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J Neurophysiol (February 11, 2009). doi:10.1152/jn.00009.2009
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Submitted on January 6, 2009
Revised on January 27, 2009
Accepted on February 2, 2009

Using Light to Reinstate Respiratory Plasticity

Benjamin Russell Arenkiel1* and Jaoa Peca1

1 Duke University Medical Center

* To whom correspondence should be addressed. E-mail: arenkiel{at}neuro.duke.edu.

Restoring normal function to damaged or diseased nervous tissue remains a major goal of both basic and clinical neuroscience research. Advances in genetic technologies now allow targeted control of neuronal activity in the mammalian nervous system, providing novel therapeutic avenues to repair or bypass faulty circuits. Here we review recent work published in the Journal of Neuroscience by Alilain et al., demonstrating the use of Channelrhodopsin-2 to restore breathing in rodent models of spinal cord injury.






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