| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
J Neurophysiol (February 1, 2003). 10.1152/jn.00607.2002
Submitted on Submitted 26 July 2002; accepted in final form 21 October 2002
Centre de Recherche en Sciences Neurologiques, Département de Physiologie, Université de Montreal, C.P. 6128 Succursale Centre-ville, Montreal, Quebec H3C 3J7, Canada
Cisek, Paul,
Donald J. Crammond, and
John F. Kalaska.
Neural Activity in Primary Motor and Dorsal Premotor Cortex In
Reaching Tasks With the Contralateral Versus Ipsilateral Arm. J. Neurophysiol. 89: 922-942, 2003. To investigate the effector dependence of task-related neural activity
in dorsal premotor (PMd) and primary motor cortex (M1), directional
tuning functions were compared between instructed-delay reaching tasks
performed separately with either the contralateral or the ipsilateral
limb. During presentation of the instructional cue, the majority
(55/90, 61%) of cells in PMd were tuned with both arms, and their
dynamic range showed a trend for stronger discharge with the
contralateral arm. Most strikingly, however, the preferred direction of
most of these latter cells (41/55, 75%) was not significantly
different between arms. During movement, many PMd cells continued to be
tuned with both arms (53/90, 59%), with a trend for increasing
directional differences between the arms over the course of the trial.
In contrast, during presentation of the instructional cue only 5/74
(7%) cells in M1 were tuned with both arms. During movement, about
half of M1 cells (41/74, 55%) were tuned with both arms but the
preferred directions of their tuning functions were often very
different and there was a strong bias toward greater discharge rates
when the contralateral arm was used. Similar trends were observed for
EMG activity. In conclusion, M1 is strongly activated during movements
of the contralateral arm, but activity during ipsilateral arm movements
is also common and usually different from that seen with the
contralateral arm. In contrast, a major component of task-related
activity in PMd represents movement in a more abstract or
task-dependent and effector-independent manner, especially during the
instructed-delay period.
This article has been cited by other articles:
|
|
 |
|
  S. M. Beurze, F. P. de Lange, I. Toni, and W. P. Medendorp Spatial and Effector Processing in the Human Parietofrontal Network for Reaches and Saccades J Neurophysiol, June 1, 2009; 101(6): 3053 - 3062. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Brus-Ramer, J. B. Carmel, and J. H. Martin Motor Cortex Bilateral Motor Representation Depends on Subcortical and Interhemispheric Interactions J. Neurosci., May 13, 2009; 29(19): 6196 - 6206. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Chakrabarty, K. M. Friel, and J. H. Martin Activity-Dependent Plasticity Improves M1 Motor Representation and Corticospinal Tract Connectivity J Neurophysiol, March 1, 2009; 101(3): 1283 - 1293. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Duque and R. B. Ivry Role of Corticospinal Suppression during Motor Preparation Cereb Cortex, January 6, 2009; (2009) bhn230v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. W. C. Chang, A. R. Dickinson, and L. H. Snyder Limb-Specific Representation for Reaching in the Posterior Parietal Cortex J. Neurosci., June 11, 2008; 28(24): 6128 - 6140. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Bestmann, O. Swayne, F. Blankenburg, C. C. Ruff, P. Haggard, N. Weiskopf, O. Josephs, J. Driver, J. C. Rothwell, and N. S. Ward Dorsal Premotor Cortex Exerts State-Dependent Causal Influences on Activity in Contralateral Primary Motor and Dorsal Premotor Cortex Cereb Cortex, June 1, 2008; 18(6): 1281 - 1291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Perez and L. G. Cohen Mechanisms Underlying Functional Changes in the Primary Motor Cortex Ipsilateral to an Active Hand J. Neurosci., May 28, 2008; 28(22): 5631 - 5640. