JN Miami Valley Hospital
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 77: 944-961, 1997;
0022-3077/97 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bremmer, F.
Right arrow Articles by Hoffmann, K.-P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bremmer, F.
Right arrow Articles by Hoffmann, K.-P.

The Journal of Neurophysiology Vol. 77 No. 2 February 1997, pp. 944-961
Copyright ©1997 The American Physiological Society

Eye Position Effects in Monkey Cortex. I. Visual and Pursuit-Related Activity in Extrastriate Areas MT and MST

F. Bremmer, U. J. Ilg, A. Thiele, C. Distler, and K.-P. Hoffmann

Department of Zoology and Neurobiology, Ruhr University Bochum, D-44780 Bochum, Germany

Bremmer, F., U. J. Ilg, A. Thiele, C. Distler, and K.-P. Hoffmann. Eye position effects in monkey cortex. I. Visual and pursuit-related activity in extrastriate areas MT and MST. J. Neurophysiol. 77: 944-961, 1997. We studied the effect of eye position on visual and pursuit-related activity in neurons in the superior temporal sulcus of the macaque monkey. Altogether, 109 neurons from the middle temporal area (area MT) and the medial superior temporal area (area MST) were tested for influence of eye position on their stimulus-driven response in a fixation paradigm. In this paradigm the monitored eye position signal was superimposed onto the stimulus control signal while the monkey fixated at different locations on a screen. This setup guaranteed that an optimized stimulus was moved across the receptive field at the same retinal location for all fixation locations. For 61% of the MT neurons and 82% of the MST neurons the stimulus-induced response was modulated by the position of the eyes in the orbit. Directional selectivity was not influenced by eye position. One hundred sixty-eight neurons exhibited direction-specific responses during smooth tracking eye movements and were tested in a pursuit paradigm. Here the monkey had to track a target that started to move in the preferred direction with constant speed from five different locations on the screen in random order. Pursuit-related activity was modulated by eye position in 78% of the MT neurons as well as in 80% of the MST neurons tested. Neuronal activity varied linearly as a function of both horizontal and vertical eye position for most of the neurons tested in both areas, i.e., two-dimensional regression planes could be approximated to the responses of most of the neurons. The directions of the gradients of these regression planes correlated neither with the preferred stimulus direction tested in the fixation paradigm nor with the preferred tracking direction in the pursuit paradigm. Eighty-six neurons were tested with both the fixation and the pursuit paradigms. The directions of the gradients of the regression planes fit to the responses in both paradigms tended to correlate with each other, i.e., for more than two thirds of the neurons the angular difference between both directions was less than ±90°. The modulatory effect of the position of the eyes in the orbit proved to balance out at the population level for neurons in areas MT and MST, tested with the fixation as well as the pursuit paradigm. Results are discussed in light of the hypothesis of an ongoing coordinate transformation of the incoming sensory signals into a nonretinocentric representation of the visual field.




This article has been cited by other articles:


Home page
 J. Neurosci.Home page
J. L. Gardner, E. P. Merriam, J. A. Movshon, and D. J. Heeger
Maps of Visual Space in Human Occipital Cortex Are Retinotopic, Not Spatiotopic
J. Neurosci., April 9, 2008; 28(15): 3988 - 3999.
[Abstract] [Full Text] [PDF]

