Submitted on February 13, 2008
Revised on April 25, 2008
Accepted on May 18, 2008
Time and Frequency Characteristics of Purkinje Cell Complex Spikes in the Awake Monkey Performing a Non-Periodic Task
Shahin Hakimian, Scott A Norris, Bradley Greger1, jeff g keating2, Charles H Anderson, and William Thomas Thach3*
1 University of Utah
2 University of Pennsylvania
3 Washington University
* To whom correspondence should be addressed. E-mail: thachw{at}pcg.wustl.edu.
A number of studies have been interpreted to support the view that the inferior olive climbing fibers send periodic signals to the cerebellum to time and pace behavior. In a direct test of this hypothesis in macaques performing non-periodic tasks, we analyzed continuous recordings of Complex Spikes from the lateral cerebellar hemisphere. We found no periodicity outside of a 100 ms relative refractory period.
