JN Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


J Neurophysiol 85: 1969-1985, 2001;
0022-3077/01 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (276)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Steriade, M.
Right arrow Articles by Grenier, F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Steriade, M.
Right arrow Articles by Grenier, F.

The Journal of Neurophysiology Vol. 85 No. 5 May 2001, pp. 1969-1985
Copyright ©2001 by the American Physiological Society

Natural Waking and Sleep States: A View From Inside Neocortical Neurons

M. Steriade, I. Timofeev, and F. Grenier

Laboratoire de Neurophysiologie, Faculté de Médicine, Université Laval, Quebec G1K 7P4, Canada

Steriade, M., I. Timofeev, and F. Grenier. Natural Waking and Sleep States: A View From Inside Neocortical Neurons. J. Neurophysiol. 85: 1969-1985, 2001. In this first intracellular study of neocortical activities during waking and sleep states, we hypothesized that synaptic activities during natural states of vigilance have a decisive impact on the observed electrophysiological properties of neurons that were previously studied under anesthesia or in brain slices. We investigated the incidence of different firing patterns in neocortical neurons of awake cats, the relation between membrane potential fluctuations and firing rates, and the input resistance during all states of vigilance. In awake animals, the neurons displaying fast-spiking firing patterns were more numerous, whereas the incidence of neurons with intrinsically bursting patterns was much lower than in our previous experiments conducted on the intact-cortex or isolated cortical slabs of anesthetized cats. Although cortical neurons displayed prolonged hyperpolarizing phases during slow-wave sleep, the firing rates during the depolarizing phases of the slow sleep oscillation was as high during these epochs as during waking and rapid-eye-movement sleep. Maximum firing rates, exceeding those of regular-spiking neurons, were reached by conventional fast-spiking neurons during both waking and sleep states, and by fast-rhythmic-bursting neurons during waking. The input resistance was more stable and it increased during quiet wakefulness, compared with sleep states. As waking is associated with high synaptic activity, we explain this result by a higher release of activating neuromodulators, which produce an increase in the input resistance of cortical neurons. In view of the high firing rates in the functionally disconnected state of slow-wave sleep, we suggest that neocortical neurons are engaged in processing internally generated signals.




This article has been cited by other articles:


Home page
J. Neurophysiol.Home page
S. K. Esser, S. Hill, and G. Tononi
Breakdown of Effective Connectivity During Slow Wave Sleep: Investigating the Mechanism Underlying a Cortical Gate Using Large-Scale Modeling
J Neurophysiol, October 1, 2009; 102(4): 2096 - 2111.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C. Curto, S. Sakata, S. Marguet, V. Itskov, and K. D. Harris
A Simple Model of Cortical Dynamics Explains Variability and State Dependence of Sensory Responses in Urethane-Anesthetized Auditory Cortex
J. Neurosci., August 26, 2009; 29(34): 10600 - 10612.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
H. Ros, R. N. S. Sachdev, Y. Yu, N. Sestan, and D. A. McCormick
Neocortical Networks Entrain Neuronal Circuits in Cerebellar Cortex
J. Neurosci., August 19, 2009; 29(33): 10309 - 10320.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
P. Rigas and M. A. Castro-Alamancos
Impact of Persistent Cortical Activity (Up States) on Intracortical and Thalamocortical Synaptic Inputs
J Neurophysiol, July 1, 2009; 102(1): 119 - 131.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
C.-y. T. Li, M.-m. Poo, and Y. Dan
Burst Spiking of a Single Cortical Neuron Modifies Global Brain State
Science, May 1, 2009; 324(5927): 643 - 646.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
V. V. Vyazovskiy, U. Faraguna, C. Cirelli, and G. Tononi
Triggering Slow Waves During NREM Sleep in the Rat by Intracortical Electrical Stimulation: Effects of Sleep/Wake History and Background Activity
J Neurophysiol, April 1, 2009; 101(4): 1921 - 1931.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
O. Valenti and A. A. Grace
Entorhinal Cortex Inhibits Medial Prefrontal Cortex and Modulates the Activity States of Electrophysiologically Characterized Pyramidal Neurons In Vivo
Cereb Cortex, March 1, 2009; 19(3): 658 - 674.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
F. R. Fernandez and J. A. White
Reduction of Spike Afterdepolarization by Increased Leak Conductance Alters Interspike Interval Variability
J. Neurosci., January 28, 2009; 29(4): 973 - 986.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. B. Dash, C. L. Douglas, V. V. Vyazovskiy, C. Cirelli, and G. Tononi
Long-Term Homeostasis of Extracellular Glutamate in the Rat Cerebral Cortex across Sleep and Waking States
J. Neurosci., January 21, 2009; 29(3): 620 - 629.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
F. N. Karameh and S. G. Massaquoi
Intracortical Augmenting Responses in Networks of Reduced Compartmental Models of Tufted Layer 5 Cells
J Neurophysiol, January 1, 2009; 101(1): 207 - 233.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
P. E. Pomata, M. A. Belluscio, L. A. Riquelme, and M. G. Murer
NMDA Receptor Gating of Information Flow through the Striatum In Vivo
J. Neurosci., December 10, 2008; 28(50): 13384 - 13389.
[Abstract] [Full Text] [PDF]


