| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
J Neurophysiol (April 1, 2003). 10.1152/jn.00582.2002
Submitted on Submitted 22 July 2002; accepted in final form 11 December 2002
Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261
Temereanca, Simona and
Daniel J. Simons.
Local Field Potentials and the Encoding of Whisker Deflections by
Population Firing Synchrony in Thalamic Barreloids. J. Neurophysiol. 89: 2137-2145, 2003. In
layer IV of rat somatosensory cortex, barrel circuitry is highly
sensitive to thalamic population firing rates during the first few
milliseconds of the whisker-evoked response. This sensitivity of barrel
neurons to thalamic firing synchrony was inferred previously from
analysis of simulated barrel circuitry and from single-unit recordings
performed one at a time. In this study, we investigate stimulus-dependent synchronous activity in the thalamic ventral posteromedial nucleus (VPm) using the more direct approach of local
field potential (LFP) recording. We report that thalamic barreloid
neurons generate larger magnitude LFP responses to principal versus
adjacent whiskers, to preferred versus nonpreferred movement directions, and to high- versus low-velocity/acceleration deflections. Responses were better predicted by acceleration than velocity, and they
were insensitive to the final amplitude of whisker deflection. Importantly, reliable and robust stimulus/response relationships were
found only for the initial 1.2-7.5 ms of the thalamic LFP response,
reflecting arrival of afferent information from the brain stem. Later
components of the thalamic response, which are likely to coincide with
arrival of inhibitory inputs from the thalamic reticular nucleus and
excitatory inputs from the barrel cortex itself, are variable and
poorly predicted by stimulus parameters. Together with previous
results, these findings underscore a critical role for thalamic firing
synchrony in the encoding of small but rapidly changing perturbations
of specific whiskers in particular directions.
This article has been cited by other articles:
|
|
 |
|
  D. J. Simons, G. E. Carvell, H. T. Kyriazi, and R. M. Bruno Thalamocortical Conduction Times and Stimulus-Evoked Responses in the Rat Whisker-to-Barrel System J Neurophysiol, November 1, 2007; 98(5): 2842 - 2847. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Khatri and D. J. Simons Angularly Nonspecific Response Suppression in Rat Barrel Cortex Cereb Cortex, March 1, 2007; 17(3): 599 - 609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Haslinger, I. Ulbert, C. I. Moore, E. N. Brown, and A. Devor Analysis of LFP Phase Predicts Sensory Response of Barrel Cortex J Neurophysiol, September 1, 2006; 96(3): 1658 - 1663. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Hentschke, F. Haiss, and C. Schwarz Central Signals Rapidly Switch Tactile Processing in Rat Barrel Cortex during Whisker Movements Cereb Cortex, August 1, 2006; 16(8): 1142 - 1156. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. Bruno and B. Sakmann Cortex is driven by weak but synchronously active thalamocortical synapses. Science, June 16, 2006; 312(5780): 1622 - 1627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kida, S. Shimegi, and H. Sato Similarity of Direction Tuning Among Responses to Stimulation of Different Whiskers in Neurons of Rat Barrel Cortex J Neurophysiol, September 1, 2005; 94(3): 2004 - 2018. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. B. Wilent and D. Contreras Stimulus-Dependent Changes in Spike Threshold Enhance Feature Selectivity in Rat Barrel Cortex Neurons J. Neurosci., March 16, 2005; 25(11): 2983 - 2991. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Steinschneider, I. O. Volkov, Y. I. Fishman, H. Oya, J. C. Arezzo, and M. A. Howard III Intracortical Responses in Human and Monkey Primary Auditory Cortex Support a Temporal Processing Mechanism for Encoding of the Voice Onset Time Phonetic Parameter Cereb Cortex, February 1, 2005; 15(2): 170 - 186. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. M. Jones, D. A. Depireux, D. J. Simons, and A. Keller Robust Temporal Coding in the Trigeminal System Science, June 25, 2004; 304(5679): 1986 - 1989. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. I. Moore Frequency-Dependent Processing in the Vibrissa Sensory System J Neurophysiol, June 1, 2004; 91(6): 2390 - 2399. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. B. Wilent and D. Contreras Synaptic Responses to Whisker Deflections in Rat Barrel Cortex as a Function of Cortical Layer and Stimulus Intensity J. Neurosci., April 21, 2004; 24(16): 3985 - 3998. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-H. Lee and D. J. Simons Angular Tuning and Velocity Sensitivity in Different Neuron Classes Within Layer 4 of Rat Barrel Cortex J Neurophysiol, January 1, 2004; 91(1): 223 - 229. [Abstract] [Full Text]
|
|
|
|
|
|
E. Timofeeva, C. Merette, C. Emond, P. Lavallee, and M. Deschenes A Map of Angular Tuning Preference in Thalamic Barreloids J. Neurosci., November 19, 2003; 23(33): 10717 - 10723. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Deschenes, E. Timofeeva, and P. Lavallee The Relay of High-Frequency Sensory Signals in the Whisker-to-Barreloid Pathway J. Neurosci., July 30, 2003; 23(17): 6778 - 6787. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
