JN Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 86: 1062-1066, 2001;
0022-3077/01 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (51)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gaese, B. H.
Right arrow Articles by Ostwald, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gaese, B. H.
Right arrow Articles by Ostwald, J.

The Journal of Neurophysiology Vol. 86 No. 2 August 2001, pp. 1062-1066
Copyright ©2001 by the American Physiological Society

RAPID COMMUNICATION

Anesthesia Changes Frequency Tuning of Neurons in the Rat Primary Auditory Cortex

Bernhard H. Gaese and Joachim Ostwald

Department of Animal Physiology, University of Tübingen, D-72076 Tubingen, Germany

Gaese, Bernhard H. and Joachim Ostwald. Anesthesia Changes Frequency Tuning of Neurons in the Rat Primary Auditory Cortex. J. Neurophysiol. 86: 1062-1066, 2001. The vast majority of investigations on central auditory processing so far were conducted under the influence of an anesthetic agent. It remains unclear, however, to what extend even basic response properties of central auditory neurons are influenced by this experimental manipulation. We used a combination of chronic recording in unrestrained animals, computer-controlled randomized acoustic stimulation, and statistical evaluation of responses to directly compare the response characteristics of single neurons in the awake and anesthetized state. Thereby we were able to quantify the effects of pentobarbital/chloral hydrate anesthesia (Equithesin) on rat auditory cortical neurons. During Equithesin anesthesia, only a portion of central neurons were active and some of their basic response properties were changed. Only 29% of the neurons still had a frequency response area. Their tuning sharpness was increased under anesthesia. Most changes are consistent with an enhancement of inhibitory influences during Equithesin anesthesia. Thus when describing response properties of central auditory neurons, the animal's anesthetic state has to be taken into account.




This article has been cited by other articles:


Home page
 J. Neurosci.Home page
W. von der Behrens, P. Bauerle, M. Kossl, and B. H. Gaese
Correlating Stimulus-Specific Adaptation of Cortical Neurons and Local Field Potentials in the Awake Rat
J. Neurosci., November 4, 2009; 29(44): 13837 - 13849.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. Fontanini and D. B. Katz
Behavioral States, Network States, and Sensory Response Variability
J Neurophysiol, September 1, 2008; 100(3): 1160 - 1168.
[Abstract] [Full Text] [PDF]

Home page
 Phil Trans R Soc BHome page
E. D Young
Neural representation of spectral and temporal information in speech
Phil Trans R Soc B, March 12, 2008; 363(1493): 923 - 945.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
P. K. Pandya, D. L. Rathbun, R. Moucha, N. D. Engineer, and M. P. Kilgard
Spectral and Temporal Processing in Rat Posterior Auditory Cortex
Cereb Cortex, February 1, 2008; 18(2): 301 - 314.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. C. Puckett, P. K. Pandya, R. Moucha, W. Dai, and M. P. Kilgard
Plasticity in the Rat Posterior Auditory Field Following Nucleus Basalis Stimulation
J Neurophysiol, July 1, 2007; 98(1): 253 - 265.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. H. Scott, B. J. Malone, and M. N. Semple
Effect of Behavioral Context on Representation of a Spatial Cue in Core Auditory Cortex of Awake Macaques
J. Neurosci., June 13, 2007; 27(24): 6489 - 6499.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Ter-Mikaelian, D. H. Sanes, and M. N. Semple
Transformation of Temporal Properties between Auditory Midbrain and Cortex in the Awake Mongolian Gerbil
J. Neurosci., June 6, 2007; 27(23): 6091 - 6102.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
H. H. Lim and D. J. Anderson
Auditory Cortical Responses to Electrical Stimulation of the Inferior Colliculus: Implications for an Auditory Midbrain Implant
J Neurophysiol, September 1, 2006; 96(3): 975 - 988.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. Moshitch, L. Las, N. Ulanovsky, O. Bar-Yosef, and I. Nelken
Responses of Neurons in Primary Auditory Cortex (A1) to Pure Tones in the Halothane-Anesthetized Cat
J Neurophysiol, June 1, 2006; 95(6): 3756 - 3769.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. Engelmann, J. Bacelo, E. van den Burg, and K. Grant
Sensory and Motor Effects of Etomidate Anesthesia
J Neurophysiol, February 1, 2006; 95(2): 1231 - 1243.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. L. Bartlett and X. Wang
Long-Lasting Modulation by Stimulus Context in Primate Auditory Cortex
J Neurophysiol, July 1, 2005; 94(1): 83 - 104.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. E. Cohen, B. E. Russ, G. W. Gifford III, R. Kiringoda, and K. A. MacLean
Selectivity for the Spatial and Nonspatial Attributes of Auditory Stimuli in the Ventrolateral Prefrontal Cortex
J. Neurosci., December 15, 2004; 24(50): 11307 - 11316.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. H. Bonham, S. W. Cheung, B. Godey, and C. E. Schreiner
Spatial Organization of Frequency Response Areas and Rate/Level Functions in the Developing AI
J Neurophysiol, February 1, 2004; 91(2): 841 - 854.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. Zhang, K. T. Nakamoto, and L. M. Kitzes
Binaural Interaction Revisited in the Cat Primary Auditory Cortex
J Neurophysiol, January 1, 2004; 91(1): 101 - 117.
[Abstract] [Full Text]

Home page
 J. Neurophysiol.Home page
D. Suta, E. Kvasnak, J. Popelar, and J. Syka
Representation of Species-Specific Vocalizations in the Inferior Colliculus of the Guinea Pig
J Neurophysiol, December 1, 2003; 90(6): 3794 - 3808.
[Abstract] [Full Text] [PDF]

Home page
 Br J AnaesthHome page
B. Antkowiak
In vitro networks: cortical mechanisms of anaesthetic action
Br. J. Anaesth., July 1, 2002; 89(1): 102 - 111.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. Liang, T. Lu, and X. Wang
Neural Representations of Sinusoidal Amplitude and Frequency Modulations in the Primary Auditory Cortex of Awake Primates
J Neurophysiol, May 1, 2002; 87(5): 2237 - 2261.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. S. Nagarajan, S. W. Cheung, P. Bedenbaugh, R. E. Beitel, C. E. Schreiner, and M. M. Merzenich
Representation of Spectral and Temporal Envelope of Twitter Vocalizations in Common Marmoset Primary Auditory Cortex
J Neurophysiol, April 1, 2002; 87(4): 1723 - 1737.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. B. Katz, S. A. Simon, and M. A. L. Nicolelis
Taste-Specific Neuronal Ensembles in the Gustatory Cortex of Awake Rats
J. Neurosci., March 1, 2002; 22(5): 1850 - 1857.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online