Home page
Biol. Bull.Home page
G. Tononi
Consciousness as Integrated Information: a Provisional Manifesto
Biol. Bull., December 1, 2008; 215(3): 216 - 242.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
M. T. Alkire, A. G. Hudetz, and G. Tononi
Consciousness and Anesthesia
Science, November 7, 2008; 322(5903): 876 - 880.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
D. Balduzzi, B. A. Riedner, and G. Tononi
A BOLD window into brain waves
PNAS, October 14, 2008; 105(41): 15641 - 15642.
[Full Text] [PDF]


Home page
J. Neurophysiol.Home page
N. V. Povysheva, A. V. Zaitsev, D. C. Rotaru, G. Gonzalez-Burgos, D. A. Lewis, and L. S. Krimer
Parvalbumin-Positive Basket Interneurons in Monkey and Rat Prefrontal Cortex
J Neurophysiol, October 1, 2008; 100(4): 2348 - 2360.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
T. T. Dang-Vu, M. Schabus, M. Desseilles, G. Albouy, M. Boly, A. Darsaud, S. Gais, G. Rauchs, V. Sterpenich, G. Vandewalle, et al.
Spontaneous neural activity during human slow wave sleep
PNAS, September 30, 2008; 105(39): 15160 - 15165.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
S. Avramescu and I. Timofeev
Synaptic Strength Modulation after Cortical Trauma: A Role in Epileptogenesis
J. Neurosci., July 2, 2008; 28(27): 6760 - 6772.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
F. Kasanetz, L. A. Riquelme, V. Della-Maggiore, P. O'Donnell, and M. G. Murer
Functional integration across a gradient of corticostriatal channels controls UP state transitions in the dorsal striatum
PNAS, June 10, 2008; 105(23): 8124 - 8129.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
D. Vierling-Claassen, P. Siekmeier, S. Stufflebeam, and N. Kopell
Modeling GABA Alterations in Schizophrenia: A Link Between Impaired Inhibition and Altered Gamma and Beta Range Auditory Entrainment
J Neurophysiol, May 1, 2008; 99(5): 2656 - 2671.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
U. Faraguna, V. V. Vyazovskiy, A. B. Nelson, G. Tononi, and C. Cirelli
A Causal Role for Brain-Derived Neurotrophic Factor in the Homeostatic Regulation of Sleep
J. Neurosci., April 9, 2008; 28(15): 4088 - 4095.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
V. V. Vyazovskiy and I. Tobler
Handedness Leads to Interhemispheric EEG Asymmetry During Sleep in the Rat
J Neurophysiol, February 1, 2008; 99(2): 969 - 975.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
S. R. Williams and S. E. Atkinson
Pathway-specific use-dependent dynamics of excitatory synaptic transmission in rat intracortical circuits
J. Physiol., December 15, 2007; 585(3): 759 - 777.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
A. M. Hattox and S. B. Nelson
Layer V Neurons in Mouse Cortex Projecting to Different Targets Have Distinct Physiological Properties
J Neurophysiol, December 1, 2007; 98(6): 3330 - 3340.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
D. Kroeger and F. Amzica
Hypersensitivity of the Anesthesia-Induced Comatose Brain
J. Neurosci., September 26, 2007; 27(39): 10597 - 10607.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. Hasenstaub, R. N. S. Sachdev, and D. A. McCormick
State Changes Rapidly Modulate Cortical Neuronal Responsiveness
J. Neurosci., September 5, 2007; 27(36): 9607 - 9622.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
F. Bengtsson and H. Jorntell
Ketamine and Xylazine Depress Sensory-Evoked Parallel Fiber and Climbing Fiber Responses
J Neurophysiol, September 1, 2007; 98(3): 1697 - 1705.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
M. Bertini, M. Ferrara, L. De Gennaro, G. Curcio, F. Moroni, F. Vecchio, M. De Gasperis, P. M. Rossini, and C. Babiloni
Directional Information Flows between Brain Hemispheres during Presleep Wake and Early Sleep Stages
Cereb Cortex, August 1, 2007; 17(8): 1970 - 1978.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
D. L. Ringach and B. J. Malone
The Operating Point of the Cortex: Neurons as Large Deviation Detectors
J. Neurosci., July 18, 2007; 27(29): 7673 - 7683.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
H. Okamoto, Y. Isomura, M. Takada, and T. Fukai
Temporal Integration by Stochastic Recurrent Network Dynamics With Bimodal Neurons
J Neurophysiol, June 1, 2007; 97(6): 3859 - 3867.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
B. Haider, A. Duque, A. R. Hasenstaub, Y. Yu, and D. A. McCormick
Enhancement of Visual Responsiveness by Spontaneous Local Network Activity In Vivo
J Neurophysiol, June 1, 2007; 97(6): 4186 - 4202.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
D. Sussillo, T. Toyoizumi, and W. Maass
Self-Tuning of Neural Circuits Through Short-Term Synaptic Plasticity
J Neurophysiol, June 1, 2007; 97(6): 4079 - 4095.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Rudolph, M. Pospischil, I. Timofeev, and A. Destexhe
