| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Neurosurgery, Univ. Iowa, Iowa City, IA, USA; Physiology, Univ. Wisconsin, Madison, WI, USA; Waisman Center, Univ. Wisconsin, Madison, WI, USA
2 Neurosurgery, Univ. Iowa, Iowa City, IA, USA
3 Waisman Center, Univ. Wisconsin, Madison, WI, USA; Physiology, Univ. Wisconsin, Madison, WI, USA
* To whom correspondence should be addressed. E-mail: brugge{at}waisman.wisc.edu.
Functional connections between auditory fields on Heschl's gyrus (HG) and the acoustically responsive posterior lateral superior temporal gyrus (field PLST) were studied using electrical stimulation and recording methods in patients undergoing diagnosis and treatment of intractable epilepsy. Averaged auditory (click train) evoked potentials were recorded from multicontact subdural recording arrays chronically implanted over the lateral surface of the superior temporal gyrus (STG) and from modified depth electrodes inserted into HG. Biphasic electrical pulses (bipolar, constant current, 0.2 ms) were delivered to HG sites while recording from the electrode array over acoustically responsive STG cortex. Stimulation of sites along the medial-lateral extent of HG resulted in complex waveforms distributed over posterolateral STG. These areas overlapped each other and field PLST. For any given HG stimulus site, the morphology of the electrically evoked waveform varied across the STG map. A characteristic waveform was recorded at the site of maximal amplitude of response to stimulation of mesial HG (presumed AI). Latency measurements suggest that the earliest evoked wave resulted from activation of connections within cortex. Waveforms changed with changes in rate of electrical HG stimulation or with shifts in the HG stimulus site. Data suggest widespread convergence and divergence of input from HG to posterior STG. Evidence is presented for a reciprocal functional projection, from posterolateral STG to HG. Results indicate that in the human there exists a processing stream from primary auditory cortex on mesial HG to an associational auditory field (PLST) on the lateral surface of the superior temporal gyrus.
This article has been cited by other articles:
|
|
 |
|
  J. Upadhyay, A. Silver, T. A. Knaus, K. A. Lindgren, M. Ducros, D.-S. Kim, and H. Tager-Flusberg Effective and Structural Connectivity in the Human Auditory Cortex J. Neurosci., March 26, 2008; 28(13): 3341 - 3349. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D Patterson and I. S Johnsrude Functional imaging of the auditory processing applied to speech sounds Phil Trans R Soc B, March 12, 2008; 363(1493): 1023 - 1035. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Steinschneider, Y. I. Fishman, and J. C. Arezzo Spectrotemporal Analysis of Evoked and Induced Electroencephalographic Responses in Primary Auditory Cortex (A1) of the Awake Monkey Cereb Cortex, March 1, 2008; 18(3): 610 - 625. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Gueguin, R. Le Bouquin-Jeannes, G. Faucon, P. Chauvel, and C. Liegeois-Chauvel Evidence of Functional Connectivity between Auditory Cortical Areas Revealed by Amplitude Modulation Sound Processing Cereb Cortex, February 1, 2007; 17(2): 304 - 313. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. De Santis, S. Clarke, and M. M. Murray Automatic and Intrinsic Auditory "What" and "Where" Processing in Humans Revealed by Electrical Neuroimaging Cereb Cortex, January 1, 2007; 17(1): 9 - 17. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. M. Murray, C. Camen, S. L. Gonzalez Andino, P. Bovet, and S. Clarke Rapid Brain Discrimination of Sounds of Objects J. Neurosci., January 25, 2006; 26(4): 1293 - 1302. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Inui, H. Okamoto, K. Miki, A. Gunji, and R. Kakigi Serial and Parallel Processing in the Human Auditory Cortex: A Magnetoencephalographic Study Cereb Cortex, January 1, 2006; 16(1): 18 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Duffau, P. Gatignol, E. Mandonnet, P. Peruzzi, N. Tzourio-Mazoyer, and L. Capelle New insights into the anatomo-functional connectivity of the semantic system: a study using cortico-subcortical electrostimulations Brain, April 1, 2005; 128(4): 797 - 810. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Matsumoto, D. R. Nair, E. LaPresto, I. Najm, W. Bingaman, H. Shibasaki, and H. O. Luders Functional connectivity in the human language system: a cortico-cortical evoked potential study Brain, October 1, 2004; 127(10): 2316 - 2330. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. W. Greenlee, H. Oya, H. Kawasaki, I. O. Volkov, O. P. Kaufman, C. Kovach, M. A. Howard, and J. F. Brugge A Functional Connection Between Inferior Frontal Gyrus and Orofacial Motor Cortex in Human J Neurophysiol, August 1, 2004; 92(2): 1153 - 1164. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
