| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 80 No. 3 September 1998,
pp. 1577-1583
Copyright ©1998 The American Physiological Society
RAPID COMMUNICATION
Centre de Recherche en Sciences Neurologiques, Departement de Physiologie, Université de Montréal, Montréal, Québec, H3C 3J7 Canada
Sergio, Lauren E. and John F. Kalaska. Changes in the temporal pattern of primary motor cortex activity in a directional isometric force versus limb movement task. J. Neurophysiol. 80: 1577-1583, 1998. We recorded the activity of 75 proximal-arm-related cells in caudal primary motor cortex (MI) while a monkey generated either isometric forces or limb movements against an inertial load. The forces and movements were in eight directions in a horizontal plane. The isometric force generated at the hand increased monotonically in the direction of the target force level. The force exerted against the load in the movement task was more complex, including a transient decelerative phase during the movement as the hand approached the target. Electromyographic (EMG) activity of proximal-arm muscles reflected the task-dependent changes in dynamics, showing a ramp increase in activity during the isometric task and a reciprocal triphasic burst pattern in the movement task. A sliding 50-ms window analysis showed that the directionality of the EMG, when expressed in hand-centered spatial coordinates, remained stable throughout the isometric ramp but often showed a significant transient shift during the limb movements. Many cells in M1 showed corresponding significant changes in activity pattern and instantaneous directionality between the two tasks. This momentary dissociation of discharge from the directional kinematics of hand displacement is evidence that the activity of many single proximal-arm related M1 cells is not coupled only to the direction and velocity of hand motion.
This article has been cited by other articles:
|
|
 |
|
  A. Messinger, M. A. Lebedev, J. D. Kralik, and S. P. Wise Multitasking of Attention and Memory Functions in the Primate Prefrontal Cortex J. Neurosci., April 29, 2009; 29(17): 5640 - 5653. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Pruszynski, A. M. Coderre, T. P. Lillicrap, and I. Kurtzer Temporal Encoding of Movement in Motor Cortical Neurons J. Neurosci., September 19, 2007; 27(38): 10076 - 10077. [Full Text] [PDF]
|
|
|
|
 |
|
 I. Kurtzer and T. M. Herter Contrasting Interpretations of the Nonuniform Distribution of Preferred Directions Within Primary Motor Cortex J Neurophysiol, June 1, 2007; 97(6): 4390 - 4390. [Full Text] [PDF]
|
|
|
|
|
|
N. G. Hatsopoulos, Q. Xu, and Y. Amit Encoding of Movement Fragments in the Motor Cortex J. Neurosci., May 9, 2007; 27(19): 5105 - 5114. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Yu, C. Kemere, G. Santhanam, A. Afshar, S. I. Ryu, T. H. Meng, M. Sahani, and K. V. Shenoy Mixture of Trajectory Models for Neural Decoding of Goal-Directed Movements J Neurophysiol, May 1, 2007; 97(5): 3763 - 3780. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yamamoto, M. Kawato, S. Kotosaka, and S. Kitazawa Encoding of Movement Dynamics by Purkinje Cell Simple Spike Activity During Fast Arm Movements Under Resistive and Assistive Force Fields J Neurophysiol, February 1, 2007; 97(2): 1588 - 1599. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. Morrow, L. R. Jordan, and L. E. Miller Direct Comparison of the Task-Dependent Discharge of M1 in Hand Space and Muscle Space J Neurophysiol, February 1, 2007; 97(2): 1786 - 1798. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Guigon, P. Baraduc, and M. Desmurget Computational Motor Control: Redundancy and Invariance J Neurophysiol, January 1, 2007; 97(1): 331 - 347. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Hamel-Paquet, L. E. Sergio, and J. F. Kalaska Parietal Area 5 Activity Does Not Reflect the Differential Time-Course of Motor Output Kinetics During Arm-Reaching and Isometric-Force Tasks J Neurophysiol, June 1, 2006; 95(6): 3353 - 3370. