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REPORT
1Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland; 2Institut National de la Santé et de la Recherche Médicale (INSERM), U731, Paris, France; 3Université Pierre et Marie Curie-Paris 6, Unité Mixte de Recherche S731, Paris, France; and 4INSERM, U 825, Toulouse F-31059 France, Hôpital Purpan, Fédération de Neurologie, Toulouse, France
Submitted 11 October 2006; accepted in final form 19 January 2007
Repetitive pairing of a peripheral stimulation with a magnetic transcortical stimulation (PAS) is widely used to induce plastic changes in the human motor cortex noninvasively. Based on the contrast between PAS-induced increase of corticospinal excitability and absence of PAS-induced increase of the spinal F wave size, it has been generally accepted that PAS-induced plasticity is cortical in origin. Here, instead of F waves, we used H reflex recruitment curves to assess spinal excitability, and we demonstrate that PAS induces parallel changes in cortical and spinal excitability.
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