JN Information on EB 2010
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 79: 2408-2415, 1998;
0022-3077/98 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (16)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Stumpner, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Stumpner, A.

The Journal of Neurophysiology Vol. 79 No. 5 May 1998, pp. 2408-2415
Copyright ©1998 The American Physiological Society

Picrotoxin Eliminates Frequency Selectivity of an Auditory Interneuron in a Bushcricket

Andreas Stumpner

I. Zoologisches Institut, D-37073 Gottingen, Germany

Stumpner, Andreas. Picrotoxin eliminates frequency selectivity of an auditory interneuron in a bushcricket. J. Neurophysiol. 79: 2408-2415, 1998. AN1, an auditory interneuron in the bushcricket Ancistrura nigrovittata, is narrowly tuned to the male song frequency (~15 kHz). It receives pronounced inhibitory input at frequencies below and, more prominently, above this fundamental frequency. It is also subject to side-dependent inhibition producing asymmetric response functions for left- and right-side stimulation. In addition, intensity-response functions of AN1 peak as stimulus intensities increase. Application of the GABAA channel-blocker picrotoxin eliminates all subthreshold inhibitory postsynaptic potentials, revealing underlying excitation that is particularly obvious in the high-frequency range. Excitatory thresholds close to the song frequency remain unchanged by picrotoxin. Thus a specifically tuned neuron is shown to become broadly tuned after elimination of frequency-dependent inhibition. Although average maximum response strength is increased by 150% after picrotoxin application, at male song frequencies a slight reduction of the responses is still present at high intensities. Side-dependent inhibition remains largely unaffected by picrotoxin, suggesting that side- and frequency-dependent inhibitions are caused by different transmitters from different neurons.




This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
J. D. Triblehorn and J. Schul
Sensory-Encoding Differences Contribute to Species-Specific Call Recognition Mechanisms
J Neurophysiol, September 1, 2009; 102(3): 1348 - 1357.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
A Stumpner
An interneurone of unusual morphology is tuned to the female song frequency in the bushcricket Ancistrura nigrovittata (Orthoptera, Phaneropteridae)
J. Exp. Biol., January 8, 1999; 202(15): 2071 - 2081.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online