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Carmena, M. A. Lebedev, C. S. Henriquez, and M. A. L. Nicolelis Stable Ensemble Performance with Single-Neuron Variability during Reaching Movements in Primates J. Neurosci., November 16, 2005; 25(46): 10712 - 10716. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Sergio, C. Hamel-Paquet, and J. F. Kalaska Motor Cortex Neural Correlates of Output Kinematics and Kinetics During Isometric-Force and Arm-Reaching Tasks J Neurophysiol, October 1, 2005; 94(4): 2353 - 2378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Lebedev, J. M. Carmena, J. E. O'Doherty, M. Zacksenhouse, C. S. Henriquez, J. C. Principe, and M. A. L. Nicolelis Cortical Ensemble Adaptation to Represent Velocity of an Artificial Actuator Controlled by a Brain-Machine Interface J. Neurosci., May 11, 2005; 25(19): 4681 - 4693. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. S. Thomas, D. M. Corcos, and Z. Hasan Kinematic and Kinetic Constraints on Arm, Trunk, and Leg Segments in Target-Reaching Movements J Neurophysiol, January 1, 2005; 93(1): 352 - 364. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Shah, A. H. Fagg, and A. G. Barto Cortical Involvement in the Recruitment of Wrist Muscles J Neurophysiol, June 1, 2004; 91(6): 2445 - 2456. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. E. Vaillancourt, J. Prodoehl, L. Verhagen Metman, R. A. Bakay, and D. M. Corcos Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease Brain, March 1, 2004; 127(3): 491 - 504. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Paninski, M. R. Fellows, N. G. Hatsopoulos, and J. P. Donoghue Spatiotemporal Tuning of Motor Cortical Neurons for Hand Position and Velocity J Neurophysiol, January 1, 2004; 91(1): 515 - 532. [Abstract] [Full Text]
|
|
|
|
|
|
P. Cisek, D. J. Crammond, and J. F. Kalaska Neural Activity in Primary Motor and Dorsal Premotor Cortex In Reaching Tasks With the Contralateral Versus Ipsilateral Arm J Neurophysiol, February 1, 2003; 89(2): 922 - 942. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Sergio and J. F. Kalaska Systematic Changes in Motor Cortex Cell Activity With Arm Posture During Directional Isometric Force Generation J Neurophysiol, January 1, 2003; 89(1): 212 - 228. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Ajemian, D. Bullock, and S. Grossberg A Model of Movement Coordinates in the Motor Cortex: Posture-dependent Changes in the Gain and Direction of Single Cell Tuning Curves Cereb Cortex, December 1, 2001; 11(12): 1124 - 1135. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Ajemian, D. Bullock, and S. Grossberg Kinematic Coordinates In Which Motor Cortical Cells Encode Movement Direction J Neurophysiol, November 1, 2000; 84(5): 2191 - 2203. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. D MacKinnon and J. C Rothwell Time-varying changes in corticospinal excitability accompanying the triphasic EMG pattern in humans J. Physiol., November 1, 2000; 528(3): 633 - 645. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Messier and J. F. Kalaska Covariation of Primate Dorsal Premotor Cell Activity With Direction and Amplitude During a Memorized-Delay Reaching Task J Neurophysiol, July 1, 2000; 84(1): 152 - 165. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Thoroughman and R. Shadmehr Electromyographic Correlates of Learning an Internal Model of Reaching Movements J. Neurosci., October 1, 1999; 19(19): 8573 - 8588. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Kakei, D. S. Hoffman, and P. L. Strick Muscle and Movement Representations in the Primary Motor Cortex Science, September 24, 1999; 285(5436): 2136 - 2139. [Abstract] [Full Text]
|
|
|
|
|
|
E. Nakano, H. Imamizu, R. Osu, Y. Uno, H. Gomi, T. Yoshioka, and M. Kawato Quantitative Examinations of Internal Representations for Arm Trajectory Planning: Minimum Commanded Torque Change Model J Neurophysiol, May 1, 1999; 81(5): 2140 - 2155. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. S. Hoffman and P. L. Strick Step-Tracking Movements of the Wrist. IV. Muscle Activity Associated With Movements in Different Directions J Neurophysiol, January 1, 1999; 81(1): 319 - 333. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