Inhibition Determines Membrane Potential Dynamics and Controls Action Potential Generation in Awake and Sleeping Cat Cortex
J. Neurosci., May 16, 2007; 27(20): 5280 - 5290.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
M. Massimini, F. Ferrarelli, S. K. Esser, B. A. Riedner, R. Huber, M. Murphy, M. J. Peterson, and G. Tononi
Triggering sleep slow waves by transcranial magnetic stimulation
PNAS, May 15, 2007; 104(20): 8496 - 8501.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
D. B. Carr and D. J. Surmeier
M1 Muscarinic Receptor Modulation of Kir2 Channels Enhances Temporal Summation of Excitatory Synaptic Potentials in Prefrontal Cortex Pyramidal Neurons
J Neurophysiol, May 1, 2007; 97(5): 3432 - 3438.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
P. Rigas and M. A. Castro-Alamancos
Thalamocortical Up States: Differential Effects of Intrinsic and Extrinsic Cortical Inputs on Persistent Activity
J. Neurosci., April 18, 2007; 27(16): 4261 - 4272.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
A. Kepecs and S. Raghavachari
Gating Information by Two-State Membrane Potential Fluctuations
J Neurophysiol, April 1, 2007; 97(4): 3015 - 3023.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
D. Durstewitz and T. Gabriel
Dynamical Basis of Irregular Spiking in NMDA-Driven Prefrontal Cortex Neurons
Cereb Cortex, April 1, 2007; 17(4): 894 - 908.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
T. T. G. Hahn, B. Sakmann, and M. R. Mehta
Differential responses of hippocampal subfields to cortical up-down states
PNAS, March 20, 2007; 104(12): 5169 - 5174.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
F. S. Chance
Receiver Operating Characteristic (ROC) Analysis for Characterizing Synaptic Efficacy
J Neurophysiol, February 1, 2007; 97(2): 1799 - 1808.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
D. A. Nita, Y. Cisse, I. Timofeev, and M. Steriade
Waking-Sleep Modulation of Paroxysmal Activities Induced by Partial Cortical Deafferentation
Cereb Cortex, February 1, 2007; 17(2): 272 - 283.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
M. Mukovski, S. Chauvette, I. Timofeev, and M. Volgushev
Detection of Active and Silent States in Neocortical Neurons from the Field Potential Signal during Slow-Wave Sleep
Cereb Cortex, February 1, 2007; 17(2): 400 - 414.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
A. Czarnecki, B. Birtoli, and D. Ulrich
Cellular mechanisms of burst firing-mediated long-term depression in rat neocortical pyramidal cells
J. Physiol., January 15, 2007; 578(2): 471 - 479.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
A. Luczak, P. Bartho, S. L. Marguet, G. Buzsaki, and K. D. Harris
Sequential structure of neocortical spontaneous activity in vivo
PNAS, January 2, 2007; 104(1): 347 - 352.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
Y. Shu, A. Duque, Y. Yu, B. Haider, and D. A. McCormick
Properties of Action-Potential Initiation in Neocortical Pyramidal Cells: Evidence From Whole Cell Axon Recordings
J Neurophysiol, January 1, 2007; 97(1): 746 - 760.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. D. Humphries, R. D. Stewart, and K. N. Gurney
A Physiologically Plausible Model of Action Selection and Oscillatory Activity in the Basal Ganglia
J. Neurosci., December 13, 2006; 26(50): 12921 - 12942.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
S. Mahon, N. Vautrelle, L. Pezard, S. J. Slaght, J.-M. Deniau, G. Chouvet, and S. Charpier
Distinct Patterns of Striatal Medium Spiny Neuron Activity during the Natural Sleep-Wake Cycle
J. Neurosci., November 29, 2006; 26(48): 12587 - 12595.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. R. DeWeese and A. M. Zador
Non-Gaussian Membrane Potential Dynamics Imply Sparse, Synchronous Activity in Auditory Cortex.
J. Neurosci., November 22, 2006; 26(47): 12206 - 12218.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
W. van Drongelen, H. Koch, F. P. Elsen, H. C. Lee, A. Mrejeru, E. Doren, C. J. Marcuccilli, M. Hereld, R. L. Stevens, and J.-M. Ramirez
Role of Persistent Sodium Current in Bursting Activity of Mouse Neocortical Networks In Vitro
J Neurophysiol, November 1, 2006; 96(5): 2564 - 2577.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
A. Destexhe and D. Contreras
Neuronal computations with stochastic network states.
Science, October 6, 2006; 314(5796): 85 - 90.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
R. Haslinger, I. Ulbert, C. I. Moore, E. N. Brown, and A. Devor
Analysis of LFP Phase Predicts Sensory Response of Barrel Cortex
J Neurophysiol, September 1, 2006; 96(3): 1658 - 1663.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
J. Waters and F. Helmchen
Background synaptic activity is sparse in neocortex.
J. Neurosci., August 9, 2006; 26(32): 8267 - 8277.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
