| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Engineering, University of Leicester, Leicester, United Kingdom
2 Biology, Caltech, Pasadena, California, United States
3 Caltech; Caltech, United States
4 Neurosurgery, UCLA, Los Angeles, California, United States
* To whom correspondence should be addressed. E-mail: rodri{at}vis.caltech.edu.
We investigated the representation of visual inputs by multiple simultaneously recorded single neurons in the human medial temporal lobe, using their firing rates to infer which images were shown to subjects. The selectivity of these neurons was quantified with a novel measure. About 4 spikes per neuron, triggered between 300-600 ms following image onset in a handful of units (7.8 on average), predicted the identity of images far above chance. Decoding performance increased linearly with the number of units considered, peaked between 400 and 500 ms, did not improve when considering correlations among simultaneously recorded units, and generalized to very different images. The feasibility of decoding sensory information from human extracellular recordings has implications for the development of brain-machine-interfaces.
This article has been cited by other articles:
|
|
 |
|
  F. Mormann, S. Kornblith, R. Q. Quiroga, A. Kraskov, M. Cerf, I. Fried, and C. Koch Latency and Selectivity of Single Neurons Indicate Hierarchical Processing in the Human Medial Temporal Lobe J. Neurosci., September 3, 2008; 28(36): 8865 - 8872. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Q. Quiroga, R. Mukamel, E. A. Isham, R. Malach, and I. Fried Human single-neuron responses at the threshold of conscious recognition PNAS, March 4, 2008; 105(9): 3599 - 3604. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
