JN Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 80: 172-185, 1998;
0022-3077/98 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kautz, D.
Right arrow Articles by Wagner, H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kautz, D.
Right arrow Articles by Wagner, H.

The Journal of Neurophysiology Vol. 80 No. 1 July 1998, pp. 172-185
Copyright ©1998 The American Physiological Society

GABAergic Inhibition Influences Auditory Motion-Direction Sensitivity in Barn Owls

Dirk Kautz and Hermann Wagner

Max-Planck-Institut für biologische Kybernetik, D-72076 Tübingen, Germany and Institut für Zoologie, Technische Universität München, D-85747 Garching, Germany

Kautz, Dirk and Hermann Wagner. GABAergic inhibition influences auditory motion-direction sensitivity in barn owls. J. Neurophysiol. 80: 172-185, 1998. Many neurons in the barn owl's inferior colliculus (IC) exhibit auditory motion-direction sensitivity (MDS), i.e., they respond more to motion of a sound source in one direction than to motion in the opposite direction. We investigated the cellular mechanisms underlying the phenomenon of auditory MDS by microiontophoretically applying gamma -aminobutyric acid (GABA) or the GABA-antagonist bicuculline methiodide (BMI) while recording from neurons in the owl's midbrain. In most cases GABA reduced the overall firing rate, whereas BMI increased it. In addition, 29% of the motion-direction-sensitive cells completely lost their selectivity for the direction of auditory movement during administration of BMI. It had been proposed that auditory MDS in the owl is due to inhibition. The present results show that GABAergic inhibition plays a role in the strengthening of MDS. We discuss the data within the framework of the acoustic motion detector and with respect to microiontophoretic studies on visual motion detection and on inhibitory mechanisms in the inferior colliculus.




This article has been cited by other articles:


Home page
 J. Neurosci.Home page
H. Wagner, A. Asadollahi, P. Bremen, F. Endler, K. Vonderschen, and M. von Campenhausen
Distribution of Interaural Time Difference in the Barn Owl's Inferior Colliculus in the Low- and High-Frequency Ranges
J. Neurosci., April 11, 2007; 27(15): 4191 - 4200.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. H. Wu, C. L. Ma, and J. B. Kelly
Contribution of AMPA, NMDA, and GABAA Receptors to Temporal Pattern of Postsynaptic Responses in the Inferior Colliculus of the Rat
J. Neurosci., May 12, 2004; 24(19): 4625 - 4634.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online