JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 83: 2468-2470, 2000;
0022-3077/00 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (27)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cazalets, J.-R.
Right arrow Articles by Hilaire, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cazalets, J.-R.
Right arrow Articles by Hilaire, G.

The Journal of Neurophysiology Vol. 83 No. 4 April 2000, pp. 2468-2470
Copyright ©2000 by the American Physiological Society

RAPID COMMUNICATION

Locomotor Network Maturation Is Transiently Delayed in the MAOA-Deficient Mouse

Jean-René Cazalets, Marie Gardette, and Gérard Hilaire

Centre National de la Recherche Scientifique, Laboratoire de Neurobiologie et Mouvements, 13402 Marseille Cedex 9, France

Cazalets, Jean-René, Marie Gardette, and Gérard Hilaire. Locomotor Network Maturation Is Transiently Delayed in the MAOA-Deficient Mouse. J. Neurophysiol. 83: 2468-2470, 2000. In vivo and in vitro experiments were performed in control (C3H) and monoamine oxidase A (MAOA)-deficient (Tg8) neonatal mice to determine whether MAOA deficiency affected spinal locomotor network maturation. Comparing the swimming behaviors at birth in C3H mice with those in Tg8 mice revealed a delayed role for the hindlimbs in Tg8 swimming, even though adult swimming behavior was acquired at postnatal day 14 (P14) in both strains. Analyzing the locomotor network activity in vitro showed that serotonin (5-HT) induced and modulated locomotor-like discharges in hindlimb ventral roots of C3H but not Tg8 neonates. The Tg8 network began, however, to be affected by 5-HT at P11. Thus both in vivo and in vitro results argue for a transient delay of locomotor network maturation in the Tg8 strain.




This article has been cited by other articles:


Home page
 Lab AnimHome page
M Adencreutz and J Hau
Gender and cognitive aspects of neonatal and juvenile neuromuscular locomotor development of F1 hybrid mice in swim tests
Lab Anim, January 1, 2008; 42(1): 26 - 33.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. Wallen-Mackenzie, H. Gezelius, M. Thoby-Brisson, A. Nygard, A. Enjin, F. Fujiyama, G. Fortin, and K. Kullander
Vesicular Glutamate Transporter 2 Is Required for Central Respiratory Rhythm Generation But Not for Locomotor Central Pattern Generation.
J. Neurosci., November 22, 2006; 26(47): 12294 - 12307.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Madriaga, L. C. McPhee, T. Chersa, K. J. Christie, and P. J. Whelan
Modulation of Locomotor Activity by Multiple 5-HT and Dopaminergic Receptor Subtypes in the Neonatal Mouse Spinal Cord
J Neurophysiol, September 1, 2004; 92(3): 1566 - 1576.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
J.-F. Pflieger, F. Clarac, and L. Vinay
Postural Modifications and Neuronal Excitability Changes Induced by a Short-Term Serotonin Depletion during Neonatal Development in the Rat
J. Neurosci., June 15, 2002; 22(12): 5108 - 5117.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. Whelan, A. Bonnot, and M. J. O'Donovan
Properties of Rhythmic Activity Generated by the Isolated Spinal Cord of the Neonatal Mouse
J Neurophysiol, December 1, 2000; 84(6): 2821 - 2833.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online