JN AJP: Advances in Physiology Education
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 82: 463-471, 1999;
0022-3077/99 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Petit, L.
Right arrow Articles by Haxby, J. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Petit, L.
Right arrow Articles by Haxby, J. V.

The Journal of Neurophysiology Vol. 82 No. 1 July 1999, pp. 463-471
Copyright ©1999 by the American Physiological Society

Functional Anatomy of Pursuit Eye Movements in Humans as Revealed by fMRI

Laurent Petit and James V. Haxby

Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, Maryland 20892

Petit, Laurent and James V. Haxby. Functional Anatomy of Pursuit Eye Movements in Humans as Revealed by fMRI. J. Neurophysiol. 82: 463-471, 1999.We have investigated the functional anatomy of pursuit eye movements in humans with functional magnetic imaging. The performance of pursuit eye movements induced activations in the cortical eye fields also activated during the execution of visually guided saccadic eye movements, namely in the precentral cortex [frontal eye field (FEF)], the medial superior frontal cortex (supplementary eye field), the intraparietal cortex (parietal eye field), and the precuneus, and at the junction of occipital and temporal cortex (MT/MST) cortex. Pursuit-related areas could be distinguished from saccade-related areas both in terms of spatial extent and location. Pursuit-related areas were smaller than their saccade-related counterparts, three of eight significantly so. The pursuit-related FEF was usually inferior to saccade-related FEF. Other pursuit-related areas were consistently posterior to their saccade-related counterparts. The current findings provide the first functional imaging evidence for a distinction between two parallel cortical systems that subserve pursuit and saccadic eye movements in humans.




This article has been cited by other articles:


Home page
 J. Neurosci.Home page
C. de Hemptinne, P. Lefevre, and M. Missal
Neuronal Bases of Directional Expectation and Anticipatory Pursuit
J. Neurosci., April 23, 2008; 28(17): 4298 - 4310.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
C. C. Ruff, S. Bestmann, F. Blankenburg, O. Bjoertomt, O. Josephs, N. Weiskopf, R. Deichmann, and J. Driver
Distinct Causal Influences of Parietal Versus Frontal Areas on Human Visual Cortex: Evidence from Concurrent TMS-fMRI
Cereb Cortex, April 1, 2008; 18(4): 817 - 827.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. Bartels, S. Zeki, and N. K. Logothetis
Natural Vision Reveals Regional Specialization to Local Motion and to Contrast-Invariant, Global Flow in the Human Brain
Cereb Cortex, March 1, 2008; 18(3): 705 - 717.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
A. S. Drew and P. van Donkelaar
The Contribution of the Human FEF and SEF to Smooth Pursuit Initiation
Cereb Cortex, November 1, 2007; 17(11): 2618 - 2624.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
J.-J. Orban de Xivry and P. Lefevre
Saccades and pursuit: two outcomes of a single sensorimotor process
J. Physiol., October 1, 2007; 584(1): 11 - 23.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Bakola, G. G. Gregoriou, A. K. Moschovakis, V. Raos, and H. E. Savaki
Saccade-Related Information in the Superior Temporal Motion Complex: Quantitative Functional Mapping in the Monkey
J. Neurosci., February 28, 2007; 27(9): 2224 - 2229.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
A. Lindner, T. Haarmeier, M. Erb, W. Grodd, and P. Thier
Cerebrocerebellar Circuits for the Perceptual Cancellation of Eye-movement-induced Retinal Image Motion.
J. Cogn. Neurosci., November 1, 2006; 18(11): 1899 - 1912.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. de Hemptinne, P. Lefevre, and M. Missal
Influence of Cognitive Expectation on the Initiation of Anticipatory and Visual Pursuit Eye Movements in the Rhesus Monkey
J Neurophysiol, June 1, 2006; 95(6): 3770 - 3782.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J. Goossens, S. P. Dukelow, R. S. Menon, T. Vilis, and A. V. van den Berg
Representation of Head-Centric Flow in the Human Motion Complex
J. Neurosci., May 24, 2006; 26(21): 5616 - 5627.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
J. T. Baker, G. H. Patel, M. Corbetta, and L. H. Snyder
Distribution of Activity Across the Monkey Cerebral Cortical Surface, Thalamus and Midbrain during Rapid, Visually Guided Saccades
Cereb Cortex, April 1, 2006; 16(4): 447 - 459.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C. Amiez, P. Kostopoulos, A.-S. Champod, and M. Petrides
Local morphology predicts functional organization of the dorsal premotor region in the human brain.
J. Neurosci., March 8, 2006; 26(10): 2724 - 2731.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. Gagnon, T. Paus, M.-H. Grosbras, G. B. Pike, and G. A. O'Driscoll
Transcranial Magnetic Stimulation of Frontal Oculomotor Regions during Smooth Pursuit
J. Neurosci., January 11, 2006; 26(2): 458 - 466.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J.-J. Orban de Xivry, S. J. Bennett, P. Lefevre, and G. R. Barnes
Evidence for Synergy Between Saccades and Smooth Pursuit During Transient Target Disappearance
J Neurophysiol, January 1, 2006; 95(1): 418 - 427.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. Kurata, K. R. Thulborn, and L. L. Firestone
The Cross-Modal Interaction Between Pain-Related and Saccade-Related Cerebral Activation: A Preliminary Study by Event-Related Functional Magnetic Resonance Imaging
Anesth. Analg., August 1, 2005; 101(2): 449 - 456.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Tanaka
Involvement of the Central Thalamus in the Control of Smooth Pursuit Eye Movements
J. Neurosci., June 22, 2005; 25(25): 5866 - 5876.
[Abstract] [Full Text] [PDF]

