JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

J Neurophysiol (January 14, 2004). doi:10.1152/jn.00970.2003
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
91/5/2117    most recent
00970.2003v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Massaux, A.
Right arrow Articles by Edeline, J.-M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Massaux, A.
Right arrow Articles by Edeline, J.-M.
Submitted on October 7, 2003
Accepted on January 12, 2004

Auditory thalamus bursts in anesthetized and non-anesthetized states: Contribution to functional properties

Aurelie Massaux, Gerard Dutrieux, Nathalie Cotillon-Williams, Yves Manunta, and Jean-Marc Edeline*

* To whom correspondence should be addressed. E-mail: jean-marc.edeline{at}ibaic.u-psud.fr.

Over the last ten years, high frequency bursts of action potentials have been the subject of intense researches to understand their potential role in information encoding. Based on recordings from auditory thalamus neurons (n=302) collected during anesthesia (Pentobarbital, Urethane or Ketamine/Xylazine), waking (W) and slow-wave sleep (SWS), we investigated how bursts participate to frequency tuning, intensity-function, response latency (and latency variability) and stimulus detectability. Although present in all experimental conditions, bursts never dominated the cells mode of discharge: the highest proportion was found during Ketamine/Xylazine anesthesia (22%), the lowest during waking (4.5%). In all experimental conditions, bursts preferentially occurred at or around the cells best frequency (BF), thus increasing the frequency selectivity. This effect was observed at both the intensities producing the highest and the lowest evoked responses. Testing the intensity-functions indicated that, for most of the cells, there was no systematic relationship between bursts proportion and responses strength. Under several conditions (W, SWS and Urethane), when cells exhibited bursts above 20%, the variability of their response latency was reduced in burst mode compared with single spike mode. During W, this effect was accompagnied by a reduction of the response latency. Finally, a ROC analysis indicated no particular relation between bursts and stimulus detectability. Compared with single spike mode which is present for broader frequency ranges, the prominence of bursts at the BF should contribute to filter information reaching the targets of MG cells at both cortical and subcortical levels.




This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
N. Cotillon-Williams, C. Huetz, E. Hennevin, and J.-M. Edeline
Tonotopic Control of Auditory Thalamus Frequency Tuning by Reticular Thalamic Neurons
J Neurophysiol, March 1, 2008; 99(3): 1137 - 1151.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
M. Xu, C. H. Liu, Y. Xiong, and J. He
Corticofugal modulation of the auditory thalamic reticular nucleus of the guinea pig
J. Physiol., November 15, 2007; 585(1): 15 - 28.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. N. Wallace, L. A. Anderson, and A. R. Palmer
Phase-Locked Responses to Pure Tones in the Auditory Thalamus
J Neurophysiol, October 1, 2007; 98(4): 1941 - 1952.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
H. Xu, V. C. Kotak, and D. H. Sanes
Conductive Hearing Loss Disrupts Synaptic and Spike Adaptation in Developing Auditory Cortex
J. Neurosci., August 29, 2007; 27(35): 9417 - 9426.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
S.-H. Lee, G. Govindaiah, and C. L. Cox
Heterogeneity of firing properties among rat thalamic reticular nucleus neurons
J. Physiol., July 1, 2007; 582(1): 195 - 208.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A.-M. M. Oswald, B. Doiron, and L. Maler
Interval Coding. I. Burst Interspike Intervals as Indicators of Stimulus Intensity
J Neurophysiol, April 1, 2007; 97(4): 2731 - 2743.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
O. Ruiz, D. Royal, G. Sary, X. Chen, J. D. Schall, and V. A. Casagrande
Low-Threshold Ca2+-Associated Bursts Are Rare Events in the LGN of the Awake Behaving Monkey
J Neurophysiol, June 1, 2006; 95(6): 3401 - 3413.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. Engelmann, J. Bacelo, E. van den Burg, and K. Grant
Sensory and Motor Effects of Etomidate Anesthesia
J Neurophysiol, February 1, 2006; 95(2): 1231 - 1243.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
H. J. Rose and R. Metherate
Auditory Thalamocortical Transmission Is Reliable and Temporally Precise
J Neurophysiol, September 1, 2005; 94(3): 2019 - 2030.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
E. J. Ramcharan, J. W. Gnadt, and S. M. Sherman
Higher-order thalamic relays burst more than first-order relays
PNAS, August 23, 2005; 102(34): 12236 - 12241.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. S. Grubb and I. D. Thompson
Visual Response Properties of Burst and Tonic Firing in the Mouse Dorsal Lateral Geniculate Nucleus
J Neurophysiol, June 1, 2005; 93(6): 3224 - 3247.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. S. Denning and P. Reinagel
Visual Control of Burst Priming in the Anesthetized Lateral Geniculate Nucleus
J. Neurosci., April 6, 2005; 25(14): 3531 - 3538.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 2004 by the The American Physiological Society.