HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: 97/2/1738    most recent 00189.2006v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (5) Citing Articles via Google Scholar Google Scholar Articles by Merriam, E. P. Articles by Colby, C. L. Search for Related Content PubMed PubMed Citation Articles by Merriam, E. P. Articles by Colby, C. L.

Remapping in Human Visual Cortex

¹Department of Neuroscience, University of Pittsburgh; ²Department of Statistics, Carnegie Mellon University; and ³Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania

Submitted 21 February 2006; accepted in final form 1 November 2006

With each eye movement, stationary objects in the world change position on the retina, yet we perceive the world as stable. Spatial updating, or remapping, is one neural mechanism by which the brain compensates for shifts in the retinal image caused by voluntary eye movements. Remapping of a visual representation is believed to arise from a widespread neural circuit including parietal and frontal cortex. The current experiment tests the hypothesis that extrastriate visual areas in human cortex have access to remapped spatial information. We tested this hypothesis using functional magnetic resonance imaging (fMRI). We first identified the borders of several occipital lobe visual areas using standard retinotopic techniques. We then tested subjects while they performed a single-step saccade task analogous to the task used in neurophysiological studies in monkeys, and two conditions that control for visual and motor effects. We analyzed the fMRI time series data with a nonlinear, fully Bayesian hierarchical statistical model. We identified remapping as activity in the single-step task that could not be attributed to purely visual or oculomotor effects. The strength of remapping was roughly monotonic with position in the visual hierarchy: remapped responses were largest in areas V3A and hV4 and smallest in V1 and V2. These results demonstrate that updated visual representations are present in cortical areas that are directly linked to visual perception.

This article has been cited by other articles:

				S. L. Prime, M. Vesia, and J. D. Crawford Transcranial Magnetic Stimulation over Posterior Parietal Cortex Disrupts Transsaccadic Memory of Multiple Objects J. Neurosci., July 2, 2008; 28(27): 6938 - 6949. [Abstract] [Full Text] [PDF]

				S. Van Pelt and W. P. Medendorp Updating Target Distance Across Eye Movements in Depth J Neurophysiol, May 1, 2008; 99(5): 2281 - 2290. [Abstract] [Full Text] [PDF]

				J. L. Gardner, E. P. Merriam, J. A. Movshon, and D. J. Heeger Maps of Visual Space in Human Occipital Cortex Are Retinotopic, Not Spatiotopic J. Neurosci., April 9, 2008; 28(15): 3988 - 3999. [Abstract] [Full Text] [PDF]

				S. Ryan, A. Pellijeff, C. Preston, and K. McKenzie Spatial Updating in a Three-Dimensional World J. Neurosci., July 11, 2007; 27(28): 7363 - 7364. [Full Text] [PDF]