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1 Medecine physique et readaptation, INSERM U731/UPMC, Paris 75651, Paris, France; , 28 avenue de touraine, Sceaux, Hauts de seine, 92330, France
2 HMCS, NIH/NINDS, Bethesda, Maryland, United States
3 federation de neurologie, INSERM U825, Toulouse, France
4 NINDS, National Institutes of Health, Bethesda, Maryland, United States
* To whom correspondence should be addressed. E-mail: meunier.sabine{at}free.fr.
Repetitive pairing of a peripheral stimulation with a magnetic transcortical stimulation (PAS) is widely used to induce plastic changes in the human motor cortex non-invasively. Based on the contrast between PAS-induced increase of corticospinal excitability and absence of PAS-induced increase of the spinal F wave size it has been generally accepted that PAS-induced plasticity is cortical in origin. Here, instead of F waves, we used H reflex recruitment curves to assess spinal excitability, and we demonstrate that PAS induces parallel changes in cortical and spinal excitability.
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