F. Frohlich, M. Bazhenov, I. Timofeev, M. Steriade, and T. J. Sejnowski
Slow state transitions of sustained neural oscillations by activity-dependent modulation of intrinsic excitability.
J. Neurosci., June 7, 2006; 26(23): 6153 - 6162.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
T. Wolansky, E. A. Clement, S. R. Peters, M. A. Palczak, and C. T. Dickson
Hippocampal slow oscillation: a novel EEG state and its coordination with ongoing neocortical activity.
J. Neurosci., June 7, 2006; 26(23): 6213 - 6229.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Volgushev, S. Chauvette, M. Mukovski, and I. Timofeev
Precise Long-Range Synchronization of Activity and Silence in Neocortical Neurons during Slow-Wave Sleep
J. Neurosci., May 24, 2006; 26(21): 5665 - 5672.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
S. Crochet, P. Fuentealba, Y. Cisse, I. Timofeev, and M. Steriade
Synaptic Plasticity in Local Cortical Network In Vivo and Its Modulation by the Level of Neuronal Activity
Cereb Cortex, May 1, 2006; 16(5): 618 - 631.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
S. Fujisawa, N. Matsuki, and Y. Ikegaya
Single Neurons Can Induce Phase Transitions of Cortical Recurrent Networks with Multiple Internal States
Cereb Cortex, May 1, 2006; 16(5): 639 - 654.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
B. Haider, A. Duque, A. R. Hasenstaub, and D. A. McCormick
Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition.
J. Neurosci., April 26, 2006; 26(17): 4535 - 4545.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
R. B. Levy, A. D. Reyes, and C. Aoki
Nicotinic and Muscarinic Reduction of Unitary Excitatory Postsynaptic Potentials in Sensory Cortex; Dual Intracellular Recording In Vitro
J Neurophysiol, April 1, 2006; 95(4): 2155 - 2166.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
K. L. Blethyn, S. W. Hughes, T. I. Toth, D. W. Cope, and V. Crunelli
Neuronal Basis of the Slow (<1 Hz) Oscillation in Neurons of the Nucleus Reticularis Thalami In Vitro
J. Neurosci., March 1, 2006; 26(9): 2474 - 2486.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
D. Guan, J. C. F. Lee, T. Tkatch, D. J. Surmeier, W. E. Armstrong, and R. C. Foehring
Expression and biophysical properties of Kv1 channels in supragranular neocortical pyramidal neurones
J. Physiol., March 1, 2006; 571(2): 371 - 389.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
N. S. Desai and E. C. Walcott
Synaptic bombardment modulates muscarinic effects in forelimb motor cortex.
J. Neurosci., February 22, 2006; 26(8): 2215 - 2226.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
D. A. Nita, Y. Cisse, I. Timofeev, and M. Steriade
Increased Propensity to Seizures After Chronic Cortical Deafferentation In Vivo
J Neurophysiol, February 1, 2006; 95(2): 902 - 913.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
E. Christophe, N. Doerflinger, D. J. Lavery, Z. Molnar, S. Charpak, and E. Audinat
Two Populations of Layer V Pyramidal Cells of the Mouse Neocortex: Development and Sensitivity to Anesthetics
J Neurophysiol, November 1, 2005; 94(5): 3357 - 3367.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Rosanova and D. Ulrich
Pattern-Specific Associative Long-Term Potentiation Induced by a Sleep Spindle-Related Spike Train
J. Neurosci., October 12, 2005; 25(41): 9398 - 9405.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
M. Rudolph, J. G. Pelletier, D. Pare, and A. Destexhe
Characterization of Synaptic Conductances and Integrative Properties During Electrically Induced EEG-Activated States in Neocortical Neurons In Vivo
J Neurophysiol, October 1, 2005; 94(4): 2805 - 2821.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
M. Massimini, F. Ferrarelli, R. Huber, S. K. Esser, H. Singh, and G. Tononi
Breakdown of Cortical Effective Connectivity During Sleep
Science, September 30, 2005; 309(5744): 2228 - 2232.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
S. R. Williams
Encoding and Decoding of Dendritic Excitation during Active States in Pyramidal Neurons
J. Neurosci., June 22, 2005; 25(25): 5894 - 5902.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
V. Zsiros and S. Hestrin
Background Synaptic Conductance and Precision of EPSP-Spike Coupling at Pyramidal Cells
J Neurophysiol, June 1, 2005; 93(6): 3248 - 3256.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
A. Fontanini and J. M. Bower
Variable Coupling Between Olfactory System Activity and Respiration in Ketamine/Xylazine Anesthetized Rats
J Neurophysiol, June 1, 2005; 93(6): 3573 - 3581.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
A. R. Houweling, M. Bazhenov, I. Timofeev, M. Steriade, and T. J. Sejnowski
Homeostatic Synaptic Plasticity Can Explain Post-traumatic Epileptogenesis in Chronically Isolated Neocortex
Cereb Cortex, June 1, 2005; 15(6): 834 - 845.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C. Cirelli, R. Huber, A. Gopalakrishnan, T. L. Southard, and G. Tononi