Home page
 Neural Comput.Home page
C. R. Cassanello and V. P. Ferrera
Visual remapping by vector subtraction: analysis of multiplicative gain field models.
Neural Comput., September 1, 2007; 19(9): 2353 - 2386.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
M. Tanaka
Spatiotemporal Properties of Eye Position Signals in the Primate Central Thalamus
Cereb Cortex, July 1, 2007; 17(7): 1504 - 1515.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C. R. Fetsch, S. Wang, Y. Gu, G. C. DeAngelis, and D. E. Angelaki
Spatial Reference Frames of Visual, Vestibular, and Multimodal Heading Signals in the Dorsal Subdivision of the Medial Superior Temporal Area
J. Neurosci., January 17, 2007; 27(3): 700 - 712.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
R. Philipp, C. Distler, and K.-P. Hoffmann
A Motion-sensitive Area in Ferret Extrastriate Visual Cortex: an Analysis in Pigmented and Albino Animals
Cereb Cortex, June 1, 2006; 16(6): 779 - 790.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. Goossens, S. P. Dukelow, R. S. Menon, T. Vilis, and A. V. van den Berg
Representation of Head-Centric Flow in the Human Motion Complex
J. Neurosci., May 24, 2006; 26(21): 5616 - 5627.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. K. Porter, R. R. Metzger, and J. M. Groh
Representation of Eye Position in Primate Inferior Colliculus
J Neurophysiol, March 1, 2006; 95(3): 1826 - 1842.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Gu, P. V. Watkins, D. E. Angelaki, and G. C. DeAngelis
Visual and Nonvisual Contributions to Three-Dimensional Heading Selectivity in the Medial Superior Temporal Area
J. Neurosci., January 4, 2006; 26(1): 73 - 85.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
O. A. Mullette-Gillman, Y. E. Cohen, and J. M. Groh
Eye-Centered, Head-Centered, and Complex Coding of Visual and Auditory Targets in the Intraparietal Sulcus
J Neurophysiol, October 1, 2005; 94(4): 2331 - 2352.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. K. Churchland and S. G. Lisberger
Relationship Between Extraretinal Component of Firing Rate and Eye Speed in Area MST of Macaque Monkeys
J Neurophysiol, October 1, 2005; 94(4): 2416 - 2426.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. K. Churchland and S. G. Lisberger
Discharge Properties of MST Neurons That Project to the Frontal Pursuit Area in Macaque Monkeys
J Neurophysiol, August 1, 2005; 94(2): 1084 - 1090.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
F. Bremmer
Navigation in space - the role of the macaque ventral intraparietal area
J. Physiol., July 1, 2005; 566(1): 29 - 35.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
T. Akao, M. J. Mustari, J. Fukushima, S. Kurkin, and K. Fukushima
Discharge Characteristics of Pursuit Neurons in MST During Vergence Eye Movements
J Neurophysiol, May 1, 2005; 93(5): 2415 - 2434.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. R. Metzger, O. A. Mullette-Gillman, A. M. Underhill, Y. E. Cohen, and J. M. Groh
Auditory Saccades From Different Eye Positions in the Monkey: Implications for Coordinate Transformations
J Neurophysiol, October 1, 2004; 92(4): 2622 - 2627.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
J. Lewald, I. G. Meister, J. Weidemann, and R. Topper
Involvement of the Superior Temporal Cortex and the Occipital Cortex in Spatial Hearing: Evidence from Repetitive Transcranial Magnetic Stimulation
J. Cogn. Neurosci., June 1, 2004; 16(5): 828 - 838.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. Genovesio and S. Ferraina
Integration of Retinal Disparity and Fixation-Distance Related Signals Toward an Egocentric Coding of Distance in the Posterior Parietal Cortex of Primates
J Neurophysiol, June 1, 2004; 91(6): 2670 - 2684.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. K. Murphy and K. D. Miller
Multiplicative Gain Changes Are Induced by Excitation or Inhibition Alone
J. Neurosci., November 5, 2003; 23(31): 10040 - 10051.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
U. J. Ilg and P. Thier
Visual Tracking Neurons in Primate Area MST Are Activated by Smooth-Pursuit Eye Movements of an "Imaginary" Target
J Neurophysiol, September 1, 2003; 90(3): 1489 - 1502.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Petit and M. S. Beauchamp
Neural Basis of Visually Guided Head Movements Studied With fMRI
J Neurophysiol, May 1, 2003; 89(5): 2516 - 2527.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. V. Shenoy, J. A. Crowell, and R. A. Andersen
Pursuit Speed Compensation in Cortical Area MSTd
J Neurophysiol, November 1, 2002; 88(5): 2630 - 2647.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. N. Eskandar and J. A. Assad
Distinct Nature of Directional Signals Among Parietal Cortical Areas During Visual Guidance
J Neurophysiol, October 1, 2002; 88(4): 1777 - 1790.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. F.X. DeSouza, S. P. Dukelow, and T. Vilis
Eye Position Signals Modulate Early Dorsal and Ventral Visual Areas
Cereb Cortex, September 1, 2002; 12(9): 991 - 997.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Tanaka and S. G. Lisberger
Role of Arcuate Frontal Cortex of Monkeys in Smooth Pursuit Eye Movements. I. Basic Response Properties to Retinal Image Motion and Position
J Neurophysiol, June 1, 2002; 87(6): 2684 - 2699.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K.-P. Hoffmann, F. Bremmer, A. Thiele, and C. Distler
Directional Asymmetry of Neurons in Cortical Areas MT and MST Projecting to the NOT-DTN in Macaques
J Neurophysiol, April 1, 2002; 87(4): 2113 - 2123.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
M. T. Froehler and C. J. Duffy
Cortical Neurons Encoding Path and Place: Where You Go Is Where You Are
Science, March 29, 2002; 295(5564): 2462 - 2465.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
H. L. O'Brien, S. J. Tetewsky, L. M. Avery, L. A. Cushman, W. Makous, and C. J. Duffy
Visual Mechanisms of Spatial Disorientation in Alzheimer's Disease
Cereb Cortex, November 1, 2001; 11(11): 1083 - 1092.
[Abstract] [Full Text] [PDF]

Home page
 Arch Gen PsychiatryHome page
G. A. O'Driscoll, C. Benkelfat, P. S. Florencio, A.-L. V. G. Wolff, R. Joober, S. Lal, and A. C. Evans
Neural Correlates of Eye Tracking Deficits in First-degree Relatives of Schizophrenic Patients: A Positron Emission Tomography Study
Arch Gen Psychiatry, December 1, 1999; 56(12): 1127 - 1134.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Petit and J. V. Haxby
Functional Anatomy of Pursuit Eye Movements in Humans as Revealed by fMRI
J Neurophysiol, July 1, 1999; 82(1): 463 - 471.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. V. Shenoy, D. C. Bradley, and R. A. Andersen
Influence of Gaze Rotation on the Visual Response of Primate MSTd Neurons
J Neurophysiol, June 1, 1999; 81(6): 2764 - 2786.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. Nakamura, H. H. Chung, M.S.A. Graziano, and C. G. Gross
Dynamic Representation of Eye Position in the Parieto-Occipital Sulcus
J Neurophysiol, May 1, 1999; 81(5): 2374 - 2385.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
W. K. Page and C. J. Duffy
MST Neuronal Responses to Heading Direction During Pursuit Eye Movements
J Neurophysiol, February 1, 1999; 81(2): 596 - 610.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. Boussaoud, C. Jouffrais, and F. Bremmer
Eye Position Effects on the Neuronal Activity of Dorsal Premotor Cortex in the Macaque Monkey
J Neurophysiol, September 1, 1998; 80(3): 1132 - 1150.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. A. Perrone and L. S. Stone
Emulating the Visual Receptive-Field Properties of MST Neurons with a Template Model of Heading Estimation
J. Neurosci., August 1, 1998; 18(15): 5958 - 5975.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online