JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 84: 1120-1122, 2000;
0022-3077/00 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via ISI Web of Science (7)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shirokawa, T.
Right arrow Articles by Isobe, K.-I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shirokawa, T.
Right arrow Articles by Isobe, K.-I.

The Journal of Neurophysiology Vol. 84 No. 2 August 2000, pp. 1120-1122
Copyright ©2000 by the American Physiological Society

RAPID COMMUNICATION

Age-Dependent Changes in Axonal Branching of Single Locus Coeruleus Neurons Projecting to Two Different Terminal Fields

Tetsuya Shirokawa, Yoshiyuki Ishida, and Ken-Ichi Isobe

Laboratory of Physiology, Department of Basic Gerontology, National Institute for Longevity Sciences, Obu 474-8522, Japan

Shirokawa, Tetsuya, Yoshiyuki Ishida, and Ken-Ichi Isobe. Age-Dependent Changes in Axonal Branching of Single Locus Coeruleus Neurons Projecting to Two Different Terminal Fields. J. Neurophysiol. 84: 1120-1122, 2000. Age-dependent changes in the axonal branching patterns of single locus coeruleus neurons, which innervate both the frontal cortex and hippocampus dentate gyrus, have been studied in male F344 rats. We used an electrophysiological approach involving antidromic activation to differentiate single from multi-threshold locus coeruleus neurons in each terminal field with age (7-27 mo of age). Most of these neurons have a single threshold in the young rats, whereas in the older brains, the neurons have multi-threshold responses. This implies an increased amount of axonal branching in the older brains. The time course of the increase differs in the two terminal fields, suggesting that the degree of plasticity or age-dependent increase in branching can differ across terminal fields.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online