| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Department of Anatomy and Neurobiology, University of California Irvine, Irvine, CA, USA
2 Department of Cognitive Science, University of California Irvine, Irvine, CA, USA
* To whom correspondence should be addressed. E-mail: lmkitzes{at}uci.edu.
The binaural interactions of neurons were studied in the primary auditory cortex (AI) of barbiturate-anesthetized cats within a matrix of binaural tonal stimuli varying in both interaural level differences (ILD) and average binaural level (ABL). The purpose of this study was to determine: (1) the distribution of preferred binaural combinations (PBCs) of a large population of neurons and its relationships with binaural interactions and binaural monotonicity; (2) whether monaural responses are predictive of binaural responses; and (3) whether there was a restricted set of representative binaural stimulus configurations that could effectively classify the binaural interactions. Binaural interactions were often diverse in the matrix and dependent on ABL and ILD. Compared with previous studies, a higher proportion of mixed binaural interaction type and a lower proportion of EO/I type were found. No monaural neurons were found. Binaural responses often differed from monaural responses in the number of spikes and/or the form of the response functions. The PBCs of the majority of EO and PB neurons were in the contralateral field and midline, respectively. However, the PBCs of EE units were evenly distributed across the contralateral and ipsilateral fields. The majority of the nonmonotonic neurons responded most strongly to lower ABLs whereas the majority of monotonic neurons responded most strongly to higher ABLs. This study demonstrated that in primary auditory cortex a restricted set of binaural stimulus configurations is not sufficient to reveal the binaural responses properties. Also monaural responses are not predictive of binaural responses.
This article has been cited by other articles:
|
|
 |
|
  R. A. A. Campbell, J. W. H. Schnupp, A. Shial, and A. J. King Binaural-Level Functions in Ferret Auditory Cortex: Evidence for a Continuous Distribution of Response Properties J Neurophysiol, June 1, 2006; 95(6): 3742 - 3755. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. T. Nakamoto, J. Zhang, and L. M. Kitzes Temporal Nonlinearity During Recovery From Sequential Inhibition by Neurons in the Cat Primary Auditory Cortex J Neurophysiol, March 1, 2006; 95(3): 1897 - 1907. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Zhang, K. T. Nakamoto, and L. M. Kitzes Modulation of Level Response Areas and Stimulus Selectivity of Neurons in Cat Primary Auditory Cortex J Neurophysiol, October 1, 2005; 94(4): 2263 - 2274. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Ojima, M. Takayanagi, D. Potapov, and R. Homma Isofrequency Band-like Zones of Activation Revealed by Optical Imaging of Intrinsic Signals in the Cat Primary Auditory Cortex Cereb Cortex, October 1, 2005; 15(10): 1497 - 1509. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. D. Mrsic-Flogel, A. J. King, and J. W. H. Schnupp Encoding of Virtual Acoustic Space Stimuli by Neurons in Ferret Primary Auditory Cortex J Neurophysiol, June 1, 2005; 93(6): 3489 - 3503. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. T. Nakamoto, J. Zhang, and L. M. Kitzes Response Patterns Along an Isofrequency Contour in Cat Primary Auditory Cortex (AI) to Stimuli Varying in Average and Interaural Levels J Neurophysiol, January 1, 2004; 91(1): 118 - 135. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
