JN Miami Valley Hospital
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 87: 1007-1017, 2002;
0022-3077/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (34)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zheng, T.
Right arrow Articles by Wilson, C. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zheng, T.
Right arrow Articles by Wilson, C. J.

The Journal of Neurophysiology Vol. 87 No. 2 February 2002, pp. 1007-1017
Copyright ©2002 by the American Physiological Society

Corticostriatal Combinatorics: The Implications of Corticostriatal Axonal Arborizations

T. Zheng1 and C. J. Wilson2

 1Department of Neuroscience, The University of Florida, Gainesville, Florida 32611; and  2Cajal Neuroscience Research Center, University of Texas at San Antonio, San Antonio, Texas 78249

Zheng, T. and C. J. Wilson. Corticostriatal Combinatorics: The Implications of Corticostriatal Axonal Arborizations. J. Neurophysiol. 87: 1007-1017, 2002. The complete striatal axonal arborizations of 16 juxtacellularly stained cortical pyramidal cells were analyzed. Corticostriatal neurons were located in the medial agranular or anterior cingulate cortex of rats. All axons were of the extended type and formed synaptic contacts in both the striosomal and matrix compartments as determined by counterstaining for the mu-opiate receptor. Six axonal arborizations were from collaterals of brain stem-projecting cells and the other 10 from bilaterally projecting cells with no brain stem projections. The distribution of synaptic boutons along the axons were convolved with the average dendritic tree volume of spiny projection neurons to obtain an axonal innervation volume and innervation density map for each axon. Innervation volumes varied widely, with single axons occupying between 0.4 and 14.2% of the striatum (average = 4%). The total number of boutons formed by individual axons ranged from 25 to 2,900 (average = 879). Within the innervation volume, the density of innervation was extremely sparse but inhomogeneous. The pattern of innervation resembled matrisomes, as defined by bulk labeling and functional mapping experiments, superimposed on a low background innervation. Using this sample as representative of all corticostriatal axons, the total number of corticostriatal neurons was estimated to be 17 million, about 10 times the number of striatal projection neurons.




This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
F. Kasanetz, L. A. Riquelme, V. Della-Maggiore, P. O'Donnell, and M. G. Murer
Functional integration across a gradient of corticostriatal channels controls UP state transitions in the dorsal striatum
PNAS, June 10, 2008; 105(23): 8124 - 8129.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. M. Logan, J. G. Partridge, J. A. Matta, A. Buonanno, and S. Vicini
Long-Lasting NMDA Receptor-Mediated EPSCs in Mouse Striatal Medium Spiny Neurons
J Neurophysiol, November 1, 2007; 98(5): 2693 - 2704.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. G. Carter, G. J. Soler-Llavina, and B. L. Sabatini
Timing and Location of Synaptic Inputs Determine Modes of Subthreshold Integration in Striatal Medium Spiny Neurons
J. Neurosci., August 15, 2007; 27(33): 8967 - 8977.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. N. Haber, K.-S. Kim, P. Mailly, and R. Calzavara
Reward-Related Cortical Inputs Define a Large Striatal Region in Primates That Interface with Associative Cortical Connections, Providing a Substrate for Incentive-Based Learning.
J. Neurosci., August 9, 2006; 26(32): 8368 - 8376.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
O. Hikosaka, K. Nakamura, and H. Nakahara
Basal Ganglia Orient Eyes to Reward
J Neurophysiol, February 1, 2006; 95(2): 567 - 584.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. Koos, J. M. Tepper, and C. J. Wilson
Comparison of IPSCs Evoked by Spiny and Fast-Spiking Neurons in the Neostriatum
J. Neurosci., September 8, 2004; 24(36): 7916 - 7922.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. J. Magill, A. Sharott, M. D. Bevan, P. Brown, and J. P. Bolam
Synchronous Unit Activity and Local Field Potentials Evoked in the Subthalamic Nucleus by Cortical Stimulation
J Neurophysiol, August 1, 2004; 92(2): 700 - 714.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. J. Slaght, T. Paz, M. Chavez, J.-M. Deniau, S. Mahon, and S. Charpier
On the Activity of the Corticostriatal Networks during Spike-and-Wave Discharges in a Genetic Model of Absence Epilepsy
J. Neurosci., July 28, 2004; 24(30): 6816 - 6825.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. T. Blackwell, U. Czubayko, and D. Plenz
Quantitative Estimate of Synaptic Inputs to Striatal Neurons during Up and Down States In Vitro
J. Neurosci., October 8, 2003; 23(27): 9123 - 9132.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Ramanathan, J. J. Hanley, J.-M. Deniau, and J. P. Bolam
Synaptic Convergence of Motor and Somatosensory Cortical Afferents onto GABAergic Interneurons in the Rat Striatum
J. Neurosci., September 15, 2002; 22(18): 8158 - 8169.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online