| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Graduate Program in Neurobiology and Behavior, University of Washington, Seattle, Washington, United States; Washington National Regional Primate Research Center, University of Washington, Seattle, Washington, United States
2 Department of Physiology & Biophysics, University of Washington, Seattle, Washington, United States; Washington National Regional Primate Research Center, University of Washington, Seattle, Washington, United States; Graduate Program in Neurobiology and Behavior, University of Washington, Seattle, Washington, United States
* To whom correspondence should be addressed. E-mail: fuchs{at}washington.edu.
The role of the primate frontal eye field (FEF) has been inferred primarily from experiments investigating saccadic eye movements with the head restrained. Three recent reports investigating head-unrestrained gaze shifts disagree on whether head movements are evoked with FEF stimulation, and therefore whether the FEF participates in gaze movement commands. We therefore examined the eye, head, and overall gaze movement evoked by low-intensity microstimulation of the low-threshold region of the FEF in two head-unrestrained monkeys. Microstimulation applied at 200 or 350 Hz for 200 ms evoked large gaze shifts with substantial head movement components from most sites in the dorsomedial FEF, but evoked small, predominantly eye-only gaze shifts from ventrolateral sites. The size and direction of gaze and eye movements were strongly affected by the eye position prior to stimulation. Head movements exhibited little position-dependence, but at some sites and initial eye positions, head-only movements were evoked. Stimulus-evoked gaze shifts and their eye and head components resembled those elicited naturally by visual targets. With stimulus train durations greater than 200 ms, the evoked gaze shifts were more likely to be accomplished with a substantial head movement, which often continued for the entire stimulus duration. The amplitude, duration and peak velocity of the evoked head movement were more strongly correlated with stimulus duration than were those of the gaze or eye movements. We conclude that the dorsomedial FEF generates a gaze command signal that can produce eye, head, or combined eye-head movement depending on the initial orbital position of the eye.
This article has been cited by other articles:
|
|
 |
|
  S. Ono and M. J. Mustari Smooth Pursuit-Related Information Processing in Frontal Eye Field Neurons that Project to the NRTP Cereb Cortex, May 1, 2009; 19(5): 1186 - 1197. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Fukushima, S. Kasahara, T. Akao, S. Kurkin, J. Fukushima, and B. W. Peterson Eye-Pursuit and Reafferent Head Movement Signals Carried by Pursuit Neurons in the Caudal Part of the Frontal Eye Fields during Head-Free Pursuit Cereb Cortex, February 1, 2009; 19(2): 263 - 275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Z. Khan, G. Blohm, R. M. McPeek, and P. Lefevre Differential Influence of Attention on Gaze and Head Movements J Neurophysiol, January 1, 2009; 101(1): 198 - 206. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. K. Murphey and J. H. R. Maunsell Electrical microstimulation thresholds for behavioral detection and saccades in monkey frontal eye fields PNAS, May 20, 2008; 105(20): 7315 - 7320. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. G. Walton, B. Bechara, and N. J. Gandhi Effect of Reversible Inactivation of Superior Colliculus on Head Movements J Neurophysiol, May 1, 2008; 99(5): 2479 - 2495. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. G. Walton, B. Bechara, and N. J. Gandhi Role of the Primate Superior Colliculus in the Control of Head Movements J Neurophysiol, October 1, 2007; 98(4): 2022 - 2037. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. K. Elsley, B. Nagy, S. L. Cushing, and B. D. Corneil Widespread Presaccadic Recruitment of Neck Muscles by Stimulation of the Primate Frontal Eye Fields J Neurophysiol, September 1, 2007; 98(3): 1333 - 1354. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. J. Gandhi and D. L. Sparks Dissociation of Eye and Head Components of Gaze Shifts by Stimulation of the Omnipause Neuron Region J Neurophysiol, July 1, 2007; 98(1): 360 - 373. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
