JN Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 89: 81-89, 2003. First published October 10, 2002; doi:10.1152/jn.00542.2002
0022-3077/03 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
89/1/81    most recent
00542.2002v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (28)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kubota, D.
Right arrow Articles by Lynch, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kubota, D.
Right arrow Articles by Lynch, G.

J Neurophysiol (January 1, 2003). 10.1152/jn.00542.2002
Submitted on Submitted 10 July 2002; accepted in final form 3 September 2002

Endogenous Waves in Hippocampal Slices

Don Kubota,1 Laura Lee Colgin,2 Malcolm Casale,3 Fernando A. Brucher,3 and Gary Lynch3

 1Department of Information and Computer Science,  2Institute for Mathematical Behavioral Sciences, and  3Department of Psychiatry and Human Behavior, University of California, Irvine, California 92612

Kubota, Don, Laura Lee Colgin, Malcolm Casale, Fernando A. Brucher, and Gary Lynch. Endogenous Waves in Hippocampal Slices. J. Neurophysiol. 89: 81-89, 2003. Sharp waves (SPWs) are thought to play a major role in intrinsic hippocampal operations during states in which subcortical and cortical inputs to hippocampus are reduced. This study describes evidence that such activity occurs spontaneously in appropriately prepared rat hippocampal slices. Irregular waves, with an average frequency of approximately 4 Hz, were recorded from field CA3 in slices prepared from the temporal region of hippocampus. The waves persisted for hours and were not accompanied by aberrant discharges. Multi-electrode analyses established that they were locally generated within each of the subfields of CA3 and yet were coherent between subfields. The sharp waves were reversibly blocked by either cholinergic or serotonergic stimulation. Various lines of evidence indicate that they are propagated by the CA3 associational system.




This article has been cited by other articles:


Home page
 J. Physiol.Home page
C. Le Duigou, V. Bouilleret, and R. Miles
Epileptiform activities in slices of hippocampus from mice after intra-hippocampal injection of kainic acid
J. Physiol., October 15, 2008; 586(20): 4891 - 4904.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
D. Fabo, Z. Magloczky, L. Wittner, A. Pek, L. Eross, S. Czirjak, J. Vajda, A. Solyom, G. Rasonyi, A. Szucs, et al.
Properties of in vivo interictal spike generation in the human subiculum
Brain, February 1, 2008; 131(2): 485 - 499.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
C. P. Wu, H. L. Huang, M. N. Asl, J. W. He, J. Gillis, F. K. Skinner, and L. Zhang
Spontaneous rhythmic field potentials of isolated mouse hippocampal-subicular-entorhinal cortices in vitro
J. Physiol., October 15, 2006; 576(2): 457 - 476.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. L. Brunson, E. Kramar, B. Lin, Y. Chen, L. L. Colgin, T. K. Yanagihara, G. Lynch, and T. Z. Baram
Mechanisms of Late-Onset Cognitive Decline after Early-Life Stress
J. Neurosci., October 12, 2005; 25(41): 9328 - 9338.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. Wu, M. N. Asl, J. Gillis, F. K. Skinner, and L. Zhang
An In Vitro Model of Hippocampal Sharp Waves: Regional Initiation and Intracellular Correlates
J Neurophysiol, July 1, 2005; 94(1): 741 - 753.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
C. Wu, W. P. Luk, J. Gillis, F. Skinner, and L. Zhang
Size Does Matter: Generation of Intrinsic Network Rhythms in Thick Mouse Hippocampal Slices
J Neurophysiol, April 1, 2005; 93(4): 2302 - 2317.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. L. Colgin, D. Kubota, F. A. Brucher, Y. Jia, E. Branyan, C. M. Gall, and G. Lynch
Spontaneous Waves in the Dentate Gyrus of Slices From the Ventral Hippocampus
J Neurophysiol, December 1, 2004; 92(6): 3385 - 3398.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
L. L. Colgin, D. Kubota, Y. Jia, C. S. Rex, and G. Lynch
Long-term potentiation is impaired in rat hippocampal slices that produce spontaneous sharp waves
J. Physiol., August 1, 2004; 558(3): 953 - 961.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
N. Maier, V. Nimmrich, and A. Draguhn
Cellular and Network Mechanisms Underlying Spontaneous Sharp Wave-Ripple Complexes in Mouse Hippocampal Slices
J. Physiol., August 1, 2003; 550(3): 873 - 887.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online