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-H. Song, N. Takahashi, and R. M. McPeek Target Selection for Visually Guided Reaching in Macaque J Neurophysiol, January 1, 2008; 99(1): 14 - 24. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Lebedev, J. E. O'Doherty, and M. A. L. Nicolelis Decoding of Temporal Intervals From Cortical Ensemble Activity J Neurophysiol, January 1, 2008; 99(1): 166 - 186. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kurata Laterality of Movement-Related Activity Reflects Transformation of Coordinates in Ventral Premotor Cortex and Primary Motor Cortex of Monkeys J Neurophysiol, October 1, 2007; 98(4): 2008 - 2021. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Y. Schaefer, K. Y. Haaland, and R. L. Sainburg Ipsilesional motor deficits following stroke reflect hemispheric specializations for movement control Brain, August 1, 2007; 130(8): 2146 - 2158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M Davare, J Duque, Y Vandermeeren, J-L Thonnard, and E Olivier Role of the Ipsilateral Primary Motor Cortex in Controlling the Timing of Hand Muscle Recruitment Cereb Cortex, February 1, 2007; 17(2): 353 - 362. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Beurze, F. P. de Lange, I. Toni, and W. P. Medendorp Integration of Target and Effector Information in the Human Brain During Reach Planning J Neurophysiol, January 1, 2007; 97(1): 188 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Cisek Preparing for Speed. Focus on "Preparatory Activity in Premotor and Motor Cortex Reflects the Speed of the Upcoming Reach" J Neurophysiol, December 1, 2006; 96(6): 2842 - 2843. [Full Text] [PDF]
|
|
|
|
|
|
E. Hoshi and J. Tanji Differential Involvement of Neurons in the Dorsal and Ventral Premotor Cortex During Processing of Visual Signals for Action Planning J Neurophysiol, June 1, 2006; 95(6): 3596 - 3616. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Davare, M. Andres, G. Cosnard, J.-L. Thonnard, and E. Olivier Dissociating the role of ventral and dorsal premotor cortex in precision grasping. J. Neurosci., February 22, 2006; 26(8): 2260 - 2268. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Sergio, C. Hamel-Paquet, and J. F. Kalaska Motor Cortex Neural Correlates of Output Kinematics and Kinetics During Isometric-Force and Arm-Reaching Tasks J Neurophysiol, October 1, 2005; 94(4): 2353 - 2378. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Ochiai, H. Mushiake, and J. Tanji Involvement of the Ventral Premotor Cortex in Controlling Image Motion of the Hand During Performance of a Target-capturing Task Cereb Cortex, July 1, 2005; 15(7): 929 - 937. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Perfiliev Bilateral Processing of Motor Commands in the Motor Cortex of the Cat During Target-Reaching J Neurophysiol, May 1, 2005; 93(5): 2489 - 2506. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Hoshi and J. Tanji Differential Roles of Neuronal Activity in the Supplementary and Presupplementary Motor Areas: From Information Retrieval to Motor Planning and Execution J Neurophysiol, December 1, 2004; 92(6): 3482 - 3499. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Wenderoth, F. Debaere, S. Sunaert, P. v. Hecke, and S. P. Swinnen Parieto-premotor Areas Mediate Directional Interference During Bimanual Movements Cereb Cortex, October 1, 2004; 14(10): 1153 - 1163. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Crawford, W. P. Medendorp, and J. J. Marotta Spatial Transformations for Eye-Hand Coordination J Neurophysiol, July 1, 2004; 92(1): 10 - 19. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Greger, S. A. Norris, and W. T. Thach Spike Firing in the Lateral Cerebellar Cortex Correlated With Movement and Motor Parameters Irrespective of the Effector Limb J Neurophysiol, January 1, 2004; 91(1): 576 - 582. [Abstract] [Full Text]
|
|
|
|
|
|
U. Rokni, O. Steinberg, E. Vaadia, and H. Sompolinsky Cortical Representation of Bimanual Movements J. Neurosci., December 17, 2003; 23(37): 11577 - 11586. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
