JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 87: 1244-1251, 2002;
0022-3077/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (14)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Buss, R. R.
Right arrow Articles by Drapeau, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Buss, R. R.
Right arrow Articles by Drapeau, P.

The Journal of Neurophysiology Vol. 87 No. 3 March 2002, pp. 1244-1251
Copyright ©2002 by the American Physiological Society

Activation of Embryonic Red and White Muscle Fibers During Fictive Swimming in the Developing Zebrafish

Robert R. Buss and Pierre Drapeau

Centre for Research in Neuroscience, Montreal General Hospital Research Institute; and Department of Neurology and Neurosurgery and Department of Biology, McGill University, Montreal, Quebec H3G 1A4, Canada

Buss, Robert R. and Pierre Drapeau. Activation of Embryonic Red and White Muscle Fibers During Fictive Swimming in the Developing Zebrafish. J. Neurophysiol. 87: 1244-1251, 2002. Sub-threshold, motoneuron-evoked synaptic activity was observed in zebrafish embryonic red (ER) and white (EW) muscle fibers paralyzed with a dose of D-tubocurarine insufficient to abolish synaptic activity to determine whether muscle activation was coordinated to produce the undulating body movements required for locomotion. Paired whole-cell recordings revealed a synaptic drive that alternated between ipsilateral and contralateral myotomes and exhibited a rostral-caudal delay in timing appropriate for swimming. Both ER and EW muscle were activated during fictive swimming. However, at the fastest fictive swimming rates, ER fibers were de-recruited, whereas they could be active in isolation of EW fibers at the slowest fictive swimming rates. Prior to hatching, fictive swimming was preceded by a lower frequency, more robust and rhythmic synaptic drive resembling the "coiling" behavior of fish embryos. The motor activity observed in paralyzed zebrafish closely resembled the swimming and coiling behaviors observed in these developing fishes. At the early developmental stages examined in this study, myotomal muscle recruitment and coordination were similar to that observed in adult fishes during swimming. Our results indicate that the patterned activation of myotomal muscle is set from the onset of development.




This article has been cited by other articles:


Home page
 J. Gen. Physiol.Home page
V. M. Luna and P. Brehm
An Electrically Coupled Network of Skeletal Muscle in Zebrafish Distributes Synaptic Current
J. Gen. Physiol., June 26, 2006; 128(1): 89 - 102.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. R. McDearmid and P. Drapeau
Rhythmic Motor Activity Evoked by NMDA in the Spinal Zebrafish Larva
J Neurophysiol, January 1, 2006; 95(1): 401 - 417.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
T. van der Meulen, H. Schipper, J. L. van Leeuwen, and S. Kranenbarg
Effects of decreased muscle activity on developing axial musculature in nicb107 mutant zebrafish (Danio rerio)
J. Exp. Biol., October 1, 2005; 208(19): 3675 - 3687.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
S. D. Buckingham and D. W. Ali
Computer simulations of high-pass filtering in zebrafish larval muscle fibres
J. Exp. Biol., August 15, 2005; 208(16): 3055 - 3063.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Hirata, L. Saint-Amant, G. B. Downes, W. W. Cui, W. Zhou, M. Granato, and J. Y. Kuwada
Zebrafish bandoneon mutants display behavioral defects due to a mutation in the glycine receptor {beta}-subunit
PNAS, June 7, 2005; 102(23): 8345 - 8350.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
W. W. Cui, L. Saint-Amant, and J. Y. Kuwada
shocked Gene Is Required for the Function of a Premotor Network in the Zebrafish CNS
J Neurophysiol, November 1, 2004; 92(5): 2898 - 2908.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
H. Hirata, L. Saint-Amant, J. Waterbury, W. Cui, W. Zhou, Q. Li, D. Goldman, M. Granato, and J. Y. Kuwada
accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1
Development, November 1, 2004; 131(21): 5457 - 5468.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
S. D. Buckingham and D. W. Ali
Sodium and potassium currents of larval zebrafish muscle fibres
J. Exp. Biol., February 15, 2004; 207(5): 841 - 852.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. R. Buss, C. W. Bourque, and P. Drapeau
Membrane Properties Related to the Firing Behavior of Zebrafish Motoneurons
J Neurophysiol, February 1, 2003; 89(2): 657 - 664.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol PatholHome page
J. M. Spitsbergen and M. L. Kent
The State of the Art of the Zebrafish Model for Toxicology and Toxicologic Pathology Research--Advantages and Current Limitations
Toxicol Pathol, January 1, 2003; 31(1_suppl): 62 - 87.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online