| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 85 No. 2 February 2001, pp. 886-899
Copyright ©2001 by the American Physiological Society
1Department of Neurology and 2Department of Neuroradiology, Klinikum Grosshadern, Ludwig-Maximilians University, 81377 Munich, Germany
Bense, Sandra,
Thomas Stephan,
Tarek A. Yousry,
Thomas Brandt, and
Marianne Dieterich.
Multisensory Cortical Signal Increases and Decreases During
Vestibular Galvanic Stimulation (fMRI). J. Neurophysiol. 85: 886-899, 2001. Functional magnetic resonance
imaging blood-oxygenation-level-dependent (BOLD) signal increases
(activations) and BOLD signal decreases ("deactivations") were
compared in six healthy volunteers during galvanic vestibular (mastoid)
and galvanic cutaneous (neck) stimulation in order to differentiate
vestibular from ocular motor and nociceptive functions. By calculating
the contrast for vestibular activation minus cutaneous activation for
the group, we found activations in the anterior parts of the insula,
the paramedian and dorsolateral thalamus, the putamen, the inferior
parietal lobule [Brodmann area (BA) 40], the precentral gyrus
(frontal eye field, BA 6), the middle frontal gyrus (prefrontal cortex, BA 46/9), the middle temporal gyrus (BA 37), the superior temporal gyrus (BA 22), and the anterior cingulate gyrus (BA 32) as well as in
both cerebellar hemispheres. These activations can be attributed to
multisensory vestibular and ocular motor functions. Single-subject analysis in addition showed distinctly nonoverlapping activations in
the posterior insula, which corresponds to the parieto-insular vestibular cortex in the monkey. During vestibular stimulation, there
was also a significant signal decrease in the visual cortex (BA 18, 19), which spared BA 17. A different "deactivation" was found
during cutaneous stimulation; it included upper parieto-occipital areas
in the middle temporal and occipital gyri (BA 19/39/18). Under both
stimulation conditions, there were signal decreases in the
somatosensory cortex (BA 2/3/4). Stimulus-dependent, inhibitory vestibular-visual, and nociceptive-somatosensory interactions may be
functionally significant for processing perception and sensorimotor control.
This article has been cited by other articles:
|
|
 |
|
  M. Dieterich and T. Brandt Functional brain imaging of peripheral and central vestibular disorders Brain, May 30, 2008; (2008) awn042v1. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. L. Miller, V. Maffei, G. Bosco, M. Iosa, M. Zago, E. Macaluso, and F. Lacquaniti Vestibular Nuclei and Cerebellum Put Visual Gravitational Motion in Context J Neurophysiol, April 1, 2008; 99(4): 1969 - 1982. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Dieterich, T. Bauermann, C. Best, P. Stoeter, and P. Schlindwein Evidence for cortical visual substitution of chronic bilateral vestibular failure (an fMRI study) Brain, August 1, 2007; 130(8): 2108 - 2116. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-O. Karnath and M. Dieterich Spatial neglect--a vestibular disorder? Brain, February 1, 2006; 129(2): 293 - 305. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Dieterich, P. Bartenstein, S. Spiegel, S. Bense, M. Schwaiger, and T. Brandt Thalamic infarctions cause side-specific suppression of vestibular cortex activations Brain, September 1, 2005; 128(9): 2052 - 2067. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Indovina, V. Maffei, G. Bosco, M. Zago, E. Macaluso, and F. Lacquaniti Representation of Visual Gravitational Motion in the Human Vestibular Cortex Science, April 15, 2005; 308(5720): 416 - 419. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. DIETERICH, S. BENSE, T. STEPHAN, T. BRANDT, M. SCHWAIGER, and P. BARTENSTEIN Medial Vestibular Nucleus Lesions in Wallenberg's Syndrome Cause Decreased Activity of the Contralateral Vestibular Cortex Ann. N.Y. Acad. Sci., April 1, 2005; 1039(1): 368 - 383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Bense, A. Deutschlander, Th. Stephan, P. Bartenstein, M. Schwaiger, Th. Brandt, and M. Dieterich Preserved visual-vestibular interaction in patients with bilateral vestibular failure Neurology, July 13, 2004; 63(1): 122 - 128. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. BENSE, T. STEPHAN, P. BARTENSTEIN, M. SCHWAIGER, T. BRANDT, and M. DIETERICH Acute Vestibular Nucleus Lesion Affects Cortical Activation Pattern during Caloric Irrigation in PET Ann. N.Y. Acad. Sci., October 1, 2003; 1004(1): 434 - 439. [Full Text] [PDF]
|
|
|
|
|
|
S. BENSE, P. BARTENSTEIN, S. LUTZ, T. STEPHAN, M. SCHWAIGER, T. BRANDT, and M. DIETERICH Three Determinants of Vestibular Hemispheric Dominance during Caloric Stimulation: A Positron Emission Tomography Study Ann. N.Y. Acad. Sci., October 1, 2003; 1004(1): 440 - 445. [Full Text] [PDF]
|
|
|
|
|
|
K. JAHN, A. DEUTSCHLANDER, T. STEPHAN, H. BRUCKMANN, M. STRUPP, and T. BRANDT Vestibular and Somatosensory Cortex Deactivation during Imagined Locomotion: A Functional Magnetic Resonance Imaging Study Ann. N.Y. Acad. Sci., October 1, 2003; 1004(1): 469 - 472. [Full Text] [PDF]
|
|
|
|
 |
|
 M. Dieterich, S. Bense, S. Lutz, A. Drzezga, T. Stephan, P. Bartenstein, and T. Brandt Dominance for Vestibular Cortical Function in the Non-dominant Hemisphere Cereb Cortex, September 1, 2003; 13(9): 994 - 1007. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Naito, I. Tateya, S. Hirano, M. Inoue, K. Funabiki, H. Toyoda, M. Ueno, K. Ishizu, Y. Nagahama, H. Fukuyama, et al. Cortical correlates of vestibulo-ocular reflex modulation: a PET study Brain, July 1, 2003; 126(7): 1562 - 1578. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Mailis-Gagnon, I. Giannoylis, J. Downar, C. L. Kwan, D. J. Mikulis, A. P. Crawley, K. Nicholson, and K. D. Davis Altered central somatosensory processing in chronic pain patients with "hysterical" anesthesia Neurology, May 13, 2003; 60(9): 1501 - 1507. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Emri, M. Kisely, Z. Lengyel, L. Balkay, T. Marian, L. Miko, E. Berenyi, I. Sziklai, L. Tron, and A. Toth Cortical Projection of Peripheral Vestibular Signaling J Neurophysiol, May 1, 2003; 89(5): 2639 - 2646. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Petit and M. S. Beauchamp Neural Basis of Visually Guided Head Movements Studied With fMRI J Neurophysiol, May 1, 2003; 89(5): 2516 - 2527. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Bove, G. Courtine, and M. Schieppati Neck Muscle Vibration and Spatial Orientation During Stepping in Place in Humans J Neurophysiol, November 1, 2002; 88(5): 2232 - 2241. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. BRANDT, S. GLASAUER, T. STEPHAN, S. BENSE, T. A. YOUSRY, A. DEUTSCHLANDER, and M. DIETERICH Visual-Vestibular and Visuovisual Cortical Interaction: New Insights from fMRI and PET Ann. N.Y. Acad. Sci., April 1, 2002; 956(1): 230 - 241. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. T. Wallace and B. E. Stein Sensory and Multisensory Responses in the Newborn Monkey Superior Colliculus J. Neurosci., November 15, 2001; 21(22): 8886 - 8894. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
