| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
The Journal of Neurophysiology Vol. 86 No. 2 August 2001, pp. 935-949
Copyright ©2001 by the American Physiological Society
1Neurology Department, Zürich University Hospital, CH-8091 Zürich; 2Institute of Theoretical Physics, Eidgenössisch-Technische Hochschule, CH-8093 Zürich, Switzerland; and 3Department of Ophthalmology, Sapporo Medical University, 060-8543 Sapporo, Japan
Scherberger, Hansjörg,
Jan-Harry Cabungcal,
Klaus Hepp,
Yasuo Suzuki,
Dominik Straumann, and
Volker Henn.
Ocular Counterroll Modulates the Preferred Direction of
Saccade-Related Pontine Burst Neurons in the Monkey. J. Neurophysiol. 86: 935-949, 2001. Saccade-related burst
neurons in the paramedian pontine reticular formation (PPRF) of the
head-restrained monkey provide a phasic velocity signal to extraocular
motoneurons for the generation of rapid eye movements. In the superior
colliculus (SC), which directly projects to the PPRF, the motor command
for conjugate saccades with the head restrained in a roll position is
represented in a reference frame in between oculocentric and
space-fixed coordinates with a clear bias toward gravity. Here we
studied the preferred direction of premotor burst neurons in the PPRF
during static head roll to characterize their frame of reference with
respect to head and eye position. In 59 neurons (short-lead,
burst-tonic, and long-lead burst neurons), we found that the preferred
direction of eye displacement of these neurons changed, relative to
head-fixed landmarks, in the horizontal-vertical plane during static
head roll. For the short-lead burst neurons and the burst-tonic group, the change was about one-fourth of the amount of ocular counterroll (OCR) and significantly different from a head-centered representation. In the long-lead burst neurons, the rotation of the preferred direction
showed a larger trend of about one-half of OCR. During microelectrical
stimulation of the PPRF (9 sites in 2 monkeys), the elicited eye
movements rotated with about one-half the amount of OCR. In a simple
pulley model of the oculomotor plant, the noncraniocentric reference
frame of the PPRF output neurons could be reproduced for recently
measured pulley positions, if the pulleys were assumed to rotate as a
function of OCR with a gain of 0.5. We conclude that the saccadic
displacement signal is transformed from a representation in the SC with
a clear bias to gravity to a representation in the PPRF that is closely
craniocentric, but rotates with OCR, consistent with current concepts
of the oculomotor plant.
This article has been cited by other articles:
|
|
 |
|
  F. F. Ghasia, H. Meng, and D. E. Angelaki Neural Correlates of Forward and Inverse Models for Eye Movements: Evidence from Three-Dimensional Kinematics J. Neurosci., May 7, 2008; 28(19): 5082 - 5087. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Ren, A. Z. Khan, G. Blohm, D.Y.P. Henriques, L. E. Sergio, and J. D. Crawford Proprioceptive Guidance of Saccades in Eye-Hand Coordination J Neurophysiol, September 1, 2006; 96(3): 1464 - 1477. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Demer and R. A. Clark Magnetic Resonance Imaging of Human Extraocular Muscles During Static Ocular Counter-Rolling J Neurophysiol, November 1, 2005; 94(5): 3292 - 3302. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Demer Pivotal Role of Orbital Connective Tissues in Binocular Alignment and Strabismus The Friedenwald Lecture Invest. Ophthalmol. Vis. Sci., March 1, 2004; 45(3): 729 - 738. [Full Text] [PDF]
|
|
|
|
|
|
J. L. Demer, S. Y. Oh, R. A. Clark, and V. Poukens Evidence for a Pulley of the Inferior Oblique Muscle Invest. Ophthalmol. Vis. Sci., September 1, 2003; 44(9): 3856 - 3865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. J.M. Hess and D. E. Angelaki Gravity Modulates Listing's Plane Orientation During Both Pursuit and Saccades J Neurophysiol, August 1, 2003; 90(2): 1340 - 1345. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Demer, R. Kono, and W. Wright Magnetic Resonance Imaging of Human Extraocular Muscles in Convergence J Neurophysiol, April 1, 2003; 89(4): 2072 - 2085. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. E. Angelaki and J. D. Dickman Premotor Neurons Encode Torsional Eye Velocity during Smooth-Pursuit Eye Movements J. Neurosci., April 1, 2003; 23(7): 2971 - 2979. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Kono, R. A. Clark, and J. L. Demer Active Pulleys: Magnetic Resonance Imaging of Rectus Muscle Paths in Tertiary Gazes Invest. Ophthalmol. Vis. Sci., July 1, 2002; 43(7): 2179 - 2188. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. DEMER The Orbital Pulley System: A Revolution in Concepts of Orbital Anatomy Ann. N.Y. Acad. Sci., April 1, 2002; 956(1): 17 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. HASLWANTER Mechanics of Eye Movements: Implications of the "Orbital Revolution" Ann. N.Y. Acad. Sci., April 1, 2002; 956(1): 33 - 41. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
