| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 81 No. 4 April 1999, pp. 1927-1938
Copyright ©1999 by the American Physiological Society
Department of Physiology, Tohoku University School of Medicine, Sendai 980-8575, Japan
Kurata, Kiyoshi and
Eiji Hoshi.
Reacquisition deficits in prism adaptation after muscimol
microinjection into the ventral premotor cortex of monkeys. A
small amount of muscimol (1 µl; concentration, 5 µg/µl) was
injected into the ventral and dorsal premotor cortex areas (PMv and
PMd, respectively) of monkeys, which then were required to perform a
visually guided reaching task. For the task, the monkeys were required
to reach for a target soon after it was presented on a screen. While
performing the task, the monkeys' eyes were covered with left 10°,
right 10°, or no wedge prisms, for a block of 50-100 trials. Without
the prisms, the monkeys reached the targets accurately. When the prisms
were placed, the monkeys initially misreached the targets because the
prisms displaced the visual field. Before the muscimol injection, the
monkeys adapted to the prisms in 10-20 trials, judging from the
horizontal distance between the target location and the point where the
monkey touched the screen. After muscimol injection into the PMv, the
monkeys lost the ability to readapt and touched the screen closer to
the location of the targets as seen through the prisms. This deficit
was observed at selective target locations, only when the targets were
shifted contralaterally to the injected hemisphere. When muscimol was injected into the PMd, no such deficits were observed. There were no
changes in the reaction and movement times induced by muscimol injections in either area. The results suggest that the PMv plays an
important role in motor learning, specifically in recalibrating visual
and motor coordinates.
This article has been cited by other articles:
|
|
 |
|
  N. Malfait, D. Y. Henriques, and P. L. Gribble Shape Distortion Produced by Isolated Mismatch Between Vision and Proprioception J Neurophysiol, January 1, 2008; 99(1): 231 - 243. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Simani, L. M. M. McGuire, and P. N. Sabes Visual-Shift Adaptation Is Composed of Separable Sensory and Task-Dependent Effects J Neurophysiol, November 1, 2007; 98(5): 2827 - 2841. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurata Laterality of Movement-Related Activity Reflects Transformation of Coordinates in Ventral Premotor Cortex and Primary Motor Cortex of Monkeys J Neurophysiol, October 1, 2007; 98(4): 2008 - 2021. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Cheng and P. N. Sabes Calibration of Visually Guided Reaching Is Driven by Error-Corrective Learning and Internal Dynamics J Neurophysiol, April 1, 2007; 97(4): 3057 - 3069. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Michel, L. Pisella, C. Prablanc, G. Rode, and Y. Rossetti Enhancing Visuomotor Adaptation by Reducing Error Signals: Single-step (Aware) versus Multiple-step (Unaware) Exposure to Wedge Prisms. J. Cogn. Neurosci., February 1, 2007; 19(2): 341 - 350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Yamamoto, D. S. Hoffman, and P. L. Strick Rapid and Long-Lasting Plasticity of Input-Output Mapping J Neurophysiol, November 1, 2006; 96(5): 2797 - 2801. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Hoshi and J. Tanji Differential Involvement of Neurons in the Dorsal and Ventral Premotor Cortex During Processing of Visual Signals for Action Planning J Neurophysiol, June 1, 2006; 95(6): 3596 - 3616. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.-H. Lee and P. van Donkelaar The human dorsal premotor cortex generates on-line error corrections during sensorimotor adaptation. J. Neurosci., March 22, 2006; 26(12): 3330 - 3334. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Pisella, Y. Rossetti, C. Michel, G. Rode, D. Boisson, D. Pelisson, and C. Tilikete Ipsidirectional impairment of prism adaptation after unilateral lesion of anterior cerebellum Neurology, July 12, 2005; 65(1): 150 - 152. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Ochiai, H. Mushiake, and J. Tanji Involvement of the Ventral Premotor Cortex in Controlling Image Motion of the Hand During Performance of a Target-capturing Task Cereb Cortex, July 1, 2005; 15(7): 929 - 937. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Morton and A. J. Bastian Prism Adaptation During Walking Generalizes to Reaching and Requires the Cerebellum J Neurophysiol, October 1, 2004; 92(4): 2497 - 2509. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. B. Schwartz, D. W. Moran, and G. A. Reina Differential Representation of Perception and Action in the Frontal Cortex Science, January 16, 2004; 303(5656): 380 - 383. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. B. Frost, S. Barbay, K. M. Friel, E. J. Plautz, and R. J. Nudo Reorganization of Remote Cortical Regions After Ischemic Brain Injury: A Potential Substrate for Stroke Recovery J Neurophysiol, June 1, 2003; 89(6): 3205 - 3214. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurata and E. Hoshi Movement-Related Neuronal Activity Reflecting the Transformation of Coordinates in the Ventral Premotor Cortex of Monkeys J Neurophysiol, December 1, 2002; 88(6): 3118 - 3132. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Martin, S. A. Norris, B. E. Greger, and W. T. Thach Dynamic Coordination of Body Parts During Prism Adaptation J Neurophysiol, October 1, 2002; 88(4): 1685 - 1694. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.F.S. Rushworth, K. A. Hadland, T. Paus, and P. K. Sipila Role of the Human Medial Frontal Cortex in Task Switching: A Combined fMRI and TMS Study J Neurophysiol, May 1, 2002; 87(5): 2577 - 2592. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Hoshi and J. Tanji Contrasting Neuronal Activity in the Dorsal and Ventral Premotor Areas During Preparation to Reach J Neurophysiol, February 1, 2002; 87(2): 1123 - 1128. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Fogassi, V. Gallese, G. Buccino, L. Craighero, L. Fadiga, and G. Rizzolatti Cortical mechanism for the visual guidance of hand grasping movements in the monkey: A reversible inactivation study Brain, March 1, 2001; 124(3): 571 - 586. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Clower and D. Boussaoud Selective Use of Perceptual Recalibration Versus Visuomotor Skill Acquisition J Neurophysiol, November 1, 2000; 84(5): 2703 - 2708. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurata, T. Tsuji, S. Naraki, M. Seino, and Y. Abe Activation of the Dorsal Premotor Cortex and Pre-Supplementary Motor Area of Humans During an Auditory Conditional Motor Task J Neurophysiol, September 1, 2000; 84(3): 1667 - 1672. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Hoshi, K. Shima, and J. Tanji Neuronal Activity in the Primate Prefrontal Cortex in the Process of Motor Selection Based on Two Behavioral Rules J Neurophysiol, April 1, 2000; 83(4): 2355 - 2373. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
