| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 85 No. 4 April 2001, pp. 1648-1660
Copyright ©2001 by the American Physiological Society
Jenks Vestibular Physiology Laboratory, Massachusetts Eye and Ear Infirmary, Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02114
Merfeld, D. M.,
L. H. Zupan, and
C. A. Gifford.
Neural Processing of Gravito-Inertial Cues in Humans. II.
Influence of the Semicircular Canals During Eccentric Rotation. J. Neurophysiol. 85: 1648-1660, 2001. All linear
accelerometers, including the otolith organs, respond equivalently to
gravity and linear acceleration. To investigate how the nervous system
resolves this ambiguity, we measured perceived roll tilt and reflexive
eye movements in humans in the dark using two different centrifugation
motion paradigms (fixed radius and variable radius) combined with two
different subject orientations (facing-motion and back-to-motion). In
the fixed radius trials, the radius at which the subject was seated was
held constant while the rotation speed was changed to yield changes in
the centrifugal force. In variable radius trials, the rotation speed
was held constant while the radius was varied to yield a centrifugal
force that nearly duplicated that measured during the fixed radius
condition. The total gravito-inertial force (GIF) measured by the
otolith organs was nearly identical in the two paradigms; the primary difference was the presence (fixed radius) or absence (variable radius)
of yaw rotational cues. We found that the yaw rotational cues had a
large statistically significant effect on the time course of perceived
tilt, demonstrating that yaw rotational cues contribute substantially
to the neural processing of roll tilt. We also found that the
orientation of the subject relative to the centripetal acceleration had
a dramatic influence on the eye movements measured during fixed radius
centrifugation. Specifically, the horizontal vestibuloocular reflex
(VOR) measured in our human subjects was always greater when the
subject faced the direction of motion than when the subjects had their
backs toward the motion during fixed radius rotation. This difference
was consistent with the presence of a horizontal translational VOR
response induced by the centripetal acceleration. Most importantly, by
comparing the perceptual tilt responses to the eye movement responses,
we found that the translational VOR component decayed as the subjective tilt indication aligned with the tilt of the GIF. This was true for
both the fixed radius and variable radius conditions even though the
time course of the responses was significantly different for these two
conditions. These findings are consistent with the hypothesis that the
nervous system resolves the ambiguous measurements of GIF into neural
estimates of gravity and linear acceleration. More generally, these
findings are consistent with the hypothesis that the nervous system
uses internal models to process and interpret sensory motor cues.
This article has been cited by other articles:
|
|
 |
|
  E. N. Lorincz and B. J. M. Hess Dynamic Effects on the Subjective Visual Vertical After Roll Rotation J Neurophysiol, August 1, 2008; 100(2): 657 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. F. Lewis, C. Haburcakova, and D. M. Merfeld Roll Tilt Psychophysics in Rhesus Monkeys During Vestibular and Visual Stimulation J Neurophysiol, July 1, 2008; 100(1): 140 - 153. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.A.A. Vingerhoets, W. P. Medendorp, and J.A.M. Van Gisbergen Body-Tilt and Visual Verticality Perception During Multiple Cycles of Roll Rotation J Neurophysiol, May 1, 2008; 99(5): 2264 - 2280. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Seemungal, S. Glasauer, M. A. Gresty, and A. M. Bronstein Vestibular Perception and Navigation in the Congenitally Blind J Neurophysiol, June 1, 2007; 97(6): 4341 - 4356. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.A.A. Vingerhoets, J.A.M. Van Gisbergen, and W. P. Medendorp Verticality Perception During Off-Vertical Axis Rotation J Neurophysiol, May 1, 2007; 97(5): 3256 - 3268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. A. Yong, G. D. Paige, and S. H. Seidman Multiple Sensory Cues Underlying the Perception of Translation and Path J Neurophysiol, February 1, 2007; 97(2): 1100 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Zhou, B. F. Tang, S. D. Newlands, and W. M. King Responses of Monkey Vestibular-Only Neurons to Translation and Angular Rotation J Neurophysiol, December 1, 2006; 96(6): 2915 - 2930. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Park, C. Gianna-Poulin, F. O. Black, S. Wood, and D. M. Merfeld Roll Rotation Cues Influence Roll Tilt Perception Assayed Using a Somatosensory Technique J Neurophysiol, July 1, 2006; 96(1): 486 - 491. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R.A.A. Vingerhoets, W. P. Medendorp, and J.A.M. Van Gisbergen Time Course and Magnitude of Illusory Translation Perception During Off-Vertical Axis Rotation J Neurophysiol, March 1, 2006; 95(3): 1571 - 1587. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Merfeld, S. Park, C. Gianna-Poulin, F. O. Black, and S. Wood Vestibular Perception and Action Employ Qualitatively Different Mechanisms. I. Frequency Response of VOR and Perceptual Responses During Translation and Tilt J Neurophysiol, July 1, 2005; 94(1): 186 - 198. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Merfeld, S. Park, C. Gianna-Poulin, F. O. Black, and S. Wood Vestibular Perception and Action Employ Qualitatively Different Mechanisms. II. VOR and Perceptual Responses During Combined Tilt&Translation J Neurophysiol, July 1, 2005; 94(1): 199 - 205. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. J. M. Hess, K. Jaggi-Schwarz, and H. Misslisch Canal-Otolith Interactions After Off-Vertical Axis Rotations. II. Spatiotemporal Properties of Roll and Pitch Postrotatory Vestibuloocular Reflexes J Neurophysiol, March 1, 2005; 93(3): 1633 - 1646. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Peterka, C. C. Gianna-Poulin, L. H. Zupan, and D. M. Merfeld Origin of Orientation-Dependent Asymmetries in Vestibulo-Ocular Reflexes Evoked by Caloric Stimulation J Neurophysiol, October 1, 2004; 92(4): 2333 - 2345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Angelaki Eyes on Target: What Neurons Must do for the Vestibuloocular Reflex During Linear Motion J Neurophysiol, July 1, 2004; 92(1): 20 - 35. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Pavlou, N. Wijnberg, M. E. Faldon, and A. M. Bronstein Effect of Semicircular Canal Stimulation on the Perception of the Visual Vertical J Neurophysiol, August 1, 2003; 90(2): 622 - 630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. H. Zupan and D. M. Merfeld Neural Processing of Gravito-Inertial Cues in Humans. IV. Influence of Visual Rotational Cues During Roll Optokinetic Stimuli J Neurophysiol, January 1, 2003; 89(1): 390 - 400. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Schneider, S. Glasauer, and M. Dieterich Comparison of Human Ocular Torsion Patterns During Natural and Galvanic Vestibular Stimulation J Neurophysiol, April 1, 2002; 87(4): 2064 - 2073. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Merfeld and L. H. Zupan Neural Processing of Gravitoinertial Cues in Humans. III. Modeling Tilt and Translation Responses J Neurophysiol, February 1, 2002; 87(2): 819 - 833. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
