anastasio
Modeling Cross-Modal Enhancement and Modality-Specific Suppression in Multisensory Neurons
Neural Comput., April 1, 2003; 15(4): 783 - 810.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
W. Jiang, H. Jiang, and B. E. Stein
Two Corticotectal Areas Facilitate Multisensory Orientation Behavior
J. Cogn. Neurosci., November 1, 2002; 14(8): 1240 - 1255.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. Fort, C. Delpuech, J. Pernier, and M.-H. Giard
Dynamics of Cortico-subcortical Cross-modal Operations Involved in Audio-visual Object Detection in Humans
Cereb Cortex, October 1, 2002; 12(10): 1031 - 1039.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
G. A. Calvert
Crossmodal Processing in the Human Brain: Insights from Functional Neuroimaging Studies
Cereb Cortex, December 1, 2001; 11(12): 1110 - 1123.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. T. Wallace and B. E. Stein
Sensory and Multisensory Responses in the Newborn Monkey Superior Colliculus
J. Neurosci., November 15, 2001; 21(22): 8886 - 8894.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
S. Zangenehpour and A. Chaudhuri
Neural Activity Profiles of the Neocortex and Superior Colliculus after Bimodal Sensory Stimulation
Cereb Cortex, October 1, 2001; 11(10): 924 - 935.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
S. Kennett, M. Eimer, C. Spence, and J. Driver
Tactile-Visual Links in Exogenous Spatial Attention Under Different Postures: Convergent Evidence from Psychophysics and ERPs
J. Cogn. Neurosci., May 1, 2001; 13(4): 462 - 478.
[Abstract] [Full Text]

Home page
 J. Neurophysiol.Home page
W. Jiang, M. T. Wallace, H. Jiang, J. W. Vaughan, and B. E. Stein
Two Cortical Areas Mediate Multisensory Integration in Superior Colliculus Neurons
J Neurophysiol, February 1, 2001; 85(2): 506 - 522.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. T. Wallace and B. E. Stein
Onset of Cross-Modal Synthesis in the Neonatal Superior Colliculus is Gated by the Development of Cortical Influences
J Neurophysiol, June 1, 2000; 83(6): 3578 - 3582.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Sommer and R. H. Wurtz
Composition and Topographic Organization of Signals Sent From the Frontal Eye Field to the Superior Colliculus
J Neurophysiol, April 1, 2000; 83(4): 1979 - 2001.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
M. H. Giard and F. Peronnet
Auditory-Visual Integration during Multimodal Object Recognition in Humans: A Behavioral and Electrophysiological Study
J. Cogn. Neurosci., September 1, 1999; 11(5): 473 - 490.
[Abstract] [Full Text]

Home page
 J. Neurophysiol.Home page
M. T. Wallace, M. A. Meredith, and B. E. Stein
Multisensory Integration in the Superior Colliculus of the Alert Cat
J Neurophysiol, August 1, 1998; 80(2): 1006 - 1010.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. C. Kadunce, J. W. Vaughan, M. T. Wallace, G. Benedek, and B. E. Stein
Mechanisms of Within- and Cross-Modality Suppression in the Superior Colliculus
J Neurophysiol, December 1, 1997; 78(6): 2834 - 2847.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. T. Wallace and B. E. Stein
Development of Multisensory Neurons and Multisensory Integration in Cat Superior Colliculus
J. Neurosci., April 1, 1997; 17(7): 2429 - 2444.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online