Locus Ceruleus Control of Slow-Wave Homeostasis
J. Neurosci., May 4, 2005; 25(18): 4503 - 4511.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
S. Hill and G. Tononi
Modeling Sleep and Wakefulness in the Thalamocortical System
J Neurophysiol, March 1, 2005; 93(3): 1671 - 1698.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
M. Rosanova and I. Timofeev
Neuronal mechanisms mediating the variability of somatosensory evoked potentials during sleep oscillations in cats
J. Physiol., January 15, 2005; 562(2): 569 - 582.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
K. Y. Tseng and P. O'Donnell
Post-pubertal Emergence of Prefrontal Cortical Up States Induced by D1-NMDA Co-activation
Cereb Cortex, January 1, 2005; 15(1): 49 - 57.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
J. Waters and F. Helmchen
Boosting of Action Potential Backpropagation by Neocortical Network Activity In Vivo
J. Neurosci., December 8, 2004; 24(49): 11127 - 11136.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
D. Gervasoni, S.-C. Lin, S. Ribeiro, E. S. Soares, J. Pantoja, and M. A. L. Nicolelis
Global Forebrain Dynamics Predict Rat Behavioral States and Their Transitions
J. Neurosci., December 8, 2004; 24(49): 11137 - 11147.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
L. Marshall, M. Molle, M. Hallschmid, and J. Born
Transcranial Direct Current Stimulation during Sleep Improves Declarative Memory
J. Neurosci., November 3, 2004; 24(44): 9985 - 9992.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
S. Crochet, P. Fuentealba, I. Timofeev, and M. Steriade
Selective Amplification of Neocortical Neuronal Output by Fast Prepotentials InVivo
Cereb Cortex, October 1, 2004; 14(10): 1110 - 1121.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
M. E. Larkum, W. Senn, and H.-R. Luscher
Top-down Dendritic Input Increases the Gain of Layer 5 Pyramidal Neurons
Cereb Cortex, October 1, 2004; 14(10): 1059 - 1070.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Massimini, R. Huber, F. Ferrarelli, S. Hill, and G. Tononi
The Sleep Slow Oscillation as a Traveling Wave
J. Neurosci., August 4, 2004; 24(31): 6862 - 6870.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
I. Timofeev, F. Grenier, and M. Steriade
Contribution of Intrinsic Neuronal Factors in the Generation of Cortically Driven Electrographic Seizures
J Neurophysiol, August 1, 2004; 92(2): 1133 - 1143.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
E. M. Izhikevich, J. A. Gally, and G. M. Edelman
Spike-timing Dynamics of Neuronal Groups
Cereb Cortex, August 1, 2004; 14(8): 933 - 944.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
I. A. Erchova and M. E. Diamond
Rapid Fluctuations in Rat Barrel Cortex Plasticity
J. Neurosci., June 30, 2004; 24(26): 5931 - 5941.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
P. Fuentealba, I. Timofeev, and M. Steriade
From The Cover: Prolonged hyperpolarizing potentials precede spindle oscillations in the thalamic reticular nucleus
PNAS, June 29, 2004; 101(26): 9816 - 9821.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
C. Cirelli and G. Tononi
Locus Ceruleus Control of State-Dependent Gene Expression
J. Neurosci., June 9, 2004; 24(23): 5410 - 5419.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
B. Birtoli and D. Ulrich
Firing Mode-Dependent Synaptic Plasticity in Rat Neocortical Pyramidal Neurons
J. Neurosci., May 26, 2004; 24(21): 4935 - 4940.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
M. O. Cunningham, M. A. Whittington, A. Bibbig, A. Roopun, F. E. N. LeBeau, A. Vogt, H. Monyer, E. H. Buhl, and R. D. Traub
A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro
PNAS, May 4, 2004; 101(18): 7152 - 7157.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
P. Fuentealba, S. Crochet, I. Timofeev, and M. Steriade
Synaptic Interactions Between Thalamic and Cortical Inputs Onto Cortical Neurons In Vivo
J Neurophysiol, May 1, 2004; 91(5): 1990 - 1998.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
A. Massaux, G. Dutrieux, N. Cotillon-Williams, Y. Manunta, and J.-M. Edeline
Auditory Thalamus Bursts in Anesthetized and Non-Anesthetized States: Contribution to Functional Properties
J Neurophysiol, May 1, 2004; 91(5): 2117 - 2134.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
T. Kobayashi, C. Good, J. Biedermann, C. Barnes, R. D. Skinner, and E. Garcia-Rill
Developmental Changes in Pedunculopontine Nucleus (PPN) Neurons
J Neurophysiol, April 1, 2004; 91(4): 1470 - 1481.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
Y. Shu, A. Hasenstaub, M. Badoual, T. Bal, and D. A. McCormick
Barrages of Synaptic Activity Control the Gain and Sensitivity of Cortical Neurons
J. Neurosci., November 12, 2003; 23(32): 10388 - 10401.
[Abstract] [Full Text] [PDF]


