| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1Department of Health Sciences and 2Department of Physiology, Hokkaido University School of Medicine, Sapporo 060-8638, Japan; and 3Department of Physiology and Biophysics and Washington National Primate Research Center, University of Washington, Seattle, Washington 98195
Submitted 24 November 2003; accepted in final form 3 January 2004
The primate frontal cortex contains two areas related to smooth-pursuit: the frontal eye fields (FEFs) and supplementary eye fields (SEFs). To distinguish the specific role of the SEFs in pursuit, we examined discharge of a total of 89 pursuit-related neurons that showed consistent modulation when head-stabilized Japanese monkeys pursued a spot moving sinusoidally in fronto-parallel planes and/or in depth and with or without passive whole body rotation. During smooth-pursuit at different frequencies, 43% of the neurons tested (17/40) exhibited discharge amplitude of modulation linearly correlated with eye velocity. During cancellation of the vestibulo-ocular reflex and/or chair rotation in complete darkness, the majority of neurons tested (91% = 30/33) responded. However, only 17% of the responding neurons (4/30) were modulated in proportion to gaze (eye-in-space) velocity during pursuit-vestibular interactions. When the monkeys fixated a stationary spot, 20% of neurons tested (7/34) responded to motion of a second spot. Among the neurons tested for both smooth-pursuit and vergence tracking (n = 56), 27% (15/56) discharged during both, 62% (35/56) responded during smooth-pursuit only, and 11% (6/56) during vergence tracking only. Phase shifts (relative to stimulus velocity) of responding neurons during pursuit in frontal and depth planes and during chair rotation remained virtually constant (
1 Hz). These results, together with the robust vestibular-related discharge of most SEF neurons, show that the discharge of the majority of SEF pursuit-related neurons is quite distinct from that of caudal FEF neurons in identical task conditions, suggesting that the two areas are involved in different aspects of pursuit-vestibular interactions including predictive pursuit.
This article has been cited by other articles:
|
|
 |
|
  R. Ackerley, K. Wild, and A. Makin Cognitive Influences on the Generation of Eye Movements J. Neurosci., September 3, 2008; 28(36): 8863 - 8864. [Full Text] [PDF]
|
|
|
|
 |
|
 G. R. Barnes and C.J.S. Collins Evidence for a Link Between the Extra-Retinal Component of Random-Onset Pursuit and the Anticipatory Pursuit of Predictable Object Motion J Neurophysiol, August 1, 2008; 100(2): 1135 - 1146. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Nitta, T. Akao, S. Kurkin, and K. Fukushima Involvement of the Cerebellar Dorsal Vermis in Vergence Eye Movements in Monkeys Cereb Cortex, May 1, 2008; 18(5): 1042 - 1057. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. de Hemptinne, P. Lefevre, and M. Missal Neuronal Bases of Directional Expectation and Anticipatory Pursuit J. Neurosci., April 23, 2008; 28(17): 4298 - 4310. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Meng, P. J. May, J. D. Dickman, and D. E. Angelaki Vestibular Signals in Primate Thalamus: Properties and Origins J. Neurosci., December 12, 2007; 27(50): 13590 - 13602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Wei, N. Li, S. D. Newlands, J. D. Dickman, and D. E. Angelaki Deficits and Recovery in Visuospatial Memory During Head Motion After Bilateral Labyrinthine Lesion J Neurophysiol, September 1, 2006; 96(3): 1676 - 1682. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Park, M. Schlag-Rey, and J. Schlag Frames of Reference for Saccadic Command Tested By Saccade Collision in the Supplementary Eye Field J Neurophysiol, January 1, 2006; 95(1): 159 - 170. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. L. Chen and M. M. G. Walton Head Movement Evoked By Electrical Stimulation in the Supplementary Eye Field of the Rhesus Monkey J Neurophysiol, December 1, 2005; 94(6): 4502 - 4519. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Akao, M. J. Mustari, J. Fukushima, S. Kurkin, and K. Fukushima Discharge Characteristics of Pursuit Neurons in MST During Vergence Eye Movements J Neurophysiol, May 1, 2005; 93(5): 2415 - 2434. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
