| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 83 No. 6 June 2000, pp. 3351-3365
Copyright ©2000 by the American Physiological Society
1Rehabilitation Research and Development Center (153), Veterans Affairs Palo Alto Health Care System, Palo Alto 94304-1200; and 2Mechanical Engineering Department (Biomechanical Engineering Division) and 3Department of Functional Restoration, Stanford University, Stanford, California 94305-3030
Ting, Lena H.,
Steven A. Kautz,
David A. Brown, and
Felix E. Zajac.
Contralateral Movement and Extensor Force Generation Alter
Flexion Phase Muscle Coordination in Pedaling. J. Neurophysiol. 83: 3351-3365, 2000. The importance of
bilateral sensorimotor signals in coordination of locomotion has been
demonstrated in animals but is difficult to ascertain in humans due to
confounding effects of mechanical transmission of forces between the
legs (i.e., mechanical interleg coupling). In a previous pedaling
study, by eliminating mechanical interleg coupling, we showed that
muscle coordination of a unipedal task can be shaped by interlimb
sensorimotor pathways. Interlimb neural pathways were shown to alter
pedaling coordination as subjects pedaling unilaterally exhibited
increased flexion-phase muscle activity compared with
bilateral pedaling even though the task mechanics performed by the
pedaling leg(s) in the unilateral and bilateral pedaling tasks were
identical. To further examine the relationship between contralateral
sensorimotor state and ipsilateral flexion-phase muscle coordination
during pedaling, subjects in this study pedaled with one leg while the
contralateral leg either generated an extensor force or relaxed as a
servomotor either held that leg stationary or moved it in antiphase
with the pedaling leg. In the presence of contralateral extensor force
generation, muscle activity in the pedaling leg during limb flexion was
reduced. Integrated electromyographic activity of the
pedaling-leg hamstring muscles (biceps femoris and semimembranosus)
during flexion decreased by 25-30%, regardless of either the
amplitude of force generated by the nonpedaling leg or whether the leg
was stationary or moving. In contrast, rectus femoris and tibialis
anterior activity during flexion decreased only when the contralateral
leg generated high rhythmic force concomitant with leg movement. The
results are consistent with a contralateral feedforward mechanism
triggering flexion-phase hamstrings activity and a contralateral
feedback mechanism modulating rectus femoris and tibialis anterior
activity during flexion. Because only muscles that contribute to
flexion as a secondary function were observed, it is impossible to know whether the modulatory effect also acts on primary, unifunctional, limb
flexors or is specific to multifunctional muscles contributing to
flexion. The influence of contralateral extensor-phase sensorimotor signals on ipsilateral flexion may reflect bilateral coupling of gain
control mechanisms. More generally, these interlimb neural mechanisms
may coordinate activity between muscles that perform antagonistic
functions on opposite sides of the body. Because pedaling and walking
share biomechanical and neuronal control features, these mechanisms may
be operational in walking as well as pedaling.
This article has been cited by other articles:
|
|
 |
|
  S. N. Zill, B. R. Keller, and E. R. Duke Sensory Signals of Unloading in One Leg Follow Stance Onset in Another Leg: Transfer of Load and Emergent Coordination in Cockroach Walking J Neurophysiol, May 1, 2009; 101(5): 2297 - 2304. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. P. Zehr, J. E. Balter, D. P. Ferris, S. R. Hundza, P. M. Loadman, and R. H. Stoloff Neural regulation of rhythmic arm and leg movement is conserved across human locomotor tasks J. Physiol., July 1, 2007; 582(1): 209 - 227. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Torres-Oviedo, J. M. Macpherson, and L. H. Ting Muscle Synergy Organization Is Robust Across a Variety of Postural Perturbations J Neurophysiol, September 1, 2006; 96(3): 1530 - 1546. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Ridderikhoff, C. E. Peper, and P. J. Beek Unraveling Interlimb Interactions Underlying Bimanual Coordination J Neurophysiol, November 1, 2005; 94(5): 3112 - 3125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. S. Reisman, H. J. Block, and A. J. Bastian Interlimb Coordination During Locomotion: What Can be Adapted and Stored? J Neurophysiol, October 1, 2005; 94(4): 2403 - 2415. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Kautz, P. W. Duncan, S. Perera, R. R. Neptune, and S. A. Studenski Coordination of Hemiparetic Locomotion after Stroke Rehabilitation Neurorehabil Neural Repair, September 1, 2005; 19(3): 250 - 258. [Abstract] [PDF]
|
|
|
|
 |
|
 V. C. K. Cheung, A. d'Avella, M. C. Tresch, and E. Bizzi Central and Sensory Contributions to the Activation and Organization of Muscle Synergies during Natural Motor Behaviors J. Neurosci., July 6, 2005; 25(27): 6419 - 6434. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Courtine, R. R. Roy, J. Hodgson, H. McKay, J. Raven, H. Zhong, H. Yang, M. H. Tuszynski, and V. R. Edgerton Kinematic and EMG Determinants in Quadrupedal Locomotion of a Non-Human Primate (Rhesus) J Neurophysiol, June 1, 2005; 93(6): 3127 - 3145. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Kautz and C. Patten Interlimb Influences on Paretic Leg Function in Poststroke Hemiparesis J Neurophysiol, May 1, 2005; 93(5): 2460 - 2473. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Kawashima, D. Nozaki, M. O. Abe, M. Akai, and K. Nakazawa Alternate Leg Movement Amplifies Locomotor-Like Muscle Activity in Spinal Cord Injured Persons J Neurophysiol, February 1, 2005; 93(2): 777 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. H. Ting and J. M. Macpherson A Limited Set of Muscle Synergies for Force Control During a Postural Task J Neurophysiol, January 1, 2005; 93(1): 609 - 613. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Schindler-Ivens, D. A. Brown, and J. D. Brooke Direction-Dependent Phasing of Locomotor Muscle Activity Is Altered Post-Stroke J Neurophysiol, October 1, 2004; 92(4): 2207 - 2216. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. J. Huang and D. P. Ferris Neural coupling between upper and lower limbs during recumbent stepping J Appl Physiol, October 1, 2004; 97(4): 1299 - 1308. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. P. Zehr and J. Duysens Regulation of Arm and Leg Movement during Human Locomotion Neuroscientist, August 1, 2004; 10(4): 347 - 361. [Abstract] [PDF]
|
|
|
|
|
|
V. Dietz and S. J. Harkema Locomotor activity in spinal cord-injured persons J Appl Physiol, May 1, 2004; 96(5): 1954 - 1960. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Dietz, R. Muller, and G. Colombo Locomotor activity in spinal man: significance of afferent input from joint and load receptors Brain, December 1, 2002; 125(12): 2626 - 2634. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Kautz, D. A. Brown, H.F.M. Van der Loos, and F. E. Zajac Mutability of Bifunctional Thigh Muscle Activity in Pedaling due to Contralateral Leg Force Generation J Neurophysiol, September 1, 2002; 88(3): 1308 - 1317. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
