JN AJP: Advances in Physiology Education
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

J Neurophysiol (May 26, 2004). doi:10.1152/jn.00154.2004
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
92/4/1990    most recent
00154.2004v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Raos, V.
Right arrow Articles by Fogassi, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Raos, V.
Right arrow Articles by Fogassi, L.
Submitted on February 17, 2004
Accepted on May 20, 2004

Functional properties of grasping-related neurons in the dorsal premotor area F2 of the macaque monkey

Vassilis Raos1*, Maria-Alessandra Umilta1, Vittorio Gallese1, and Leonardo Fogassi1

1 Dipartimento di Neuroscienze, Sezione di Fisiologia, Universita di Parma, Parma, Parma, Italy

* To whom correspondence should be addressed. E-mail: vraos{at}med.uoc.gr.

We investigated the properties of neurons located in the distal forelimb field of dorsal premotor area F2 of macaque monkey employing a behavioral paradigm for studying the neuronal discharge during observation (object fixation condition) and grasping of different three-dimensional objects with and without visual guidance of the movement (movement in light and movement in dark conditions, respectively). The main result is that almost all studied neurons were selective for both the type of prehension and the wrist orientation required for grasping an object. Three categories of neurons were found: purely motor, visually-modulated and visuomotor neurons. The discharge of purely motor neurons was not affected by either object presentation or by the visual feedback of the hand approaching to and interacting with the object. Visually-modulated neurons presented a different discharge in the two movement conditions, this determining a decrease in selectivity for the grip and wrist orientation in the movement in dark condition. Visuomotor neurons typically discharged during the object fixation task even in the absence of any grasping movement. Nine of them also displayed different discharge rate between the two movement conditions. Congruence was observed between the neuron response during the most effective type of prehension and the neuron response during observation of the object requiring that particular prehension. These results indicate an important role of F2 in the control of goal-related hand movements.




This article has been cited by other articles:


Home page
 J. Neurosci.Home page
E. Stark, A. Globerson, I. Asher, and M. Abeles
Correlations between Groups of Premotor Neurons Carry Information about Prehension
J. Neurosci., October 15, 2008; 28(42): 10618 - 10630.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
E. Borra, A. Belmalih, R. Calzavara, M. Gerbella, A. Murata, S. Rozzi, and G. Luppino
Cortical Connections of the Macaque Anterior Intraparietal (AIP) Area
Cereb Cortex, May 1, 2008; 18(5): 1094 - 1111.
[Abstract] [Full Text] [PDF]

Home page
 NeuroscientistHome page
U. Castiello and C. Begliomini
The Cortical Control of Visually Guided Grasping
Neuroscientist, April 1, 2008; 14(2): 157 - 170.
[Abstract] [PDF]

Home page
 J. Neurophysiol.Home page
E. P. Gardner, K. S. Babu, S. Ghosh, A. Sherwood, and J. Chen
Neurophysiology of Prehension. III. Representation of Object Features in Posterior Parietal Cortex of the Macaque Monkey
J Neurophysiol, December 1, 2007; 98(6): 3708 - 3730.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Umilta, T. Brochier, R. L. Spinks, and R. N. Lemon
Simultaneous Recording of Macaque Premotor and Primary Motor Cortex Neuronal Populations Reveals Different Functional Contributions to Visuomotor Grasp
J Neurophysiol, July 1, 2007; 98(1): 488 - 501.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. Stark, I. Asher, and M. Abeles
Encoding of Reach and Grasp by Single Neurons in Premotor Cortex Is Independent of Recording Site
J Neurophysiol, May 1, 2007; 97(5): 3351 - 3364.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. P. Gardner, K. S. Babu, S. D. Reitzen, S. Ghosh, A. S. Brown, J. Chen, A. L. Hall, M. D. Herzlinger, J. B. Kohlenstein, and J. Y. Ro
Neurophysiology of Prehension. I. Posterior Parietal Cortex and Object-Oriented Hand Behaviors
J Neurophysiol, January 1, 2007; 97(1): 387 - 406.
[Abstract] [Full Text] [PDF]

Home page
 Cereb CortexHome page
S. Rozzi, R. Calzavara, A. Belmalih, E. Borra, G. G. Gregoriou, M. Matelli, and G. Luppino
Cortical Connections of the Inferior Parietal Cortical Convexity of the Macaque Monkey
Cereb Cortex, October 1, 2006; 16(10): 1389 - 1417.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
V. Raos, M.-A. Umilta, A. Murata, L. Fogassi, and V. Gallese
Functional Properties of Grasping-Related Neurons in the Ventral Premotor Area F5 of the Macaque Monkey
J Neurophysiol, February 1, 2006; 95(2): 709 - 729.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 2004 by the The American Physiological Society.