HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) All Versions of this Article: 92/6/3408    most recent 01156.2003v1 Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (16) Citing Articles via Google Scholar Google Scholar Articles by Cullen, K. E. Articles by Sylvestre, P. A. Search for Related Content PubMed PubMed Citation Articles by Cullen, K. E. Articles by Sylvestre, P. A.

Time Course of Vestibuloocular Reflex Suppression During Gaze Shifts

Aerospace Medical Research Unit, McGill University, Montreal, Quebec H3G 1Y6, Canada

Submitted 2 December 2003; accepted in final form 18 June 2004

Although numerous investigations have probed the status of the vestibuloocular (VOR) during gaze shifts, its exact status remains strangely elusive. The goal of the present study was to precisely evaluate the dynamics of VOR suppression immediately before, throughout, and just after gaze shifts. A torque motor was used to apply rapid (100°/s), short-duration (20–30 ms) horizontal head perturbations in three Rhesus monkeys. The status of the VOR elicited by this transient head perturbation was first compared during 15, 40, and 60° gaze shifts. The level of VOR suppression just after gaze-shift onset (40 ms) increased with gaze-shift amplitude in two monkeys, approaching values of 80 and 35%. In contrast, in the third monkey, the VOR was not significantly attenuated for all gaze-shift amplitudes. The time course of VOR attenuation was then studied in greater detail for all three monkeys by imposing the same short-duration head perturbations 40, 100, and 150 ms after the onset of 60° gaze shifts. Overall we found a consistent trend, in which VOR suppression was maximal early in the gaze shift and progressively recovered to reach normal values near gaze-shift end. However, the high variability across subjects prevented establishing a unifying description of the absolute level and time course of VOR suppression during gaze shifts. We propose that differences in behavioral strategies may account, at least in part, for these differences between subjects.

This article has been cited by other articles:

				D. A. Suzuki, K. F. Betelak, and R. D. Yee Gaze Pursuit Responses in Nucleus Reticularis Tegmenti Pontis of Head-Unrestrained Macaques J Neurophysiol, January 1, 2009; 101(1): 460 - 473. [Abstract] [Full Text] [PDF]

				E. G. Freedman Coupling Between Horizontal and Vertical Components of Saccadic Eye Movements During Constant Amplitude and Direction Gaze Shifts in the Rhesus Monkey J Neurophysiol, December 1, 2008; 100(6): 3375 - 3393. [Abstract] [Full Text] [PDF]

				A. Guillaume and D. Pelisson Kinematics and eye-head coordination of gaze shifts evoked from different sites in the superior colliculus of the cat J. Physiol., December 15, 2006; 577(3): 779 - 794. [Abstract] [Full Text] [PDF]

				L. L. Chen Head Movements Evoked by Electrical Stimulation in the Frontal Eye Field of the Monkey: Evidence for Independent Eye and Head Control J Neurophysiol, June 1, 2006; 95(6): 3528 - 3542. [Abstract] [Full Text] [PDF]

				P. A. Sylvestre and K. E. Cullen Premotor correlates of integrated feedback control for eye-head gaze shifts. J. Neurosci., May 3, 2006; 26(18): 4922 - 4929. [Abstract] [Full Text] [PDF]

				A. F. Fuchs, L. Ling, and J. O. Phillips Behavior of the Position Vestibular Pause (PVP) Interneurons of the Vestibuloocular Reflex During Head-Free Gaze Shifts in the Monkey J Neurophysiol, December 1, 2005; 94(6): 4481 - 4490. [Abstract] [Full Text] [PDF]