Home page
 NeuroscientistHome page
R. J. Krauzlis
The Control of Voluntary Eye Movements: New Perspectives
Neuroscientist, April 1, 2005; 11(2): 124 - 137.
[Abstract] [PDF]

Home page
 J. Neurophysiol.Home page
V. Della-Maggiore and A. R. McIntosh
Time Course of Changes in Brain Activity and Functional Connectivity Associated With Long-Term Adaptation to a Rotational Transformation
J Neurophysiol, April 1, 2005; 93(4): 2254 - 2262.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
F. P. de Lange, P. Hagoort, and I. Toni
Neural Topography and Content of Movement Representations
J. Cogn. Neurosci., January 1, 2005; 17(1): 97 - 112.
[Abstract] [Full Text] [PDF]

Home page
 J. Cogn. Neurosci.Home page
A. C. Nobre, J. T. Coull, P. Maquet, C. D. Frith, R. Vandenberghe, and M. M. Mesulam
Orienting Attention to Locations in Perceptual Versus Mental Representations
J. Cogn. Neurosci., March 1, 2004; 16(3): 363 - 373.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. J. Krauzlis
Recasting the Smooth Pursuit Eye Movement System
J Neurophysiol, February 1, 2004; 91(2): 591 - 603.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
C Brenneis, K Seppi, M Schocke, T Benke, G K Wenning, and W Poewe
Voxel based morphometry reveals a distinct pattern of frontal atrophy in progressive supranuclear palsy
J. Neurol. Neurosurg. Psychiatry, February 1, 2004; 75(2): 246 - 249.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Petit and M. S. Beauchamp
Neural Basis of Visually Guided Head Movements Studied With fMRI
J Neurophysiol, May 1, 2003; 89(5): 2516 - 2527.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
P. Maquet, S. Schwartz, R. Passingham, and C. Frith
Sleep-Related Consolidation of a Visuomotor Skill: Brain Mechanisms as Assessed by Functional Magnetic Resonance Imaging
J. Neurosci., February 15, 2003; 23(4): 1432 - 1440.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
H. Burton, A. Z. Snyder, J. B. Diamond, and M. E. Raichle
Adaptive Changes in Early and Late Blind: A fMRI Study of Verb Generation to Heard Nouns
J Neurophysiol, December 1, 2002; 88(6): 3359 - 3371.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
B. Luna, N. J. Minshew, K. E. Garver, N. A. Lazar, K. R. Thulborn, W. F. Eddy, and J. A. Sweeney
Neocortical system abnormalities in autism: An fMRI study of spatial working memory
Neurology, September 24, 2002; 59(6): 834 - 840.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Tanaka and S. G. Lisberger
Role of Arcuate Frontal Cortex of Monkeys in Smooth Pursuit Eye Movements. I. Basic Response Properties to Retinal Image Motion and Position
J Neurophysiol, June 1, 2002; 87(6): 2684 - 2699.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Tanaka and S. G. Lisberger
Enhancement of Multiple Components of Pursuit Eye Movement by Microstimulation in the Arcuate Frontal Pursuit Area in Monkeys
J Neurophysiol, February 1, 2002; 87(2): 802 - 818.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Ferraina, M. Pare, and R. H. Wurtz
Comparison of Cortico-Cortical and Cortico-Collicular Signals for the Generation of Saccadic Eye Movements
J Neurophysiol, February 1, 2002; 87(2): 845 - 858.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
C. Rosano, C. M. Krisky, J. S. Welling, W. F. Eddy, B. Luna, K. R. Thulborn, and J. A. Sweeney
Pursuit and Saccadic Eye Movement Subregions in Human Frontal Eye Field: A High-resolution fMRI Investigation
Cereb Cortex, February 1, 2002; 12(2): 107 - 115.
[Abstract] [Full Text] [PDF]

Home page
 StrokeHome page
H. Tanaka, M. Arai, J. Kubo, and K. Hirata
Conjugate Eye Deviation With Head Version due to a Cortical Infarction of the Frontal Eye Field
Stroke, February 1, 2002; 33(2): 642 - 643.
[Full Text] [PDF]

Home page
 BrainHome page
D. Gagnon, G. A. O'Driscoll, M. Petrides, and G. B. Pike
The effect of spatial and temporal information on saccades and neural activity in oculomotor structures
Brain, January 1, 2002; 125(1): 123 - 139.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Missal and S. J. Heinen
Facilitation of Smooth Pursuit Initiation by Electrical Stimulation in the Supplementary Eye Fields
J Neurophysiol, November 1, 2001; 86(5): 2413 - 2425.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. P. Dukelow, J. F. X. DeSouza, J. C. Culham, A. V. van den Berg, R. S. Menon, and T. Vilis
Distinguishing Subregions of the Human MT+ Complex Using Visual Fields and Pursuit Eye Movements
J Neurophysiol, October 1, 2001; 86(4): 1991 - 2000.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online