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The Journal of Neurophysiology Vol. 82 No. 3 September 1999, pp. 1326-1338
Copyright ©1999 by the American Physiological Society
Department of Neurobiology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272-0095
Portfors, Christine V. and
Jeffrey J. Wenstrup.
Delay-Tuned Neurons in the Inferior Colliculus of the Mustached
Bat: Implications for Analyses of Target Distance. J. Neurophysiol. 82: 1326-1338, 1999. We examined response properties of delay-tuned neurons in the
central nucleus of the inferior colliculus (ICC) of the mustached bat.
In the mustached bat, delay-tuned neurons respond best to the
combination of the first-harmonic, frequency-modulated (FM1) sweep in
the emitted pulse and a higher harmonic frequency-modulated (FM2, FM3
or FM4) component in returning echoes and are referred to as FM-FM
neurons. We also examined H1-CF2 neurons. H1-CF2 neurons responded to
simultaneous presentation of the first harmonic (H1) in the emitted
pulse and the second constant frequency (CF2) component in returning
echoes. These neurons served as a comparison as they are thought to
encode different features of sonar targets than FM-FM neurons. Only 7%
of our neurons (14/198) displayed a single excitatory tuning curve. The
rest of the neurons (184) displayed complex responses to sounds in two
separate frequency bands. The majority (51%, 101) of neurons were
facilitated by the combination of specific components in the mustached
bat's vocalizations. Twenty-five percent showed purely inhibitory
interactions. The remaining neurons responded to two separate
frequencies, without any facilitation or inhibition. FM-FM neurons (69)
were facilitated by the FM1 component in the simulated pulse and a
higher harmonic FM component in simulated echoes, provided the
high-frequency signal was delayed the appropriate amount. The delay
producing maximal facilitation ("best delay") among FM-FM neurons
ranged between 0 and 20 ms, corresponding to target distances 
3.4 m.
Sharpness of delay tuning varied among FM-FM neurons with 50% delay
widths between 2 and 13 ms. On average, the facilitated responses of
FM-FM neurons were 104% greater than the sum of the responses to the
two signals alone. In comparing response properties of delay-tuned,
FM-FM neurons in the ICC with those in the medial geniculate body (MGB) from other studies, we find that the range of best delays, sharpness of
delay tuning and strength of facilitation are similar in the ICC and
MGB. This suggests that by the level of the IC, the basic response
properties of FM-FM neurons are established, and they do not undergo
extensive transformations with ascending auditory processing.
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