Home page
Cereb CortexHome page
D. A. McCormick, Y. Shu, A. Hasenstaub, M. Sanchez-Vives, M. Badoual, and T. Bal
Persistent Cortical Activity: Mechanisms of Generation and Effects on Neuronal Excitability
Cereb Cortex, November 1, 2003; 13(11): 1219 - 1231.
[Abstract] [Full Text] [PDF]


Home page
J. Neurophysiol.Home page
T. Berger, W. Senn, and H.-R. Luscher
Hyperpolarization-Activated Current Ih Disconnects Somatic and Dendritic Spike Initiation Zones in Layer V Pyramidal Neurons
J Neurophysiol, October 1, 2003; 90(4): 2428 - 2437.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
A. DESTEXHE and T. J. SEJNOWSKI
Interactions Between Membrane Conductances Underlying Thalamocortical Slow-Wave Oscillations
Physiol Rev, October 1, 2003; 83(4): 1401 - 1453.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
J. He
Slow Oscillation in Non-Lemniscal Auditory Thalamus
J. Neurosci., September 10, 2003; 23(23): 8281 - 8290.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. Fontanini, P. Spano, and J. M. Bower
Ketamine-Xylazine-Induced Slow (< 1.5 Hz) Oscillations in the Rat Piriform (Olfactory) Cortex Are Functionally Correlated with Respiration
J. Neurosci., September 3, 2003; 23(22): 7993 - 8001.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online