JN Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
 QUICK SEARCH:   [advanced]


     


J Neurophysiol (April 28, 2004). doi:10.1152/jn.00088.2004
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
92/3/1944    most recent
00088.2004v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Huang, Y.
Right arrow Articles by Miller, J. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Huang, Y.
Right arrow Articles by Miller, J. P.
Submitted on January 29, 2004
Accepted on April 10, 2004

Phased Array Processing for Spike Discrimination

Yikun Huang* and John P. Miller

* To whom correspondence should be addressed. E-mail: yikun{at}cns.montana.edu.

We present a novel approach for the detection, discrimination and identification of superimposed neuronal action potentials from multi-neuronal, multi-channel extracellular nerve recordings with low signal-to-noise ratios. The approach employs phased array processing technique to identify the spikes from different neurons on the basis of their unique propagation velocities. We evaluated this new approach using simulated electrophysiological data, under conditions that are known to limit the effectiveness of existing spike discrimination techniques. This approach enabled discrimination of simulated spikes from multiple simultaneously-active neurons with a high degree of reliability and robustness within the expected range of experimental recording conditions, even in situations where there was a high degree of spike waveform superposition on the recording channels. Moreover, the technique enables the reliable detection and discrimination of spikes recorded with signal-to-noise ratios less than 1.







HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 2004 by the The American Physiological Society.