JN Watch the video to learn how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 91: 2164-2171, 2004. First published December 24, 2003; doi:10.1152/jn.01147.2003
0022-3077/04 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
91/5/2164    most recent
01147.2003v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (13)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Haftel, V. K.
Right arrow Articles by Cope, T. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Haftel, V. K.
Right arrow Articles by Cope, T. C.

Movement Reduces the Dynamic Response of Muscle Spindle Afferents and Motoneuron Synaptic Potentials in Rat

Valerie K. Haftel1, Edyta K. Bichler1,2, T. Richard Nichols1, Martin J. Pinter1 and Timothy C. Cope1

1Department of Physiology, Emory University, Atlanta, Georgia 30322; and 2Department of Neurobiology, University School of Physical Education, Poznan 60352, Poland

Submitted 1 December 2003; accepted in final form 23 December 2003

Among the mechanisms that may result in modulation of the stretch reflex by the recent history of muscle contraction is the history dependence observed under some conditions in the response properties of muscle spindles. The present study was designed to test one report that in successive trials of muscle stretch-release, spindle afferent firing during stretch, i.e., the dynamic response shows no history dependence beyond the initial burst of firing at stretch onset. Firing responses of spindle afferents were recorded during sets of three consecutive trials of triangular stretch-release applied to triceps surae muscles in barbiturate-anesthetized rats. All 69 spindle afferents fired more action potentials (spikes) during the dynamic response of the first trial, excluding the initial burst, than in the following two trials. The reduced dynamic response (RDR) was nearly complete after trial 1 and amounted to an average of ~12 fewer spikes (16 pps slower firing rate) in trial 3 than in trial 1. RDR was sensitive to the interval between stretch sets but independent of stretch velocity (4–32 mm/s). RDR was reflected in the synaptic potentials recorded intracellularly from 16 triceps surae {alpha}-motoneurons: depolarization during muscle stretch was appreciably reduced after trial 1. These findings demonstrate history dependence of spindle afferent responses that extends throughout the dynamic response in successive muscle stretches and that is synaptically transmitted to motoneurons with the probable effect, unless otherwise compensated, of modulating the stretch reflex.

Address for reprint requests and other correspondence: V. K. Haftel, Dept. of Biology, Morehouse College, Atlanta, Georgia 30314 (E-mail: vhaftel{at}morehouse.edu).




This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
T. D. J. Welch and L. H. Ting
A Feedback Model Explains the Differential Scaling of Human Postural Responses to Perturbation Acceleration and Velocity
J Neurophysiol, June 1, 2009; 101(6): 3294 - 3309.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. T. Ross and T. R. Nichols
Heterogenic Feedback Between Hindlimb Extensors in the Spontaneously Locomoting Premammillary Cat
J Neurophysiol, January 1, 2009; 101(1): 184 - 197.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. K. Bichler, S. T. Nakanishi, Q.-B. Wang, M. J. Pinter, M. M. Rich, and T. C. Cope
Enhanced Transmission at a Spinal Synapse Triggered In Vivo by an Injury Signal Independent of Altered Synaptic Activity
J. Neurosci., November 21, 2007; 27(47): 12851 - 12859.
[Abstract] [Full Text] [PDF]

Home page
 Integr. Comp. Biol.Home page
K. Nishikawa, A. A. Biewener, P. Aerts, A. N. Ahn, H. J. Chiel, M. A. Daley, T. L. Daniel, R. J. Full, M. E. Hale, T. L. Hedrick, et al.
Neuromechanics: an integrative approach for understanding motor control
Integr. Comp. Biol., July 1, 2007; 47(1): 16 - 54.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. P. Mileusnic, I. E. Brown, N. Lan, and G. E. Loeb
Mathematical Models of Proprioceptors. I. Control and Transduction in the Muscle Spindle
J Neurophysiol, October 1, 2006; 96(4): 1772 - 1788.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
T. G. Hornby, J. H. Kahn, M. Wu, and B. D. Schmit
Temporal facilitation of spastic stretch reflexes following human spinal cord injury
J. Physiol., March 15, 2006; 571(3): 593 - 604.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
R. Durbaba, A. Taylor, P. H. Ellaway, and S. Rawlinson
Classification of longissimus lumborum muscle spindle afferents in the anaesthetized cat
J. Physiol., March 1, 2006; 571(2): 489 - 498.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
V. K. Haftel, E. K. Bichler, Q.-B. Wang, J. F. Prather, M. J. Pinter, and T. C. Cope
Central Suppression of Regenerated Proprioceptive Afferents
J. Neurosci., May 11, 2005; 25(19): 4733 - 4742.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2004 by the The American Physiological Society.