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J Neurophysiol 93: 3029-3031, 2005; doi:10.1152/classicessays.00026.2005
0022-3077/05 $8.00

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EDITORIAL FOCUS

ESSAYS ON APS CLASSIC PAPERS

Synaptic chemistry in single neurons: GABA is identified as an inhibitory neurotransmitter

This essay looks at the historical significance of two APS classic papers that are freely available online:

Kravitz EA, Kuffler SW, and Potter DD. Gamma-aminobutyric acid and other blocking compounds in Crustacea. III. Their relative concentrations in separated motor and inhibitory axons. J Neurophysiol 26: 739–751, 1963 (http://jn.physiology.org/cgi/reprint/26/5/739).

Otsuka M, Kravitz EA, and Potter DD. Physiological and chemical architecture of a lobster ganglion with particular reference to gamma-aminobutyrate and glutamate. J Neurophysiol 30: 725–752, 1967 (http://jn.physiology.org/cgi/reprint/30/4/725).